TKC118419
|
O75116 |
Rho-associated protein kinase 2 |
None |
99 |
% |
Activity |
TKC007127
|
P00533 |
Epidermal growth factor receptor |
None |
19 |
% |
Inhibition |
TKC025462
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025466
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025475
|
P00533 |
Epidermal growth factor receptor |
None |
197 |
ug.mL-1 |
IC50 |
TKC071640
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC076041
|
P00533 |
Epidermal growth factor receptor |
None |
75 |
% |
Inhibition |
TKC077689
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC106319
|
P00533 |
Epidermal growth factor receptor |
None |
56 |
nM |
IC50 |
TKC108557
|
P00533 |
Epidermal growth factor receptor |
None |
0.82 |
nM |
Kd |
TKC151761
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC200866
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC005744
|
P00742 |
Coagulation factor X |
None |
27900 |
nM |
IC50 |
TKC012492
|
P00742 |
Coagulation factor X |
None |
13385 |
nM |
Ki |
TKC013400
|
P00742 |
Coagulation factor X |
None |
2500 |
nM |
IC50 |
TKC013430
|
P00742 |
Coagulation factor X |
None |
11418 |
nM |
IC50 |
TKC055903
|
P00742 |
Coagulation factor X |
None |
>20000 |
nM |
IC50 |
TKC107140
|
P00742 |
Coagulation factor X |
None |
7991 |
nM |
Ki |
TKC124270
|
P00742 |
Coagulation factor X |
None |
27558 |
nM |
Ki |
TKC128698
|
P00742 |
Coagulation factor X |
None |
7200 |
nM |
IC50 |
TKC128699
|
P00742 |
Coagulation factor X |
None |
7165 |
nM |
IC50 |
TKC205733
|
P00742 |
Coagulation factor X |
None |
1023 |
nM |
IC50 |
TKC051021
|
P01375 |
Tumor necrosis factor |
None |
9 |
nM |
Kd |
TKC051029
|
P01375 |
Tumor necrosis factor |
None |
9 |
nM |
Kd |
TKC055869
|
P01375 |
Tumor necrosis factor |
None |
10880 |
nM |
IC50 |
TKC063751
|
P01375 |
Tumor necrosis factor |
None |
19 |
nM |
Kd |
TKC064986
|
P01375 |
Tumor necrosis factor |
None |
3 |
nM |
Kd |
TKC075769
|
P01375 |
Tumor necrosis factor |
None |
376 |
nM |
Potency |
TKC101833
|
P01375 |
Tumor necrosis factor |
None |
8 |
nM |
Kd |
TKC145547
|
P01375 |
Tumor necrosis factor |
None |
2 |
nM |
Kd |
TKC148618
|
P01375 |
Tumor necrosis factor |
None |
17 |
nM |
Kd |
TKC151763
|
P01375 |
Tumor necrosis factor |
None |
8 |
nM |
Kd |
TKC151876
|
P01375 |
Tumor necrosis factor |
None |
6 |
% |
Inhibition |
TKC206051
|
P07858 |
Cathepsin B |
None |
103500 |
nM |
IC50 |
TKC024886
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
11800 |
nM |
IC50 |
TKC025690
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
3310 |
nM |
IC50 |
TKC115259
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
3160 |
nM |
IC50 |
TKC115261
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
2420 |
nM |
IC50 |
TKC115272
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
2300 |
nM |
IC50 |
TKC152148
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
2770 |
nM |
IC50 |
TKC152157
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
2460 |
nM |
IC50 |
TKC174547
|
P08069 |
Insulin-like growth factor 1 receptor |
None |
>100000 |
nM |
IC50 |
TKC151523
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
>100000 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
4500 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
1500 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
642 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
1258.92 |
nM |
Ki |
TKC206544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
>10000 |
nM |
Ki |
TKC206549
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
30 |
pM well-1 |
cAMP |
TKC020117
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
-67 |
% |
Inhibition |
TKC024485
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>50000 |
nM |
IC50 |
TKC024587
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
600 |
nM |
IC50 |
TKC024956
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
18000 |
nM |
IC50 |
TKC024992
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
450 |
nM |
IC50 |
TKC024993
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
14000 |
nM |
IC50 |
TKC025965
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>150000 |
nM |
IC50 |
TKC026303
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
4600 |
nM |
IC50 |
TKC026309
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
680 |
nM |
IC50 |
TKC027255
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>67 |
% |
Activity |
TKC034201
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>200000 |
nM |
IC50 |
TKC040026
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
72 |
% |
Inhibition |
TKC051154
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
