Basic Information

Terpenoid ID TKC151885
Chirality TKC001229
Cell line 0
Protein target 31
DiseaseNCIT 0
ORDO 0
ICD 34

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC151885 P11473 Vitamin D3 receptor VDR 89125 nM Potency
TKC151885 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 5174 nM Potency
TKC151885 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 31623 nM Potency
TKC151885 P53350 Serine/threonine-protein kinase PLK1 PLK1 6702 nM Potency
TKC151885 P84022 Mothers against decapentaplegic homolog 3 SMAD3 12589 nM Potency
TKC151885 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 56234 nM Potency
TKC151885 Q99700 Ataxin-2 ATXN2 31623 nM Potency
TKC151885 O75164 Lysine-specific demethylase 4A KDM4A 39811 nM Potency
TKC151885 Q962Y6 Thioredoxin glutathione reductase TGR 2818 nM Potency
TKC151885 O75496 Geminin GMNN 731 nM Potency
TKC151885 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 15849 nM Potency
TKC151885 P37840 Alpha-synuclein SNCA 25119 nM Potency
TKC151885 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 22387 nM Potency
TKC151885 P39748 Flap endonuclease 1 FEN1 89125 nM Potency
TKC151885 P83916 Chromobox protein homolog 1 CBX1 22387 nM Potency
TKC151885 P00811 Beta-lactamase ampC 44668 nM Potency
TKC151885 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 891 nM Potency
TKC151885 P08659 Luciferin 4-monooxygenase 19012 nM Potency
TKC151885 O00255 Menin MEN1 12589 nM Potency
TKC151885 O97447 Putative fructose-1,6-bisphosphate aldolase fba 5012 nM Potency
TKC151885 P02791 Ferritin light chain FTL 15849 nM Potency
TKC151885 Q92830 Histone acetyltransferase KAT2A KAT2A 39811 nM Potency
TKC151885 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 3981 nM Potency
TKC151885 P29990 Genome polyprotein 84430 nM IC50
TKC151885 P49798 Regulator of G-protein signaling 4 RGS4 44668 nM Potency
TKC151885 P51450 Nuclear receptor ROR-gamma Rorc 14125 nM Potency
TKC151885 Q27686 Pyruvate kinase PYK 15849 nM Potency
TKC151885 P06492 Tegument protein VP16 UL48 39892 nM IC50
TKC151885 Q9Y5X4 Photoreceptor-specific nuclear receptor NR2E3 2594 nM IC50
TKC151885 P11413 Glucose-6-phosphate 1-dehydrogenase G6PD >80000 nM IC50
TKC151885 Q57TT1 HpcH_HpaI domain-containing protein Tb08.30K1.730 2239 nM Potency
TKC151885 Q9BHT9 Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase G6PD-6PGL 4950 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P53350 PLK1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P53350 PLK1_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P53350 PLK1_HUMAN Prostate cancer [ICD-11: 2C82]
P53350 PLK1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P53350 PLK1_HUMAN Pancreatic cancer [ICD-11: 2C10]
P53350 PLK1_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P53350 PLK1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11413 G6PD_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11413 G6PD_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P11413 G6PD_HUMAN Rheumatoid arthritis [ICD-11: FA20]