Basic Information

Terpenoid ID TKC093162
Chirality TKC093161
Cell line 0
Protein target 15
DiseaseNCIT 0
ORDO 0
ICD 34

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC093162 HepG2 14125.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC093162 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 18356 nM Potency
TKC093162 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 18356 nM Potency
TKC093162 P43220 Glucagon-like peptide 1 receptor GLP1R 12589 nM Potency
TKC093162 P84022 Mothers against decapentaplegic homolog 3 SMAD3 14125 nM Potency
TKC093162 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 16360 nM Potency
TKC093162 Q99700 Ataxin-2 ATXN2 31623 nM Potency
TKC093162 Q9UNA4 DNA polymerase iota POLI 25119 nM Potency
TKC093162 O75496 Geminin GMNN 1458 nM Potency
TKC093162 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 79433 nM Potency
TKC093162 P83916 Chromobox protein homolog 1 CBX1 112202 nM Potency
TKC093162 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 29081 nM Potency
TKC093162 P63096 Guanine nucleotide-binding protein G GNAI1 50119 nM Potency
TKC093162 O94925 Glutaminase kidney isoform, mitochondrial GLS 22387 nM Potency
TKC093162 Q13324 Corticotropin-releasing factor receptor 2 CRHR2 5490 nM EC50
TKC093162 P24387 Corticotropin-releasing factor-binding protein CRHBP 5490 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q13324 CRFR2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q13324 CRFR2_HUMAN Binge eating disorder [ICD-11: 6B82]
Q13324 CRFR2_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]