Basic Information

Terpenoid ID TKC034760
Cell line 0
Protein target 13
DiseaseNCIT 0
ORDO 0
ICD 55

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC034760 A-431 A431; A431/P 5000.0 nM IC50 C4819
TKC034760 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 8000.0 nM IC50 C21604
TKC034760 HUVEC HUV-EC-C; HUVEC 1.0 nM EC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC034760 P00352 Retinal dehydrogenase 1 ALDH1A1 22387 nM Potency
TKC034760 P10636 Microtubule-associated protein tau MAPT 17783 nM Potency
TKC034760 P11473 Vitamin D3 receptor VDR 35481 nM Potency
TKC034760 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1884 nM Potency
TKC034760 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 13685 nM Potency
TKC034760 Q9UBT6 DNA polymerase kappa POLK 39811 nM Potency
TKC034760 O42275 Acetylcholinesterase ache -9 % Inhibition
TKC034760 P0DTD1 Replicase polyprotein 1ab rep -2 % Inhibition
TKC034760 P81908 Cholinesterase BCHE -3 % Inhibition
TKC034760 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 22387 nM Potency
TKC034760 O00255 Menin MEN1 39811 nM Potency
TKC034760 P02791 Ferritin light chain FTL 39811 nM Potency
TKC034760 P25779 Cruzipain 10000 nM Potency
TKC034760 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 39811 nM Potency
TKC034760 Q03181 Peroxisome proliferator-activated receptor delta PPARD 50119 nM Potency
TKC034760 P0AE18 Methionine aminopeptidase map >100000 nM IC50
TKC034760 P50579 Methionine aminopeptidase 2 METAP2 1 nM IC50
TKC034760 Q01662 Methionine aminopeptidase 1 MAP1 >100000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
Q03181 PPARD_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q03181 PPARD_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q03181 PPARD_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q03181 PPARD_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q03181 PPARD_HUMAN Obesity [ICD-11: 5B80-5B81]
Q03181 PPARD_HUMAN Alzheimer disease [ICD-11: 8A20]
Q03181 PPARD_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
Q03181 PPARD_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
Q03181 PPARD_HUMAN Diabetes mellitus [ICD-11: 5A10]
Q03181 PPARD_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P50579 MAP2_HUMAN Obesity [ICD-11: 5B80-5B81]
P50579 MAP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P50579 MAP2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P50579 MAP2_HUMAN Diabetes mellitus [ICD-11: 5A10]