Basic Information
| Terpenoid ID | TKC136411 |
|
| Cell line | 0 | |
| Protein target | 15 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 137 |
| Terpenoid ID | TKC136411 |
|
| Cell line | 0 | |
| Protein target | 15 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 137 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC136411 | P00352 | Retinal dehydrogenase 1 | ALDH1A1 | 17783 | nM | Potency |
| TKC136411 | P11473 | Vitamin D3 receptor | VDR | 0 | Activity | |
| TKC136411 | Q16236 | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | 74978 | nM | Potency |
| TKC136411 | P04150 | Glucocorticoid receptor | NR3C1 | 1 | nM | Potency |
| TKC136411 | P37231 | Peroxisome proliferator-activated receptor gamma | PPARG | 0 | Activity | |
| TKC136411 | P10276 | Retinoic acid receptor alpha | RARA | 0 | Activity | |
| TKC136411 | P13631 | Retinoic acid receptor gamma | RARG | 0 | Activity | |
| TKC136411 | Q03181 | Peroxisome proliferator-activated receptor delta | PPARD | 31623 | nM | Potency |
| TKC136411 | Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | 0 | Activity | |
| TKC136411 | P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABRA1 | 19000 | nM | EC50 |
| TKC136411 | P55055 | Oxysterols receptor LXR-beta | NR1H2 | 0 | Activity | |
| TKC136411 | P19793 | Retinoic acid receptor RXR-alpha | RXRA | 9 | FC | |
| TKC136411 | P28702 | Retinoic acid receptor RXR-beta | RXRB | 5200 | nM | EC50 |
| TKC136411 | P48443 | Retinoic acid receptor RXR-gamma | RXRG | 43000 | nM | EC50 |
| TKC136411 | P16473 | Thyrotropin receptor | TSHR | 39811 | nM | Potency |
| TKC136411 | P10145 | Interleukin-8 | CXCL8 | 74978 | nM | Potency |
| TKC136411 | P51449 | Nuclear receptor ROR-gamma | RORC | 37578 | nM | Potency |
| TKC136411 | Q96RI1 | Bile acid receptor | NR1H4 | 0 | Activity | |
| TKC136411 | P10826 | Retinoic acid receptor beta | RARB | 0 | Activity | |
| TKC136411 | Q07869 | Peroxisome proliferator-activated receptor alpha | PPARA | 0 | Activity | |
| TKC136411 | O75469 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 | 0 | Activity | |
| TKC136411 | O09028 | Gamma-aminobutyric acid receptor subunit pi | Gabrp | -115 | pA | Activity |
| TKC136411 | Q14994 | Nuclear receptor subfamily 1 group I member 3 | NR1I3 | 0 | Activity |
| Uniport ID | Uniport Name | ICD-11 | Disease |
|---|---|---|---|
| Q16236 | NF2L2_HUMAN | ICD-11: 8A03 | disorder |
| Q16236 | NF2L2_HUMAN | ICD-11: 2C60-2C6Y | cancer |
| Q16236 | NF2L2_HUMAN | ICD-11: 9C61 | Glaucoma |
| Q16236 | NF2L2_HUMAN | ICD-11: 2C25 | cancer |
| Q16236 | NF2L2_HUMAN | ICD-11: 9B75 | degeneration |
| Q16236 | NF2L2_HUMAN | ICD-11: 2C30 | Melanoma |
| Q16236 | NF2L2_HUMAN | ICD-11: 6E20-6E8Z | disorder |
| Q16236 | NF2L2_HUMAN | ICD-11: BB01 | hypertension |
| Q16236 | NF2L2_HUMAN | ICD-11: 8B01 | haemorrhage |
| Q16236 | NF2L2_HUMAN | ICD-11: MF8Y | sympton |