2700 |
nM |
IC50 |
TKC056482
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>64 |
% |
Activity |
TKC058811
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
42000 |
nM |
IC50 |
TKC058812
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>93 |
% |
Activity |
TKC064374
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
42000 |
nM |
IC50 |
TKC064407
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>72 |
% |
Activity |
TKC065375
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>70 |
% |
Activity |
TKC071640
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>60 |
% |
Activity |
TKC076350
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
100 |
% |
Activity |
TKC077689
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
100 |
% |
Activity |
TKC077703
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>86 |
% |
Activity |
TKC078194
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
31800 |
nM |
IC50 |
TKC082039
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
48 |
% |
Inhibition |
TKC088678
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
24800 |
nM |
IC50 |
TKC089448
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
35 |
% |
Inhibition |
TKC094647
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
97 |
% |
Activity |
TKC107943
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
2000 |
nM |
IC50 |
TKC123028
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
30400 |
nM |
IC50 |
TKC124303
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
750 |
nM |
IC50 |
TKC133309
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>200000 |
nM |
IC50 |
TKC133656
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
25100 |
nM |
IC50 |
TKC134278
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>200000 |
nM |
IC50 |
TKC139322
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>67 |
% |
Activity |
TKC139366
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
3000 |
nM |
IC50 |
TKC141401
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
42000 |
nM |
IC50 |
TKC141499
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
25700 |
nM |
IC50 |
TKC141805
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>53 |
% |
Activity |
TKC142849
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>70 |
% |
Activity |
TKC142897
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
30600 |
nM |
IC50 |
TKC142922
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>61 |
% |
Activity |
TKC143539
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
100 |
% |
Activity |
TKC145848
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
42000 |
nM |
IC50 |
TKC145932
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>56 |
% |
Activity |
TKC145968
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
100 |
% |
Activity |
TKC146774
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>63 |
% |
Activity |
TKC149759
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>73 |
% |
Activity |
TKC150706
|
P09917 |
Polyunsaturated fatty acid 5-lipoxygenase |
None |
>62 |
% |
Activity |
TKC087988
|
P0DMS8 |
Adenosine receptor A3 |
None |
2357 |
nM |
Ki |
TKC096012
|
P0DMS8 |
Adenosine receptor A3 |
None |
2982 |
nM |
Ki |
TKC205544
|
P0DMS8 |
Adenosine receptor A3 |
None |
95 |
nM |
IC50 |
TKC206779
|
P0DMS8 |
Adenosine receptor A3 |
None |
2674 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
170 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
260 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
440 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
440 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
1191 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
450 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
600 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
420 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
10100 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
4800 |
nM |
Kd |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
2110 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
558 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC134945
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
1460 |
nM |
Ki |
TKC151761
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
>10000 |
nM |
GI50 |
TKC200866
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
>10000 |
nM |
GI50 |
TKC000075
|
P11473 |
Vitamin D3 receptor |
None |
70795 |
nM |
Potency |
TKC002371
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC005454
|
P11473 |
Vitamin D3 receptor |
None |
7080 |
nM |
Potency |
TKC008359
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC011412
