Basic Information

Terpenoid ID TKC051021
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 46

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC051021 3T3-L1 3T3 L1; 3T3L1; 3T3-L1 ad; NIH-3T3-L1; NIH3T3-L1 22.0 % Inhibition
TKC051021 SGC-7901 SGC 7901; SGC7901 7250.0 nM IC50 C27677
TKC051021 Bel-7402 Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 7250.0 nM IC50 C27677
TKC051021 P388 P-388 7250.0 nM IC50 C21602
TKC051021 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 202000.0 nM IC50 C27677
TKC051021 HepG2 97400.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC051021 P06276 Cholinesterase BCHE >200000 nM IC50
TKC051021 P22303 Acetylcholinesterase ACHE 22630 nM IC50
TKC051021 P15121 Aldo-keto reductase family 1 member B1 AKR1B1 >193500 nM IC50
TKC051021 P01375 Tumor necrosis factor TNF 9 nM Kd

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P06276 CHLE_HUMAN Pain [ICD-11: MG30-MG3Z]
P06276 CHLE_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P06276 CHLE_HUMAN Alzheimer disease [ICD-11: 8A20]
P06276 CHLE_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P06276 CHLE_HUMAN Eexposure to noxious substances harmful effect [ICD-11: NE61]
P06276 CHLE_HUMAN Toxicity [ICD-11: N.A.]
P06276 CHLE_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Alzheimer disease [ICD-11: 8A20]
P22303 ACES_HUMAN Glaucoma [ICD-11: 9C61]
P22303 ACES_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P22303 ACES_HUMAN Oesophageal/gastroduodenal disorder [ICD-11: DD90]
P22303 ACES_HUMAN Pediculosis [ICD-11: 1G00]
P22303 ACES_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P22303 ACES_HUMAN Parasitic worm infestation [ICD-11: 1F90]
P22303 ACES_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P22303 ACES_HUMAN Pain [ICD-11: MG30-MG3Z]
P22303 ACES_HUMAN Parkinsonism [ICD-11: 8A00]
P22303 ACES_HUMAN Substance abuse [ICD-11: 6C40]
P22303 ACES_HUMAN Lips/oral mucosa miscellaneous disorder [ICD-11: DA02]
P22303 ACES_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P22303 ACES_HUMAN Urinary system disease [ICD-11: GC2Z]
P22303 ACES_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P15121 ALDR_HUMAN Neuropathy [ICD-11: 8C0Z]
P15121 ALDR_HUMAN Pain [ICD-11: MG30-MG3Z]
P15121 ALDR_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P15121 ALDR_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P15121 ALDR_HUMAN Thrombosis [ICD-11: DB61-GB90]
P15121 ALDR_HUMAN Cataract [ICD-11: 9B10]
P15121 ALDR_HUMAN Glaucoma [ICD-11: 9C61]
P15121 ALDR_HUMAN Schizophrenia [ICD-11: 6A20]
P15121 ALDR_HUMAN Gout [ICD-11: FA25]
P15121 ALDR_HUMAN Head and neck cancer [ICD-11: 2D42]
P01375 TNFA_HUMAN Crohn disease [ICD-11: DD70]
P01375 TNFA_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P01375 TNFA_HUMAN Schizophrenia [ICD-11: 6A20]
P01375 TNFA_HUMAN Arterial occlusive disease [ICD-11: BD40]
P01375 TNFA_HUMAN Asthma [ICD-11: CA23]
P01375 TNFA_HUMAN Indeterminate colitis [ICD-11: DD72]
P01375 TNFA_HUMAN Multiple myeloma [ICD-11: 2A83]
P01375 TNFA_HUMAN Pancreatitis [ICD-11: DC31-DC34]
P01375 TNFA_HUMAN Pemphigus [ICD-11: EB40]
P01375 TNFA_HUMAN Psoriasis [ICD-11: EA90]
P01375 TNFA_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P01375 TNFA_HUMAN Sepsis [ICD-11: 1G40-1G41]
P01375 TNFA_HUMAN Spinal pain [ICD-11: ME84]
P01375 TNFA_HUMAN Cystic fibrosis [ICD-11: CA25]
P01375 TNFA_HUMAN Esophageal cancer [ICD-11: 2B70]
P01375 TNFA_HUMAN Lupus erythematosus [ICD-11: 4A40]
P01375 TNFA_HUMAN Systemic sclerosis [ICD-11: 4A42]
P01375 TNFA_HUMAN Atopic eczema [ICD-11: EA80]
P01375 TNFA_HUMAN Bowel habit change [ICD-11: ME05]
P01375 TNFA_HUMAN Diabetes mellitus [ICD-11: 5A10]
P01375 TNFA_HUMAN Herpes simplex infection [ICD-11: 1F00]
P01375 TNFA_HUMAN Influenza [ICD-11: 1E30-1E32]
P01375 TNFA_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P01375 TNFA_HUMAN Pneumonia [ICD-11: CA40]
P01375 TNFA_HUMAN Psoriatic arthritis [ICD-11: FA21]
P01375 TNFA_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P01375 TNFA_HUMAN Transplant rejection [ICD-11: NE84]
P01375 TNFA_HUMAN Ulcerative colitis [ICD-11: DD71]
P01375 TNFA_HUMAN Crohn disease [ICD-11: DD70]
P01375 TNFA_HUMAN Vasomotor/allergic rhinitis [ICD-11: CA08]
P01375 TNFA_HUMAN Motor neuron disease [ICD-11: 8B60]
P01375 TNFA_HUMAN Infectious gastroenteritis/colitis [ICD-11: 1A40]