| Q16236 | NF2L2_HUMAN | ICD-11: DB92 | disease |
| Q16236 | NF2L2_HUMAN | ICD-11: 5C5A | deficiency |
| Q16236 | NF2L2_HUMAN | ICD-11: 8B60 | disease |
| Q16236 | NF2L2_HUMAN | ICD-11: 8A40 | sclerosis |
| P04150 | GCR_HUMAN | ICD-11: 5A2Y | complication |
| P04150 | GCR_HUMAN | ICD-11: DD72 | colitis |
| P04150 | GCR_HUMAN | ICD-11: 8A40 | sclerosis |
| P04150 | GCR_HUMAN | ICD-11: 8C70 | dystrophy |
| P04150 | GCR_HUMAN | ICD-11: 2C82 | cancer |
| P04150 | GCR_HUMAN | ICD-11: FA20 | arthritis |
| P04150 | GCR_HUMAN | ICD-11: 5A11 | mellitus |
| P04150 | GCR_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P04150 | GCR_HUMAN | ICD-11: 4A01 | immunodeficiency |
| P04150 | GCR_HUMAN | ICD-11: 5A71 | disorder |
| P04150 | GCR_HUMAN | ICD-11: 4A80-4A8Z | disorder |
| P04150 | GCR_HUMAN | ICD-11: CA23 | Asthma |
| P04150 | GCR_HUMAN | ICD-11: EA80 | eczema |
| P04150 | GCR_HUMAN | ICD-11: CA22 | disease |
| P04150 | GCR_HUMAN | ICD-11: 5A70 | syndrome |
| P04150 | GCR_HUMAN | ICD-11: EA80-EA89 | Eczema |
| P04150 | GCR_HUMAN | ICD-11: 8A40 | sclerosis |
| P04150 | GCR_HUMAN | ICD-11: 8C70 | dystrophy |
| P04150 | GCR_HUMAN | ICD-11: DA24 | Oesophagitis |
| P04150 | GCR_HUMAN | ICD-11: 1A00-CA43 | inflammation |
| P04150 | GCR_HUMAN | ICD-11: FA20 | arthritis |
| P04150 | GCR_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P04150 | GCR_HUMAN | ICD-11: ND51 | injury |
| P04150 | GCR_HUMAN | ICD-11: CA08 | rhinitis |
| P04150 | GCR_HUMAN | ICD-11: 1F00 | infection |
| P04150 | GCR_HUMAN | ICD-11: AA00-AA13 | externa |
| P04150 | GCR_HUMAN | ICD-11: 6C40 | abuse |
| P04150 | GCR_HUMAN | ICD-11: 2C60-2C6Y | cancer |
| P04150 | GCR_HUMAN | ICD-11: 6A70-6A7Z | Depression |
| P04150 | GCR_HUMAN | ICD-11: 6A60-6E23 | disorder |
| P04150 | GCR_HUMAN | ICD-11: 5A11 | mellitus |
| P04150 | GCR_HUMAN | ICD-11: 5B55-5B5F | deficiency |
| P04150 | GCR_HUMAN | ICD-11: 9B71 | Retinopathy |
| P04150 | GCR_HUMAN | ICD-11: 6B00-6B0Z | disorder |
| P37231 | PPARG_HUMAN | ICD-11: BB01 | hypertension |
| P37231 | PPARG_HUMAN | ICD-11: 4A43 | syndrome |
| P37231 | PPARG_HUMAN | ICD-11: 5A11 | mellitus |
| P37231 | PPARG_HUMAN | ICD-11: 5A2Y | complication |
| P37231 | PPARG_HUMAN | ICD-11: 8A20 | disease |
| P37231 | PPARG_HUMAN | ICD-11: 5B80-5B81 | Obesity |
| P37231 | PPARG_HUMAN | ICD-11: 5A11 | mellitus |
| P37231 | PPARG_HUMAN | ICD-11: 5A10 | mellitus |
| P37231 | PPARG_HUMAN | ICD-11: 9C61 | Glaucoma |
| P37231 | PPARG_HUMAN | ICD-11: 5C52 | error |
| P37231 | PPARG_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P37231 | PPARG_HUMAN | ICD-11: FA25 | Gout |
| P37231 | PPARG_HUMAN | ICD-11: DD72 | colitis |
| P37231 | PPARG_HUMAN | ICD-11: 8A40 | sclerosis |
| P37231 | PPARG_HUMAN | ICD-11: 6C4A | disorder |
| P37231 | PPARG_HUMAN | ICD-11: DB92 | disease |
| P37231 | PPARG_HUMAN | ICD-11: 6C43 | disorder |
