Basic Information

Terpenoid ID TKC040829
Chirality TKC105378
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 8

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC040829 P08684 Cytochrome P450 3A4 CYP3A4 12589 nM Potency
TKC040829 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 102 % Inhibition
TKC040829 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 103 % Inhibition
TKC040829 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 316 nM Potency
TKC040829 O42275 Acetylcholinesterase ache 11 % Inhibition
TKC040829 P22771 Glycine receptor subunit alpha-2 Glra2 2400 nM IC50
TKC040829 P81908 Cholinesterase BCHE -4 % Inhibition
TKC040829 Q01196 Runt-related transcription factor 1 RUNX1 12589 nM Potency
TKC040829 O09028 Gamma-aminobutyric acid receptor subunit pi Gabrp 90 % Displacement

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]