Basic Information

Terpenoid ID TKC093161
Chirality TKC093162
Cell line 0
Protein target 13
DiseaseNCIT 0
ORDO 0
ICD 26

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC093161 HepG2 25119.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC093161 P11473 Vitamin D3 receptor VDR 89125 nM Potency
TKC093161 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 20596 nM Potency
TKC093161 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 23109 nM Potency
TKC093161 P84022 Mothers against decapentaplegic homolog 3 SMAD3 35481 nM Potency
TKC093161 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 39811 nM Potency
TKC093161 Q99700 Ataxin-2 ATXN2 31623 nM Potency
TKC093161 O75164 Lysine-specific demethylase 4A KDM4A 79433 nM Potency
TKC093161 Q9UNA4 DNA polymerase iota POLI 12589 nM Potency
TKC093161 Q9Y253 DNA polymerase eta POLH 31623 nM Potency
TKC093161 O94925 Glutaminase kidney isoform, mitochondrial GLS 12589 nM Potency
TKC093161 O15648 ATP-dependent 6-phosphofructokinase pfk 21331 nM Potency
TKC093161 Q13324 Corticotropin-releasing factor receptor 2 CRHR2 11400 nM EC50
TKC093161 P24387 Corticotropin-releasing factor-binding protein CRHBP 11400 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
Q13324 CRFR2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q13324 CRFR2_HUMAN Binge eating disorder [ICD-11: 6B82]
Q13324 CRFR2_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]