Basic Information

Terpenoid ID TKC206915
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206915 LAMA-84 Lama-84; LAMA84; Lama84 4300.0 nM IC50 C3174 Orphanet_521
TKC206915 HT-29 HT 29; HT29 6400.0 nM IC50 C4349
TKC206915 BJ 20000.0 nM IC50
TKC206915 A549 13600.0 nM IC50 C3512
TKC206915 PC-3 PC3; PC.3 21900.0 nM IC50 C4863
TKC206915 HepG2 14600.0 nM IC50 C3728 Orphanet_449
TKC206915 MCF7 8700.0 nM IC50 C4194
TKC206915 SH-SY5Y SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental 16400.0 nM IC50 C3270 Orphanet_635
TKC206915 C6 C-6; C 6; RGC-6; RGC6; RGc6 15000.0 nM IC50 C64069

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206915 P51449 Nuclear receptor ROR-gamma RORC 10 nM Ki
TKC206915 P35398 Nuclear receptor ROR-alpha RORA 12 nM Ki
TKC206915 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 NPC1L1 3400 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35398 RORA_HUMAN Liver cancer [ICD-11: 2C12]
P35398 RORA_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q9UHC9 NPCL1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]