Basic Information

Terpenoid ID TKC118929
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC118929 HT-29 HT 29; HT29 15500.0 nM IC50 C4349
TKC118929 C6 C-6; C 6; RGC-6; RGC6; RGc6 40000.0 nM IC50 C64069

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC118929 P51449 Nuclear receptor ROR-gamma RORC 10 nM Ki
TKC118929 P35398 Nuclear receptor ROR-alpha RORA 12 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P51449 RORG_HUMAN Autoimmune disease [ICD-11: 4A40-4A45]
P51449 RORG_HUMAN Lung cancer [ICD-11: 2C25]
P51449 RORG_HUMAN Psoriasis [ICD-11: EA90]
P51449 RORG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51449 RORG_HUMAN Crohn disease [ICD-11: DD70]
P51449 RORG_HUMAN Multiple sclerosis [ICD-11: 8A40]
P51449 RORG_HUMAN Arterial occlusive disease [ICD-11: BD40]
P51449 RORG_HUMAN Liver cancer [ICD-11: 2C12]
P51449 RORG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35398 RORA_HUMAN Liver cancer [ICD-11: 2C12]
P35398 RORA_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]