Basic Information

Terpenoid ID TKC101598
Cell line 0
Protein target 14
DiseaseNCIT 0
ORDO 0
ICD 36

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC101598 HEK293 141.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC101598 P11473 Vitamin D3 receptor VDR 56234 nM Potency
TKC101598 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 10 nM Potency
TKC101598 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 103 nM Potency
TKC101598 P84022 Mothers against decapentaplegic homolog 3 SMAD3 17783 nM Potency
TKC101598 Q06710 Paired box protein Pax-8 PAX8 <260 nM AC50
TKC101598 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 164 nM Potency
TKC101598 Q99700 Ataxin-2 ATXN2 47444 nM Potency
TKC101598 Q9UNA4 DNA polymerase iota POLI 100000 nM Potency
TKC101598 O75496 Geminin GMNN 5 nM Potency
TKC101598 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 14575 nM Potency
TKC101598 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 89125 nM Potency
TKC101598 P51450 Nuclear receptor ROR-gamma Rorc 11220 nM Potency
TKC101598 O15118 NPC intracellular cholesterol transporter 1 NPC1 126 nM Potency
TKC101598 P51151 Ras-related protein Rab-9A RAB9A 89 nM Potency
TKC101598 O43521 Bcl-2-like protein 11 BCL2L11 >350000 nM EC50
TKC101598 P38532 Heat shock factor protein 1 Hsf1 69513 nM AC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]