|
P11473 |
Vitamin D3 receptor |
None |
19953 |
nM |
Potency |
TKC013736
|
P11473 |
Vitamin D3 receptor |
None |
11220 |
nM |
Potency |
TKC013755
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC013760
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC014568
|
P11473 |
Vitamin D3 receptor |
None |
63096 |
nM |
Potency |
TKC016371
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC017379
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC020031
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC020117
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC027192
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC030239
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC032619
|
P11473 |
Vitamin D3 receptor |
None |
31623 |
nM |
Potency |
TKC032913
|
P11473 |
Vitamin D3 receptor |
None |
70795 |
nM |
Potency |
TKC034083
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC034760
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC035208
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC035272
|
P11473 |
Vitamin D3 receptor |
None |
6310 |
nM |
Potency |
TKC037521
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC038268
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC038273
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC038706
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC041160
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC043519
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC053095
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC053227
|
P11473 |
Vitamin D3 receptor |
None |
14125 |
nM |
Potency |
TKC053825
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC055219
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC057133
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC062321
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC062327
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC062332
|
P11473 |
Vitamin D3 receptor |
None |
70795 |
nM |
Potency |
TKC062333
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC062669
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC066096
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC066169
|
P11473 |
Vitamin D3 receptor |
None |
7943 |
nM |
Potency |
TKC073833
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC073873
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC074866
|
P11473 |
Vitamin D3 receptor |
None |
1 |
nM |
Potency |
TKC075769
|
P11473 |
Vitamin D3 receptor |
None |
562 |
nM |
Potency |
TKC082279
|
P11473 |
Vitamin D3 receptor |
None |
70795 |
nM |
Potency |
TKC082378
|
P11473 |
Vitamin D3 receptor |
None |
25119 |
nM |
Potency |
TKC083025
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC086929
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC087533
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC087664
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC087988
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC091895
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC092297
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC092348
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC093161
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC095442
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC095452
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC096012
|
P11473 |
Vitamin D3 receptor |
None |
31623 |
nM |
Potency |
TKC097937
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC098345
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC098704
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC099703
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC100636
|
P11473 |
Vitamin D3 receptor |
None |
3981 |
nM |
Potency |
TKC100644
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC100701
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC101052
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC101598
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC102204
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC102407
|
P11473 |
Vitamin D3 receptor |
None |
15849 |
nM |
Potency |
TKC102540
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC102593
|
P11473 |
Vitamin D3 receptor |
None |
7080 |
nM |
Potency |
TKC102939
|
P11473 |
Vitamin D3 receptor |
None |
63096 |
nM |
Potency |
TKC103023
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC103159
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC103257
|
P11473 |
Vitamin D3 receptor |
None |
3162 |
nM |
Potency |
TKC103542
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC103736
|
P11473 |
