Basic Information

Terpenoid ID TKC118938
Chirality TKC206917
Cell line 0
Protein target 6
DiseaseNCIT 0
ORDO 0
ICD 19

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC118938 H4 H-4 38.0 % Activity C60781 Orphanet_94

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC118938 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 2909 nM Potency
TKC118938 P49798 Regulator of G-protein signaling 4 RGS4 37686 nM Potency
TKC118938 Q13133 Oxysterols receptor LXR-alpha NR1H3 130 nM EC50
TKC118938 P51449 Nuclear receptor ROR-gamma RORC 10 nM Ki
TKC118938 P35439 Glutamate receptor ionotropic, NMDA 1 Grin1 650 nM EC50
TKC118938 Q05586 Glutamate receptor ionotropic, NMDA 1 GRIN1 150 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q05586 NMDZ1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
Q05586 NMDZ1_HUMAN HIV-infected patients with tuberculosis [ICD-11: 1B10-1B14]
Q05586 NMDZ1_HUMAN Obsessive-compulsive disorder [ICD-11: 6B20]
Q05586 NMDZ1_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q05586 NMDZ1_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
Q05586 NMDZ1_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
Q05586 NMDZ1_HUMAN Alzheimer disease [ICD-11: 8A20]
Q05586 NMDZ1_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
Q05586 NMDZ1_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]