Basic Information

Terpenoid ID TKC206902
Cell line 0
Protein target 6
DiseaseNCIT 0
ORDO 0
ICD 31

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206902 BGC-823 BGC823 7890.0 nM IC50 C27677
TKC206902 KB KB (HeLa derivative); HeLa-KB; Strain KB 1.0 ug.mL-1 IC50 C27677
TKC206902 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 1.0 ug.mL-1 IC50 C9154 Orphanet_519
TKC206902 MH60 MH60.BSF-2; MH60-BSF-2; MH60 10.0 ug.mL-1 IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206902 P11473 Vitamin D3 receptor VDR 35481 nM Potency
TKC206902 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 14963 nM Potency
TKC206902 P84022 Mothers against decapentaplegic homolog 3 SMAD3 7943 nM Potency
TKC206902 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 1458 nM Potency
TKC206902 O75496 Geminin GMNN 8414 nM Potency
TKC206902 P0DTD1 Replicase polyprotein 1ab rep 8 % Inhibition
TKC206902 P25094 Peripheral myelin protein 22 Pmp22 28695 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]