Basic Information

Terpenoid ID TKC012492
Chirality TKC079223
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 17

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC012492 Raji RAJI; P1-Raji; GM04671 50000.0 nM IC50 C27694 Orphanet_543
TKC012492 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 75000.0 nM IC50 C9154 Orphanet_519
TKC012492 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 84.0 uM LD50 C9142 Orphanet_99861
TKC012492 BALL-1 Ball-1; Ball 1; BALL1; B-cell Acute Lymphoblastic Leukemia-1 87.0 uM LD50 C9143 Orphanet_99860
TKC012492 MCF7 2.0 ug.mL-1 IC50 C4194
TKC012492 U-937 U937; U 937 66900.0 nM LC50 C8263 Orphanet_514

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC012492 P0DTD1 Replicase polyprotein 1ab rep 10 % Inhibition
TKC012492 P00742 Coagulation factor X F10 13385 nM Ki
TKC012492 P05412 Transcription factor AP-1 JUN 3 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P00742 FA10_HUMAN Blood-forming organ disease [ICD-11: 3C0Z]
P00742 FA10_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
P00742 FA10_HUMAN Christmas disease [ICD-11: 3B11]
P00742 FA10_HUMAN Coagulation defect [ICD-11: 3B10]
P00742 FA10_HUMAN Coronary thrombosis [ICD-11: BA43]
P00742 FA10_HUMAN Deep vein thrombosis [ICD-11: BD71]
P00742 FA10_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P00742 FA10_HUMAN Thrombosis [ICD-11: DB61-GB90]
P00742 FA10_HUMAN Venous thromboembolism [ICD-11: BD72]
P00742 FA10_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P00742 FA10_HUMAN Bleeding disorder [ICD-11: GA20-GA21]
P00742 FA10_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P00742 FA10_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P00742 FA10_HUMAN Angina pectoris [ICD-11: BA40]
P00742 FA10_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P00742 FA10_HUMAN Psoriasis [ICD-11: EA90]
P00742 FA10_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P05412 JUN_HUMAN Rheumatoid arthritis [ICD-11: FA20]