Vitamin D3 receptor |
None |
3548 |
nM |
Potency |
TKC104404
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC104960
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC104961
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC105153
|
P11473 |
Vitamin D3 receptor |
None |
7943 |
nM |
Potency |
TKC105295
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC105424
|
P11473 |
Vitamin D3 receptor |
None |
19953 |
nM |
Potency |
TKC105932
|
P11473 |
Vitamin D3 receptor |
None |
63096 |
nM |
Potency |
TKC106240
|
P11473 |
Vitamin D3 receptor |
None |
>50000 |
nM |
IC50 |
TKC106250
|
P11473 |
Vitamin D3 receptor |
None |
>50000 |
nM |
IC50 |
TKC106301
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC106364
|
P11473 |
Vitamin D3 receptor |
None |
7080 |
nM |
Potency |
TKC106367
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC106426
|
P11473 |
Vitamin D3 receptor |
None |
14125 |
nM |
Potency |
TKC107086
|
P11473 |
Vitamin D3 receptor |
None |
31623 |
nM |
Potency |
TKC107332
|
P11473 |
Vitamin D3 receptor |
None |
19953 |
nM |
Potency |
TKC107625
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC107627
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC107735
|
P11473 |
Vitamin D3 receptor |
None |
17783 |
nM |
Potency |
TKC107775
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC107830
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC109619
|
P11473 |
Vitamin D3 receptor |
None |
>50000 |
nM |
IC50 |
TKC109849
|
P11473 |
Vitamin D3 receptor |
None |
>100000 |
nM |
IC50 |
TKC109996
|
P11473 |
Vitamin D3 receptor |
None |
100000 |
nM |
Potency |
TKC111464
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC112754
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC112759
|
P11473 |
Vitamin D3 receptor |
None |
70795 |
nM |
Potency |
TKC112784
|
P11473 |
Vitamin D3 receptor |
None |
19953 |
nM |
Potency |
TKC112785
|
P11473 |
Vitamin D3 receptor |
None |
>40100 |
nM |
IC50 |
TKC112787
|
P11473 |
Vitamin D3 receptor |
None |
>14500 |
nM |
IC50 |
TKC112792
|
P11473 |
Vitamin D3 receptor |
None |
28184 |
nM |
Potency |
TKC112906
|
P11473 |
Vitamin D3 receptor |
None |
25119 |
nM |
Potency |
TKC113063
|
P11473 |
Vitamin D3 receptor |
None |
5805 |
nM |
Potency |
TKC113146
|
P11473 |
Vitamin D3 receptor |
None |
39811 |
nM |
Potency |
TKC113150
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC113161
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC113663
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC114511
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC114568
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC114819
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC115268
|
P11473 |
Vitamin D3 receptor |
None |
0 |
nM |
EC50 |
TKC115284
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC115284
|
P11473 |
Vitamin D3 receptor |
None |
>2408 |
uM |
Activity |
TKC118419
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC122884
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
2 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
1 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.08 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
7.7 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.7 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.8 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
322 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.06 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.35 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
3.9 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
10 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.3 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.16 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.065 |
nM |
Kd |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
9 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.5 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.555 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
1 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
13 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
1.24 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.04 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
>0.900000 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
3 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.026 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
7.7 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
15 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
1.6 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.0953 |
nM |
IC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
