Basic Information

Terpenoid ID TKC009486
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC009486 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 60000.0 nM IC50 C27677
TKC009486 Jurkat JURKAT; JM; JM-Jurkat; Jurkat-FHCRC; Jurkat FHCRC; FHCRC-11; FHCRC subclone 11; FCCH1024 21600.0 nM IC50 C7953 Orphanet_99861
TKC009486 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 52200.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC009486 P0C6X7 Replicase polyprotein 1ab rep 163200 nM IC50
TKC009486 P0C6X7 Replicase polyprotein 1ab rep 163200 nM IC50
TKC009486 P52333 Tyrosine-protein kinase JAK3 JAK3 >100 nM IC50
TKC009486 Q15046 Lysine--tRNA ligase KARS1 34 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P52333 JAK3_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P52333 JAK3_HUMAN Psoriasis [ICD-11: EA90]
P52333 JAK3_HUMAN Alopecia [ICD-11: ED70]
P52333 JAK3_HUMAN Asthma [ICD-11: CA23]
P52333 JAK3_HUMAN Crohn disease [ICD-11: DD70]
P52333 JAK3_HUMAN Acquired hypomelanotic disorder [ICD-11: ED63]
P52333 JAK3_HUMAN Atopic eczema [ICD-11: EA80]
P52333 JAK3_HUMAN B-cell lymphoma [ICD-11: 2A86]
P52333 JAK3_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P52333 JAK3_HUMAN Pruritus [ICD-11: EC90]
P52333 JAK3_HUMAN Multiple myeloma [ICD-11: 2A83]
P52333 JAK3_HUMAN Transplant rejection [ICD-11: NE84]
P52333 JAK3_HUMAN Diabetes mellitus [ICD-11: 5A10]
P52333 JAK3_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P52333 JAK3_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]