Basic Information

Terpenoid ID TKC053825
Cell line 0
Protein target 5
DiseaseNCIT 0
ORDO 0
ICD 20

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC053825 KB KB (HeLa derivative); HeLa-KB; Strain KB 71.0 % Activity C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC053825 P11473 Vitamin D3 receptor VDR 35481 nM Potency
TKC053825 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 3264 nM Potency
TKC053825 P08684 Cytochrome P450 3A4 CYP3A4 3981 nM Potency
TKC053825 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 62 % Inhibition
TKC053825 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 36 % Inhibition
TKC053825 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 63096 nM Potency
TKC053825 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 12589 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]