Basic Information

Terpenoid ID TKC087533
Chirality TKC030885
Cell line 0
Protein target 26
DiseaseNCIT 0
ORDO 0
ICD 68

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC087533 HepG2 11220.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC087533 P10636 Microtubule-associated protein tau MAPT 3162 nM Potency
TKC087533 P11473 Vitamin D3 receptor VDR 56234 nM Potency
TKC087533 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1458 nM Potency
TKC087533 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 20596 nM Potency
TKC087533 P84022 Mothers against decapentaplegic homolog 3 SMAD3 7080 nM Potency
TKC087533 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 5012 nM Potency
TKC087533 Q06710 Paired box protein Pax-8 PAX8 4030 nM AC50
TKC087533 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 3162 nM Potency
TKC087533 Q99700 Ataxin-2 ATXN2 10000 nM Potency
TKC087533 Q962Y6 Thioredoxin glutathione reductase TGR 5623 nM Potency
TKC087533 Q9UNA4 DNA polymerase iota POLI 14125 nM Potency
TKC087533 O75496 Geminin GMNN 731 nM Potency
TKC087533 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 17783 nM Potency
TKC087533 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 3162 nM Potency
TKC087533 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 355 nM Potency
TKC087533 P07550 Beta-2 adrenergic receptor ADRB2 631 nM Potency
TKC087533 P83916 Chromobox protein homolog 1 CBX1 100000 nM Potency
TKC087533 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 31623 nM Potency
TKC087533 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 29081 nM Potency
TKC087533 Q9Y253 DNA polymerase eta POLH 25119 nM Potency
TKC087533 Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F 3144 nM Potency
TKC087533 P51450 Nuclear receptor ROR-gamma Rorc 7080 nM Potency
TKC087533 P42858 Huntingtin HTT 5623 nM Potency
TKC087533 O15118 NPC intracellular cholesterol transporter 1 NPC1 3981 nM Potency
TKC087533 O75030 Microphthalmia-associated transcription factor MITF 6407 nM AC50
TKC087533 P51151 Ras-related protein Rab-9A RAB9A 3162 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P07550 ADRB2_HUMAN Glaucoma [ICD-11: 9C61]
P07550 ADRB2_HUMAN Asthma [ICD-11: CA23]
P07550 ADRB2_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P07550 ADRB2_HUMAN Conduction disorder [ICD-11: BC63]
P07550 ADRB2_HUMAN Melanoma [ICD-11: 2C30]
P07550 ADRB2_HUMAN Preterm labour/delivery [ICD-11: JB00]
P07550 ADRB2_HUMAN Sleep-related breathing disorder [ICD-11: 7A4Z]
P07550 ADRB2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P07550 ADRB2_HUMAN Stomach cancer [ICD-11: 2B72]
P07550 ADRB2_HUMAN Hypertension [ICD-11: BA00-BA04]
P07550 ADRB2_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P07550 ADRB2_HUMAN Cachexia [ICD-11: MG20]
P07550 ADRB2_HUMAN Dermal/subcutaneous connective tissue atrophy/degeneration [ICD-11: EE40]
P07550 ADRB2_HUMAN Skin and skin-structure infection [ICD-11: 1F28-1G0Z]
P07550 ADRB2_HUMAN Bladder disorder [ICD-11: GC01]
P07550 ADRB2_HUMAN Obesity [ICD-11: 5B80-5B81]
P07550 ADRB2_HUMAN Ejaculatory dysfunction [ICD-11: HA03]
P07550 ADRB2_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]