Basic Information

Terpenoid ID TKC073873
Cell line 0
Protein target 19
DiseaseNCIT 0
ORDO 0
ICD 52

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC073873 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 10770.0 nM CC50
TKC073873 H4 H-4 887.0 nM EC50 C60781 Orphanet_94
TKC073873 HepG2 25119.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC073873 P10636 Microtubule-associated protein tau MAPT 28184 nM Potency
TKC073873 P11473 Vitamin D3 receptor VDR 89125 nM Potency
TKC073873 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1300 nM Potency
TKC073873 P43220 Glucagon-like peptide 1 receptor GLP1R 28184 nM Potency
TKC073873 P84022 Mothers against decapentaplegic homolog 3 SMAD3 15849 nM Potency
TKC073873 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 100000 nM Potency
TKC073873 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 3162 nM Potency
TKC073873 Q99700 Ataxin-2 ATXN2 7943 nM Potency
TKC073873 O75496 Geminin GMNN 6513 nM Potency
TKC073873 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 7080 nM Potency
TKC073873 P83916 Chromobox protein homolog 1 CBX1 89125 nM Potency
TKC073873 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 29081 nM Potency
TKC073873 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 15849 nM Potency
TKC073873 P51450 Nuclear receptor ROR-gamma Rorc 35481 nM Potency
TKC073873 P42858 Huntingtin HTT 5623 nM Potency
TKC073873 O15118 NPC intracellular cholesterol transporter 1 NPC1 6310 nM Potency
TKC073873 O75030 Microphthalmia-associated transcription factor MITF 10269 nM AC50
TKC073873 P51151 Ras-related protein Rab-9A RAB9A 5623 nM Potency
TKC073873 Q194T2 Non-structural protein 1 NS1 1000 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]