0.011 |
nM |
EC50 |
TKC122892
|
P11473 |
Vitamin D3 receptor |
None |
24 |
nM |
Kd |
TKC134702
|
P11473 |
Vitamin D3 receptor |
None |
31623 |
nM |
Potency |
TKC136931
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC143885
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC147290
|
P11473 |
Vitamin D3 receptor |
None |
25119 |
nM |
Potency |
TKC147303
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC148601
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC149827
|
P11473 |
Vitamin D3 receptor |
None |
14125 |
nM |
Potency |
TKC151237
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC151571
|
P11473 |
Vitamin D3 receptor |
None |
22387 |
nM |
Potency |
TKC151609
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC151675
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC151758
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC151784
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC151885
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC174441
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC205788
|
P11473 |
Vitamin D3 receptor |
None |
0 |
nM |
ED50 |
TKC205791
|
P11473 |
Vitamin D3 receptor |
None |
1 |
nM |
IC50 |
TKC205796
|
P11473 |
Vitamin D3 receptor |
None |
631 |
nM |
Potency |
TKC205798
|
P11473 |
Vitamin D3 receptor |
None |
11 |
% |
Activity |
TKC206385
|
P11473 |
Vitamin D3 receptor |
None |
>44 |
uM |
Activity |
TKC206544
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC206652
|
P11473 |
Vitamin D3 receptor |
None |
562 |
nM |
Potency |
TKC206669
|
P11473 |
Vitamin D3 receptor |
None |
>50000 |
nM |
IC50 |
TKC206672
|
P11473 |
Vitamin D3 receptor |
None |
>50000 |
nM |
IC50 |
TKC206758
|
P11473 |
Vitamin D3 receptor |
None |
56234 |
nM |
Potency |
TKC206760
|
P11473 |
Vitamin D3 receptor |
None |
8913 |
nM |
Potency |
TKC206760
|
P11473 |
Vitamin D3 receptor |
None |
6 |
% |
Activity |
TKC206760
|
P11473 |
Vitamin D3 receptor |
None |
330 |
nM |
Kd |
TKC206761
|
P11473 |
Vitamin D3 receptor |
None |
>15100 |
nM |
IC50 |
TKC206780
|
P11473 |
Vitamin D3 receptor |
None |
89125 |
nM |
Potency |
TKC206812
|
P11473 |
Vitamin D3 receptor |
None |
44668 |
nM |
Potency |
TKC206812
|
P11473 |
Vitamin D3 receptor |
None |
2000 |
nM |
IC50 |
TKC206816
|
P11473 |
Vitamin D3 receptor |
None |
15849 |
nM |
Potency |
TKC206876
|
P11473 |
Vitamin D3 receptor |
None |
79433 |
nM |
Potency |
TKC206884
|
P11473 |
Vitamin D3 receptor |
None |
50119 |
nM |
Potency |
TKC206884
|
P11473 |
Vitamin D3 receptor |
None |
>150000 |
nM |
EC50 |
TKC206901
|
P11473 |
Vitamin D3 receptor |
None |
31623 |
nM |
Potency |
TKC206902
|
P11473 |
Vitamin D3 receptor |
None |
35481 |
nM |
Potency |
TKC206960
|
P11473 |
Vitamin D3 receptor |
None |
17783 |
nM |
Potency |
TKC021325
|
P11509 |
Cytochrome P450 2A6 |
None |
840 |
nM |
Ki |
TKC021325
|
P11509 |
Cytochrome P450 2A6 |
None |
2000 |
nM |
Ki |
TKC021332
|
P11509 |
Cytochrome P450 2A6 |
None |
840 |
nM |
Ki |
TKC039868
|
P11509 |
Cytochrome P450 2A6 |
None |
15 |
% |
Drug metabolism |
TKC110956
|
P11509 |
Cytochrome P450 2A6 |
None |
<0 |
pmol/min |
Drug metabolism |
TKC026583
|
P11802 |
Cyclin-dependent kinase 4 |
None |
9 |
ug.mL-1 |
IC50 |
TKC113582
|
P11802 |
Cyclin-dependent kinase 4 |
None |
10 |
ug.mL-1 |
IC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
1 |
nM |
Kd |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
148 |
nM |
Kd |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
45 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
74 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
6 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
12 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
45 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
1 |
nM |
Ki |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
148 |
nM |
Kd |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
6 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
4 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
6 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
45 |
nM |
EC50 |
TKC013755
|
P13631 |
Retinoic acid receptor gamma |
None |
22 |
nM |
Kd |
TKC092297
|
P13631 |
Retinoic acid receptor gamma |
None |
>400 |
nM |
Ki |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0 |
nM |
Ki |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
6 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
16 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
19 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
IC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
19 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
