Basic Information

Terpenoid ID TKC086929
Chirality TKC085168
Cell line 0
Protein target 8
DiseaseNCIT 0
ORDO 0
ICD 33

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC086929 P11473 Vitamin D3 receptor VDR 39811 nM Potency
TKC086929 Q01196 Runt-related transcription factor 1 RUNX1 31623 nM Potency
TKC086929 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 226 % Activity
TKC086929 O75762 Transient receptor potential cation channel subfamily A member 1 TRPA1 28400 nM EC50
TKC086929 O75762 Transient receptor potential cation channel subfamily A member 1 TRPA1 31623 nM EC50
TKC086929 Q96RI1 Bile acid receptor NR1H4 2 nM Potency
TKC086929 P0DTE4 UDP-glucuronosyltransferase 2A1 UGT2A1 97 pm/min/mg Activity
TKC086929 P22309 UDP-glucuronosyltransferase 1A1 UGT1A1 0 pm/min/mg Activity
TKC086929 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 39 pm/min/mg Activity
TKC086929 Q75NA5 Gamma-aminobutyric acid receptor subunit beta Rdl 80 % Activity
TKC086929 Q8R455 Transient receptor potential cation channel subfamily M member 8 Trpm8 75000 nM EC50
TKC086929 O60656 UDP-glucuronosyltransferase 1A9 UGT1A9 0 pm/min/mg Activity
TKC086929 Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 TRPM8 3000 nM EC50
TKC086929 P9WIB9 Secreted chorismate mutase Rv1885c 26380 nM IC50
TKC086929 P19224 UDP-glucuronosyltransferase 1-6 UGT1A6 0 pm/min/mg Activity
TKC086929 P35503 UDP-glucuronosyltransferase 1A3 UGT1A3 0 pm/min/mg Activity
TKC086929 P54855 UDP-glucuronosyltransferase 2B15 UGT2B15 0 pm/min/mg Activity
TKC086929 Q9HAW9 UDP-glucuronosyltransferase 1A8 UGT1A8 0 pm/min/mg Activity
TKC086929 P16662 UDP-glucuronosyltransferase 2B7 UGT2B7 0 pm/min/mg Activity
TKC086929 Q8BLA8 Transient receptor potential cation channel subfamily A member 1 Trpa1 56000 nM EC50
TKC086929 Q8BLA8 Transient receptor potential cation channel subfamily A member 1 Trpa1 95000 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P14867 GBRA1_HUMAN Acute respiratory distress syndrome [ICD-11: CB00]
P14867 GBRA1_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P14867 GBRA1_HUMAN Chronic insomnia [ICD-11: 7A00]
P14867 GBRA1_HUMAN Chronic pain [ICD-11: MG30]
P14867 GBRA1_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P14867 GBRA1_HUMAN Cystitis [ICD-11: GC00]
P14867 GBRA1_HUMAN Depression [ICD-11: 6A70-6A7Z]
P14867 GBRA1_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
P14867 GBRA1_HUMAN Headache [ICD-11: 8A80-8A84]
P14867 GBRA1_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P14867 GBRA1_HUMAN Liver vascular disorder [ICD-11: DB98]
P14867 GBRA1_HUMAN Malaria [ICD-11: 1F40-1F45]
P14867 GBRA1_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
P14867 GBRA1_HUMAN Status epilepticus [ICD-11: 8A66]
P14867 GBRA1_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P14867 GBRA1_HUMAN Tremor-related disorder [ICD-11: 8A04]
P14867 GBRA1_HUMAN Indeterminate colitis [ICD-11: DD72]
P14867 GBRA1_HUMAN Female pelvic pain [ICD-11: GA34]
P14867 GBRA1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
O75762 TRPA1_HUMAN Upper respiratory tract disorder [ICD-11: CA0Z]
O75762 TRPA1_HUMAN Neuropathy [ICD-11: 8C0Z]
O75762 TRPA1_HUMAN Pain [ICD-11: MG30-MG3Z]
O75762 TRPA1_HUMAN Upper respiratory tract disorder [ICD-11: CA0Z]
O75762 TRPA1_HUMAN Neuropathy [ICD-11: 8C0Z]
O75762 TRPA1_HUMAN Pain [ICD-11: MG30-MG3Z]
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P22309 UD11_HUMAN Inborn porphyrin/heme metabolism error [ICD-11: 5C58]
Q7Z2W7 TRPM8_HUMAN Upper respiratory tract disorder [ICD-11: CA0Z]
Q7Z2W7 TRPM8_HUMAN Pain [ICD-11: MG30-MG3Z]
Q7Z2W7 TRPM8_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q7Z2W7 TRPM8_HUMAN General pain disorder [ICD-11: 8E43]