Basic Information

Terpenoid ID TKC062636
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC062636 MCF7 598.0 nM IC50 C4194
TKC062636 SF-268 SF-268; SF.268; SF 268 21.0 nM GI50 C60781 Orphanet_94
TKC062636 JY JY-S 12.0 % Inhibition
TKC062636 HepG2 9000.0 nM EC50 C3728 Orphanet_449
TKC062636 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 700.0 nM IC50 C27677
TKC062636 SN12C SN-12C 793.0 nM GI50 C9385 Orphanet_217071
TKC062636 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 1067.0 nM GI50 C3512
TKC062636 UO-31 UO.31; UO31; U031 272.0 nM GI50 C9385 Orphanet_217071
TKC062636 ACHN 592.0 nM GI50 C6975 Orphanet_319298
TKC062636 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 195.0 nM GI50 C2926
TKC062636 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 262.0 nM GI50 C9154 Orphanet_519
TKC062636 SF-539 SF-539; SF-539 BT; SF.539; SF 539 83.0 nM GI50 C3796 Orphanet_251576
TKC062636 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 82.0 nM GI50 C3510
TKC062636 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 68.0 nM GI50 C3224
TKC062636 K562 K562; K.562; K 562; KO; GM05372; GM05372E 287.0 nM GI50 C9110 Orphanet_521
TKC062636 A498 A498 51.0 nM GI50 C9385 Orphanet_217071
TKC062636 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 201.0 nM GI50 C105555
TKC062636 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 953.0 nM GI50 C9142 Orphanet_99861
TKC062636 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 198.0 nM GI50 C3512
TKC062636 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 92.0 nM GI50 C60781 Orphanet_94
TKC062636 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 1040.0 nM GI50 C105555
TKC062636 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 650.0 nM GI50 C105555
TKC062636 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 34.0 nM GI50 C4917 Orphanet_70573
TKC062636 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 249.0 nM GI50 C60781 Orphanet_94
TKC062636 TK-10 TK.10; TK 10; TK10 239.0 nM GI50 C4033 Orphanet_319276
TKC062636 SR SR-786; SR786 118.0 nM GI50 C37193 Orphanet_300895
TKC062636 SW-620 SW-620; SW 620; SW.620 91.0 nM GI50 C4349
TKC062636 M19-MEL M-19; M19 391.0 nM GI50 C3802
TKC062636 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 128.0 nM GI50 C3512
TKC062636 KM12 KM-12; KM.12 624.0 nM GI50 C4910
TKC062636 XF498 XF-498; XF498 23.0 nM GI50 C3058 Orphanet_360
TKC062636 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 76.0 nM GI50 C3802
TKC062636 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 3606.0 nM GI50 C2923
TKC062636 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 23.0 nM GI50 C3242 Orphanet_29073
TKC062636 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 363.0 nM GI50 C105555
TKC062636 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 56.0 nM GI50 C3802
TKC062636 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 54.0 nM GI50 C3224
TKC062636 A549 177.0 nM GI50 C3512
TKC062636 KM-20L2 KM-20L2; KM 20L2; KM 2012 163.0 nM GI50 C4349
TKC062636 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 590.0 nM GI50 C3058 Orphanet_360
TKC062636 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 246.0 nM GI50 C4349
TKC062636 HCT-15 HCT-15; HCT.15; HCT15 114.0 nM GI50 C4349
TKC062636 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 112.0 nM GI50 C4910
TKC062636 EKVX 375.0 nM GI50 C3512
TKC062636 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 73.0 nM GI50 C2926
TKC062636 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 199.0 nM GI50 C4917 Orphanet_70573
TKC062636 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 281.0 nM GI50 C7978
TKC062636 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 44.0 nM GI50 C3224
TKC062636 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 116.0 nM GI50 C3224
TKC062636 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 376.0 nM GI50 C7979 Orphanet_454723
TKC062636 SF-295 SF-295; SF.295; SF 295 344.0 nM GI50 C3058 Orphanet_360
TKC062636 RXF 631 RXF-631L; RXF631L; RXF 631; RXF-631; RXF631 206.0 nM GI50 C9385 Orphanet_217071
TKC062636 SNB-78 SNB78; Surgical Neurology Branch-78 87.0 nM GI50 C3058 Orphanet_360
TKC062636 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 97.0 nM GI50 C3224
TKC062636 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 100.0 nM GI50 C9385 Orphanet_217071
TKC062636 DLD-1 DLD 1; DLD1; CoCL3 86.0 nM GI50 C4349
TKC062636 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 69.0 nM GI50 C7953 Orphanet_99861
TKC062636 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 277.0 nM GI50 C45662 Orphanet_50251
TKC062636 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 1220.0 nM IC50 C3510
TKC062636 HT-29 HT 29; HT29 120.0 nM IC50 C4349
TKC062636 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 96.0 nM GI50 C9385 Orphanet_217071
TKC062636 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 181.0 nM GI50 C4349
TKC062636 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 75.0 nM GI50 C4450

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC062636 P20701 Integrin alpha-L ITGAL 1360 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P20701 ITAL_HUMAN Conjunctiva disorder [ICD-11: 9A60]
P20701 ITAL_HUMAN Psoriasis [ICD-11: EA90]
P20701 ITAL_HUMAN Transplant rejection [ICD-11: NE84]
P20701 ITAL_HUMAN Visual system disease [ICD-11: 9E1Z]
P20701 ITAL_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
P20701 ITAL_HUMAN Diabetes mellitus [ICD-11: 5A10]