| P37231 | PPARG_HUMAN | ICD-11: 5C80 | Hyper-lipoproteinaemia |
| P37231 | PPARG_HUMAN | ICD-11: CB03 | pneumonitis |
| P37231 | PPARG_HUMAN | ICD-11: 5C50-5D2Z | disorder |
| P10276 | RARA_HUMAN | ICD-11: 8A20 | disease |
| P10276 | RARA_HUMAN | ICD-11: 2A90 | lymphoma |
| P10276 | RARA_HUMAN | ICD-11: 2A60 | leukaemia |
| P10276 | RARA_HUMAN | ICD-11: 2A37 | syndrome |
| P10276 | RARA_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P10276 | RARA_HUMAN | ICD-11: 1C60-1C62 | disease |
| P10276 | RARA_HUMAN | ICD-11: 2B91 | cancer |
| P13631 | RARG_HUMAN | ICD-11: ED80 | vulgaris |
| P13631 | RARG_HUMAN | ICD-11: 2A60 | leukaemia |
| P13631 | RARG_HUMAN | ICD-11: 2B57 | sarcoma |
| P13631 | RARG_HUMAN | ICD-11: EA90 | Psoriasis |
| P13631 | RARG_HUMAN | ICD-11: CA21 | Emphysema |
| P13631 | RARG_HUMAN | ICD-11: FB31 | calcification/ossification |
| Q03181 | PPARD_HUMAN | ICD-11: DB92 | disease |
| Q03181 | PPARD_HUMAN | ICD-11: 5A11 | mellitus |
| Q03181 | PPARD_HUMAN | ICD-11: DB96 | disease |
| Q03181 | PPARD_HUMAN | ICD-11: 5C80 | Hyper-lipoproteinaemia |
| Q03181 | PPARD_HUMAN | ICD-11: 5B80-5B81 | Obesity |
| Q03181 | PPARD_HUMAN | ICD-11: 8A20 | disease |
| Q03181 | PPARD_HUMAN | ICD-11: 5C80-5C81 | Dyslipidemia |
| Q03181 | PPARD_HUMAN | ICD-11: 5C50-5D2Z | disorder |
| Q03181 | PPARD_HUMAN | ICD-11: 5A10 | mellitus |
| Q03181 | PPARD_HUMAN | ICD-11: 8A04-8D87 | disease |
| Q13133 | NR1H3_HUMAN | ICD-11: 6A70-6A7Z | Depression |
| P14867 | GBRA1_HUMAN | ICD-11: CB00 | syndrome |
| P14867 | GBRA1_HUMAN | ICD-11: 6B00-6B0Z | disorder |
| P14867 | GBRA1_HUMAN | ICD-11: 7A00 | insomnia |
| P14867 | GBRA1_HUMAN | ICD-11: MG30 | pain |
| P14867 | GBRA1_HUMAN | ICD-11: 9A76-9A78 | disease |
| P14867 | GBRA1_HUMAN | ICD-11: GC00 | Cystitis |
| P14867 | GBRA1_HUMAN | ICD-11: 6A70-6A7Z | Depression |
| P14867 | GBRA1_HUMAN | ICD-11: 8A61-8A6Z | Epilepsy/seizure |
| P14867 | GBRA1_HUMAN | ICD-11: 8A80-8A84 | Headache |
| P14867 | GBRA1_HUMAN | ICD-11: 7A00-7A0Z | Insomnia |
| P14867 | GBRA1_HUMAN | ICD-11: DB98 | disorder |
| P14867 | GBRA1_HUMAN | ICD-11: 1F40-1F45 | Malaria |
| P14867 | GBRA1_HUMAN | ICD-11: 6E20-6E8Z | disorder |
| P14867 | GBRA1_HUMAN | ICD-11: 8A66 | epilepticus |
| P14867 | GBRA1_HUMAN | ICD-11: MB47 | abnormality |
| P14867 | GBRA1_HUMAN | ICD-11: 8A04 | disorder |
| P14867 | GBRA1_HUMAN | ICD-11: DD72 | colitis |
| P14867 | GBRA1_HUMAN | ICD-11: GA34 | pain |
| P14867 | GBRA1_HUMAN | ICD-11: 1A00-CA43 | inflammation |
| P55055 | NR1H2_HUMAN | ICD-11: EA80 | eczema |
| P55055 | NR1H2_HUMAN | ICD-11: 6A70-6A7Z | Depression |
| P19793 | RXRA_HUMAN | ICD-11: 2B57 | sarcoma |
| P19793 | RXRA_HUMAN | ICD-11: 2B01 | fungoides |
| P28702 | RXRB_HUMAN | ICD-11: 2B57 | sarcoma |
| P48443 | RXRG_HUMAN | ICD-11: 2B57 | sarcoma |
| P48443 | RXRG_HUMAN | ICD-11: 1F61-1G2Z | Kinetoplastids |
