Basic Information

Terpenoid ID TKC001229
Chirality TKC151885
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 22

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC001229 MCF7 40900.0 nM IC50 C4194
TKC001229 A2780 A-2780; 2780; A2780S; A2780par 3600.0 nM GI50 C7979 Orphanet_454723
TKC001229 SW1573 SW-1573; SW 1573 10000.0 nM GI50 C2923
TKC001229 WiDr WiDR; WIDR; WiDr/S; WiDr-TC; WiDrTC; LED-WiDr; Led-WiDr 26000.0 nM GI50 C4349
TKC001229 T47D 24000.0 nM GI50 C4194
TKC001229 HBL-100 HBL 100; HBL100 3900.0 nM GI50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC001229 O14684 Prostaglandin E synthase PTGES 5000 nM IC50
TKC001229 P14324 Farnesyl pyrophosphate synthase FDPS 13300 nM IC50
TKC001229 P16233 Pancreatic triacylglycerol lipase PNLIP 13000 nM IC50
TKC001229 Q72874 Protease pol >10 ug.mL-1 IC90

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O14684 PTGES_HUMAN Alzheimer disease [ICD-11: 8A20]
O14684 PTGES_HUMAN Circulatory system disease [ICD-11: BE2Z]
O14684 PTGES_HUMAN Joint pain [ICD-11: ME82]
O14684 PTGES_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P14324 FPPS_HUMAN Bone paget disease [ICD-11: FB85]
P14324 FPPS_HUMAN Focal/segmental autonomic disorder [ICD-11: 8D8A]
P14324 FPPS_HUMAN Low bone mass disorder [ICD-11: FB83]
P14324 FPPS_HUMAN Mineral excesses [ICD-11: 5B91]
P14324 FPPS_HUMAN Musculoskeletal system/connective tissue disease [ICD-11: FC0Z]
P14324 FPPS_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P14324 FPPS_HUMAN Colorectal cancer [ICD-11: 2B91]
P14324 FPPS_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P14324 FPPS_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P14324 FPPS_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
P14324 FPPS_HUMAN Pancreatic cancer [ICD-11: 2C10]
P14324 FPPS_HUMAN Sexually transmitted infection [ICD-11: 1A9Y-1A9Z]
P14324 FPPS_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P16233 LIPP_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P16233 LIPP_HUMAN Obesity [ICD-11: 5B80-5B81]
P16233 LIPP_HUMAN Pancreatic malfunction [ICD-11: DC30-DC3Z]
P16233 LIPP_HUMAN Cystic fibrosis [ICD-11: CA25]
P16233 LIPP_HUMAN Pancreas disease [ICD-11: DC35-DC3Z]