Basic Information

Terpenoid ID TKC206457
Chirality TKC206458
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206457 Q13133 Oxysterols receptor LXR-alpha NR1H3 325 nM EC50
TKC206457 Q13133 Oxysterols receptor LXR-alpha NR1H3 >15000 nM EC50
TKC206457 Q13133 Oxysterols receptor LXR-alpha NR1H3 6710 nM EC50
TKC206457 Q13133 Oxysterols receptor LXR-alpha NR1H3 15000 nM EC50
TKC206457 Q13133 Oxysterols receptor LXR-alpha NR1H3 1000 nM EC50
TKC206457 P55055 Oxysterols receptor LXR-beta NR1H2 4750 nM EC50
TKC206457 P55055 Oxysterols receptor LXR-beta NR1H2 >15000 nM EC50
TKC206457 P55055 Oxysterols receptor LXR-beta NR1H2 15000 nM EC50
TKC206457 P51449 Nuclear receptor ROR-gamma RORC 20 nM EC50
TKC206457 P51449 Nuclear receptor ROR-gamma RORC 20 nM EC50
TKC206457 P51449 Nuclear receptor ROR-gamma RORC 20 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
P55055 NR1H2_HUMAN Atopic eczema [ICD-11: EA80]
P55055 NR1H2_HUMAN Depression [ICD-11: 6A70-6A7Z]
P55055 NR1H2_HUMAN Atopic eczema [ICD-11: EA80]
P55055 NR1H2_HUMAN Depression [ICD-11: 6A70-6A7Z]
P55055 NR1H2_HUMAN Atopic eczema [ICD-11: EA80]
P55055 NR1H2_HUMAN Depression [ICD-11: 6A70-6A7Z]
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]