| P48443 | RXRG_HUMAN | ICD-11: 9D45 | impairment |
| P48443 | RXRG_HUMAN | ICD-11: 5A2Y | complication |
| P48443 | RXRG_HUMAN | ICD-11: 2C60-2C6Y | cancer |
| P48443 | RXRG_HUMAN | ICD-11: 2C25 | cancer |
| P48443 | RXRG_HUMAN | ICD-11: 2C10 | cancer |
| P48443 | RXRG_HUMAN | ICD-11: 2C82 | cancer |
| P48443 | RXRG_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P16473 | TSHR_HUMAN | ICD-11: 5A00 | Hypo-thyroidism |
| P16473 | TSHR_HUMAN | ICD-11: 2D10 | cancer |
| P10145 | IL8_HUMAN | ICD-11: MG30-MG3Z | Pain |
| P10145 | IL8_HUMAN | ICD-11: 1D6Y | COVID-19 |
| P10145 | IL8_HUMAN | ICD-11: 2C30 | Melanoma |
| P10145 | IL8_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P10145 | IL8_HUMAN | ICD-11: 5A10 | mellitus |
| P51449 | RORG_HUMAN | ICD-11: 4A40-4A45 | disease |
| P51449 | RORG_HUMAN | ICD-11: 2C25 | cancer |
| P51449 | RORG_HUMAN | ICD-11: EA90 | Psoriasis |
| P51449 | RORG_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| P51449 | RORG_HUMAN | ICD-11: DD70 | disease |
| P51449 | RORG_HUMAN | ICD-11: 8A40 | sclerosis |
| P51449 | RORG_HUMAN | ICD-11: BD40 | disease |
| P51449 | RORG_HUMAN | ICD-11: 2C12 | cancer |
| P51449 | RORG_HUMAN | ICD-11: FA20 | arthritis |
| Q96RI1 | NR1H4_HUMAN | ICD-11: DB96 | disease |
| Q96RI1 | NR1H4_HUMAN | ICD-11: DC11 | Cholelithiasis |
| Q96RI1 | NR1H4_HUMAN | ICD-11: 7A00-7A0Z | Insomnia |
| Q96RI1 | NR1H4_HUMAN | ICD-11: FA00-FA05 | Osteoarthritis |
| Q96RI1 | NR1H4_HUMAN | ICD-11: 2C60-2C6Y | cancer |
| Q96RI1 | NR1H4_HUMAN | ICD-11: DB92 | disease |
| Q96RI1 | NR1H4_HUMAN | ICD-11: GB61 | disease |
| Q96RI1 | NR1H4_HUMAN | ICD-11: LD24 | anomaly |
| Q96RI1 | NR1H4_HUMAN | ICD-11: DB93 | fibrosis/cirrhosis |
| Q96RI1 | NR1H4_HUMAN | ICD-11: 5C80 | Hyper-lipoproteinaemia |
| Q96RI1 | NR1H4_HUMAN | ICD-11: 5A11 | mellitus |
| P10826 | RARB_HUMAN | ICD-11: 2B57 | sarcoma |
| P10826 | RARB_HUMAN | ICD-11: 8A20 | disease |
| P10826 | RARB_HUMAN | ICD-11: 2A90 | lymphoma |
| Q07869 | PPARA_HUMAN | ICD-11: BA00-BE2Z | disease |
| Q07869 | PPARA_HUMAN | ICD-11: 5C80 | Hyperlipidemia |
| Q07869 | PPARA_HUMAN | ICD-11: 5C80 | Hyper-lipoproteinaemia |
| Q07869 | PPARA_HUMAN | ICD-11: 5C52 | error |
| Q07869 | PPARA_HUMAN | ICD-11: 5A11 | mellitus |
| Q07869 | PPARA_HUMAN | ICD-11: 5A10 | mellitus |
| Q07869 | PPARA_HUMAN | ICD-11: DB92 | disease |
| Q07869 | PPARA_HUMAN | ICD-11: 5A2Y | complication |
| Q07869 | PPARA_HUMAN | ICD-11: 5C80-5C81 | Dyslipidemia |
| Q07869 | PPARA_HUMAN | ICD-11: FA25 | Gout |
| Q07869 | PPARA_HUMAN | ICD-11: 2A00-2F9Z | tumour/cancer |
| Q07869 | PPARA_HUMAN | ICD-11: BD10-BD1Z | failure |
| Q07869 | PPARA_HUMAN | ICD-11: BD40 | disease |
| Q07869 | PPARA_HUMAN | ICD-11: CB03 | pneumonitis |
| Q07869 | PPARA_HUMAN | ICD-11: 5C50-5D2Z | disorder |
| Q07869 | PPARA_HUMAN | ICD-11: FA20 | arthritis |
| Q14994 | NR1I3_HUMAN | ICD-11: MB48 | giddiness |