33 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
20 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.5 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
8 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.3 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
10 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
3 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.5 |
nM |
IC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.62 |
nM |
IC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.7 |
nM |
Ki |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.2 |
nM |
Kd |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.2 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.5 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.5 |
nM |
Ki |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
10 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.5 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
0.6 |
nM |
Ki |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
15 |
nM |
EC50 |
TKC096012
|
P13631 |
Retinoic acid receptor gamma |
None |
18 |
nM |
Kd |
TKC206482
|
P13631 |
Retinoic acid receptor gamma |
None |
6 |
nM |
EC50 |
TKC206812
|
P13631 |
Retinoic acid receptor gamma |
None |
>100000 |
nM |
EC50 |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
687 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
280 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
398.1 |
nM |
Ki |
TKC206544
|
P14416 |
D(2) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC003173
|
P20701 |
Integrin alpha-L |
None |
50000 |
nM |
IC50 |
TKC062636
|
P20701 |
Integrin alpha-L |
None |
1360 |
nM |
IC50 |
TKC062646
|
P20701 |
Integrin alpha-L |
None |
>50000 |
nM |
IC50 |
TKC062669
|
P20701 |
Integrin alpha-L |
None |
950 |
nM |
IC50 |
TKC062671
|
P20701 |
Integrin alpha-L |
None |
180 |
nM |
IC50 |
TKC089595
|
P20701 |
Integrin alpha-L |
None |
25 |
ug.mL-1 |
IC50 |
TKC093960
|
P20701 |
Integrin alpha-L |
None |
25 |
ug.mL-1 |
IC50 |
TKC103159
|
P20701 |
Integrin alpha-L |
None |
300 |
nM |
IC50 |
TKC105374
|
P20701 |
Integrin alpha-L |
None |
>50000 |
nM |
IC50 |
TKC156472
|
P20701 |
Integrin alpha-L |
None |
25 |
ug.mL-1 |
IC50 |
TKC039202
|
P21453 |
Sphingosine 1-phosphate receptor 1 |
None |
4962 |
nM |
IC50 |
TKC096012
|
P21453 |
Sphingosine 1-phosphate receptor 1 |
None |
34120 |
nM |
EC50 |
TKC096012
|
P21453 |
Sphingosine 1-phosphate receptor 1 |
None |
>95100 |
nM |
EC50 |
TKC096012
|
P21453 |
Sphingosine 1-phosphate receptor 1 |
None |
25400 |
nM |
EC50 |
TKC066433
|
P22001 |
Potassium voltage-gated channel subfamily A member 3 |
None |
100 |
nM |
Kd |
TKC107279
|
P22001 |
Potassium voltage-gated channel subfamily A member 3 |
None |
100 |
nM |
IC50 |
TKC007073
|
P25105 |
Platelet-activating factor receptor |
None |
5 |
uM |
Binding affinity |
TKC105026
|
P25105 |
Platelet-activating factor receptor |
None |
575 |
nM |
IC50 |
TKC105028
|
P25105 |
Platelet-activating factor receptor |
None |
575 |
nM |
IC50 |
TKC106540
|
P25105 |
Platelet-activating factor receptor |
None |
964 |
nM |
Ki |
TKC147486
|
P25105 |
Platelet-activating factor receptor |
None |
4 |
uM |
Binding affinity |
TKC147612
|
P25105 |
Platelet-activating factor receptor |
None |
5 |
uM |
Binding affinity |
TKC151784
|
P25105 |
Platelet-activating factor receptor |
None |
128 |
nM |
IC50 |
TKC205457
|
P25105 |
Platelet-activating factor receptor |
None |
1259 |
nM |
IC50 |
TKC113091
|
P27487 |
Dipeptidyl peptidase 4 |
None |
35600 |
nM |
IC50 |
TKC122980
|
P27487 |
Dipeptidyl peptidase 4 |
None |
28840 |
nM |
IC50 |
TKC123088
|
P27487 |
Dipeptidyl peptidase 4 |
None |
55820 |
nM |
IC50 |
TKC206549
|
P35869 |
Aryl hydrocarbon receptor |
None |
17783 |
nM |
Potency |
TKC003060
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC005454
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4600 |
nM |
IC50 |
TKC016414
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>10000 |
nM |
EC50 |
TKC020636
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
6900 |
nM |
IC50 |
TKC020796
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
22900 |
nM |
IC50 |
TKC020867
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
26 |
% |
Inhibition |
TKC020868
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
31 |
% |
Inhibition |
TKC020869
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
49 |
% |
Inhibition |
TKC022393
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
89500 |
nM |
IC50 |
TKC022771
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC028367
