Basic Information

Terpenoid ID TKC151523
Chirality TKC057187
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 9

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC151523 HepG2 35481.0 nM Potency C3728 Orphanet_449
TKC151523 PBMC 452.0 ug.mL-1 CC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC151523 P08684 Cytochrome P450 3A4 CYP3A4 23200 nM Ki
TKC151523 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 92 % Inhibition
TKC151523 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 102 % Inhibition
TKC151523 P08183 ATP-dependent translocase ABCB1 ABCB1 19140 nM IC50
TKC151523 O42275 Acetylcholinesterase ache -1 % Inhibition
TKC151523 P0DTD1 Replicase polyprotein 1ab rep -2 % Inhibition
TKC151523 P81908 Cholinesterase BCHE -14 % Inhibition
TKC151523 Q9WKE8 Reverse transcriptase reverse transcriptase >0 ug.mL-1 IC50
TKC151523 P14679 Tyrosinase TYR 4 % Inhibition
TKC151523 P08908 5-hydroxytryptamine receptor 1A HTR1A >100000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P08183 MDR1_HUMAN Lung cancer [ICD-11: 2C25]
P08183 MDR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08183 MDR1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P08183 MDR1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08183 MDR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P08183 MDR1_HUMAN Ovarian cancer [ICD-11: 2C73]
P14679 TYRO_HUMAN Acquired hypermelanosis [ICD-11: ED60]
P14679 TYRO_HUMAN Acquired hypomelanotic disorder [ICD-11: ED63]
P14679 TYRO_HUMAN Melanoma [ICD-11: 2C30]
P14679 TYRO_HUMAN Acquired melanotic macule/lentigine [ICD-11: ED61]
P14679 TYRO_HUMAN Mineral absorption/transport disorder [ICD-11: 5C64]
P14679 TYRO_HUMAN Skin pigmentation genetic disorder [ICD-11: EC23]
P14679 TYRO_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P08908 5HT1A_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P08908 5HT1A_HUMAN Depression [ICD-11: 6A70-6A7Z]
P08908 5HT1A_HUMAN Hypertension [ICD-11: BA00-BA04]
P08908 5HT1A_HUMAN Migraine [ICD-11: 8A80]
P08908 5HT1A_HUMAN Mood disorder [ICD-11: 6A60-6E23]
P08908 5HT1A_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P08908 5HT1A_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P08908 5HT1A_HUMAN Alzheimer disease [ICD-11: 8A20]
P08908 5HT1A_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P08908 5HT1A_HUMAN Juvenile idiopathic arthritis [ICD-11: FA24]
P08908 5HT1A_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P08908 5HT1A_HUMAN Muscular atrophy [ICD-11: 8B61]
P08908 5HT1A_HUMAN Parkinsonism [ICD-11: 8A00]
P08908 5HT1A_HUMAN Psoriasis [ICD-11: EA90]
P08908 5HT1A_HUMAN Schizophrenia [ICD-11: 6A20]
P08908 5HT1A_HUMAN Skin/mucosal anomaly [ICD-11: LD27]
P08908 5HT1A_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P08908 5HT1A_HUMAN Intellectual development disorder [ICD-11: LD90]
P08908 5HT1A_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P08908 5HT1A_HUMAN Bipolar disorder [ICD-11: 6A60]
P08908 5HT1A_HUMAN Bulimia nervosa [ICD-11: 6B81]
P08908 5HT1A_HUMAN Coronary atherosclerosis [ICD-11: BA80]
P08908 5HT1A_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P08908 5HT1A_HUMAN Hypoactive sexual desire dysfunction [ICD-11: HA00]
P08908 5HT1A_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P08908 5HT1A_HUMAN Psychotic disorder [ICD-11: 6A20-6A25]
P08908 5HT1A_HUMAN Social anxiety disorder [ICD-11: 6B04]
P08908 5HT1A_HUMAN Ejaculatory dysfunction [ICD-11: HA03]
P08908 5HT1A_HUMAN Prostate hyperplasia [ICD-11: GA90]
P08908 5HT1A_HUMAN Addictive disorder [ICD-11: 6C50-6C5Z]
P08908 5HT1A_HUMAN Abnormal micturition [ICD-11: MF50]
P08908 5HT1A_HUMAN Episode [ICD-11: N.A.]
P08908 5HT1A_HUMAN Dystonic disorder [ICD-11: 8A02]
P08908 5HT1A_HUMAN Post-traumatic stress disorder [ICD-11: 6B40]
P08908 5HT1A_HUMAN Binge eating disorder [ICD-11: 6B82]
P08908 5HT1A_HUMAN Pain [ICD-11: MG30-MG3Z]
P08908 5HT1A_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]