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4100 |
nM |
IC50 |
TKC030728
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC033506
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2400 |
nM |
IC50 |
TKC033507
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2300 |
nM |
IC50 |
TKC036334
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC038766
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1 |
% |
Inhibition |
TKC039282
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC042554
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
6300 |
nM |
IC50 |
TKC042556
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
110000 |
nM |
IC50 |
TKC044507
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC044595
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC044621
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
3 |
% |
Inhibition |
TKC044669
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC047957
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
17100 |
nM |
IC50 |
TKC047959
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC047961
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC048029
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
270 |
nM |
IC50 |
TKC048030
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
19200 |
nM |
IC50 |
TKC048031
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
590 |
nM |
IC50 |
TKC051029
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
60000 |
nM |
MIC |
TKC060882
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>25000 |
nM |
IC50 |
TKC075769
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1862 |
nM |
IC50 |
TKC077689
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC078334
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC087623
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC087625
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
7000 |
nM |
IC50 |
TKC093311
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC100739
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC101161
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC103159
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
3000 |
nM |
IC50 |
TKC103189
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
32500 |
nM |
IC50 |
TKC103191
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
24800 |
nM |
IC50 |
TKC105152
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC107659
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC108773
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC112576
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1154 |
nM |
IC50 |
TKC134761
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
48 |
% |
Inhibition |
TKC135961
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
73000 |
nM |
IC50 |
TKC135978
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
14210 |
nM |
IC50 |
TKC136653
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC148207
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
15840 |
nM |
IC50 |
TKC149924
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
74 |
% |
Inhibition |
TKC151284
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
14000 |
nM |
IC50 |
TKC156528
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC206318
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
12200 |
nM |
IC50 |
TKC206468
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
46 |
% |
Inhibition |
TKC206627
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC206646
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
67000 |
nM |
IC50 |
TKC206652
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
700 |
nM |
IC50 |
TKC013304
|
P51449 |
Nuclear receptor ROR-gamma |
None |
66824 |
nM |
Potency |
TKC013753
|
P51449 |
Nuclear receptor ROR-gamma |
None |
29849 |
nM |
Potency |
TKC013755
|
P51449 |
Nuclear receptor ROR-gamma |
None |
14000 |
nM |
EC50 |
TKC021977
|
P51449 |
Nuclear receptor ROR-gamma |
None |
42163 |
nM |
Potency |
TKC022931
|
P51449 |
Nuclear receptor ROR-gamma |
None |
84 |
nM |
Potency |
TKC056482
|
P51449 |
Nuclear receptor ROR-gamma |
None |
130 |
nM |
IC50 |
TKC066169
|
P51449 |
Nuclear receptor ROR-gamma |
None |
33492 |
nM |
Potency |
TKC075769
|
P51449 |
Nuclear receptor ROR-gamma |
None |
1980 |
nM |
IC50 |
TKC075769
|
P51449 |
Nuclear receptor ROR-gamma |
None |
109 |
nM |
Kd |
TKC075769
|
P51449 |
Nuclear receptor ROR-gamma |
None |
2000 |
nM |
IC50 |
TKC083807
|
P51449 |
Nuclear receptor ROR-gamma |
None |
10591 |
nM |
Potency |
TKC087664
|
P51449 |
Nuclear receptor ROR-gamma |
None |
47308 |
nM |
Potency |
TKC087991
|
P51449 |
Nuclear receptor ROR-gamma |
None |
21132 |
nM |
Potency |
TKC088230
|
P51449 |
Nuclear receptor ROR-gamma |
None |
1333 |
nM |
Potency |
TKC088231
|
P51449 |
Nuclear receptor ROR-gamma |
None |
23710 |
nM |
Potency |
TKC092297
|
P51449 |
Nuclear receptor ROR-gamma |
None |
26603 |
nM |
Potency |
TKC096012
|
P51449 |
Nuclear receptor ROR-gamma |
None |
200 |
nM |
IC50 |
TKC096012
|
P51449 |
Nuclear receptor ROR-gamma |
None |
18000 |
nM |
EC50 |
TKC097944
|
P51449 |
Nuclear receptor ROR-gamma |
None |
4216 |
nM |
Potency |
TKC102407
|
P51449 |
Nuclear receptor ROR-gamma |
None |
21132 |
nM |
Potency |
TKC107086
|
P51449 |
Nuclear receptor ROR-gamma |
None |
3758 |
nM |
Potency |
TKC115268
|
P51449 |
Nuclear receptor ROR-gamma |
None |
37578 |
nM |
Potency |
TKC118648
|
P51449 |
Nuclear receptor ROR-gamma |
None |
80 |
nM |
EC50 |
TKC118652
|
P51449 |
Nuclear receptor ROR-gamma |
None |
110 |
nM |
EC50 |
TKC118929
|
P51449 |
Nuclear receptor ROR-gamma |
None |
10 |
nM |
Ki |
TKC118938
|
P51449 |
Nuclear receptor ROR-gamma |
None |
10 |
nM |
Ki |
TKC122884
|
P51449 |
Nuclear receptor ROR-gamma |
None |
20 |
nM |
EC50 |
TKC136411
|
P51449 |
Nuclear receptor ROR-gamma |
None |
37578 |
nM |
Potency |
TKC151274
|
P51449 |
Nuclear receptor ROR-gamma |
None |
60 |
nM |
Potency |
TKC206457
|
P51449 |
Nuclear receptor ROR-gamma |
None |
20 |
nM |
EC50 |
TKC206457
|
P51449 |
Nuclear receptor ROR-gamma |
None |
20 |
nM |
EC50 |
TKC206457
|
P51449 |
Nuclear receptor ROR-gamma |
None |
20 |
nM |
EC50 |
TKC206458
|
P51449 |
Nuclear receptor ROR-gamma |
None |
20 |
nM |
EC50 |
TKC206459
|
P51449 |
Nuclear receptor ROR-gamma |
None |
7 |
degrees C |
T |
TKC206672
|
P51449 |
Nuclear receptor ROR-gamma |
None |
42163 |
nM |
Potency |
TKC206688
|
P51449 |
Nuclear receptor ROR-gamma |
None |
23710 |
nM |
Potency |
TKC206759
|
P51449 |
Nuclear receptor ROR-gamma |
None |
26603 |
nM |
Potency |
TKC206760
|
P51449 |
Nuclear receptor ROR-gamma |
None |
74978 |
nM |
Potency |
TKC206770
|
P51449 |
Nuclear receptor ROR-gamma |
None |
33492 |
nM |
Potency |
TKC206812
|
P51449 |
Nuclear receptor ROR-gamma |
None |
47308 |
nM |
Potency |
TKC206816
|
P51449 |
Nuclear receptor ROR-gamma |
None |
8413 |
nM |
Potency |
TKC206915
|
P51449 |
Nuclear receptor ROR-gamma |
None |
10 |
nM |
Ki |
TKC205544
|
P51685 |
C-C chemokine receptor type 8 |
None |
5 |
% |
Inhibition |
TKC009486
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>100 |
nM |
IC50 |
TKC009499
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>100 |
nM |
IC50 |
TKC011761
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
100 |
nM |
IC50 |
TKC031094
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>25 |
% |
Inhibition |
TKC107626
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
25 |
% |
Inhibition |
TKC120591
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>100 |
nM |
IC50 |
TKC120592
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>100 |
nM |
IC50 |
TKC120593
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
>100 |
nM |
IC50 |
TKC134702
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
25 |
% |
Inhibition |
TKC151713
|
P52333 |
Tyrosine-protein kinase JAK3 |
None |
25 |
% |
Inhibition |
TKC118419
|
P53778 |
Mitogen-activated protein kinase 12 |
None |
75 |
% |
Inhibition |
TKC016794
|
P55085 |
Proteinase-activated receptor 2 |
None |
14 |
nM |
IC50 |
TKC205544
|
P61073 |
C-X-C chemokine receptor type 4 |
None |
21 |
% |
Inhibition |
TKC051063
|
Q08499 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
None |
>20000 |
nM |
IC50 |
TKC104905
|
Q08499 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
None |
245 |
nM |
IC50 |
TKC104906
|
Q08499 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
None |
542 |
nM |
IC50 |
TKC146367
|
Q08499 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
None |
>20000 |
nM |
IC50 |
TKC023254
|
Q15722 |
Leukotriene B4 receptor 1 |
None |
44500 |
nM |
IC50 |
TKC118419
|
Q15759 |
Mitogen-activated protein kinase 11 |
None |
74 |
% |
Inhibition |
TKC087988
|
Q16539 |
Mitogen-activated protein kinase 14 |
None |
2529 |
nM |
IC50 |
TKC118419
|
Q16539 |
Mitogen-activated protein kinase 14 |
None |
86 |
% |
Inhibition |
TKC105649
|
Q16881 |
Thioredoxin reductase 1, cytoplasmic |
None |
280 |
nM |
Ki |
TKC066096
|
Q9NR96 |
Toll-like receptor 9 |
None |
3015 |
nM |
IC50 |
TKC076529
|
Q9NR96 |
Toll-like receptor 9 |
None |
>49739 |
nM |
IC50 |
TKC076529
|
Q9NR96 |
Toll-like receptor 9 |
None |
>49739 |
nM |
IC50 |
TKC082378
|
Q9NR96 |
Toll-like receptor 9 |
None |
7929 |
nM |
IC50 |
TKC082378
|
Q9NR96 |
Toll-like receptor 9 |
None |
7929 |
nM |
IC50 |