TKC118419
|
O00329 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
None |
4 |
nM |
IC50 |
TKC118419
|
O00329 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
None |
9 |
nM |
IC50 |
TKC118419
|
O00329 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
None |
9 |
nM |
IC50 |
TKC118419
|
O00329 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
None |
5.5 |
nM |
Kd |
TKC118419
|
O14757 |
Serine/threonine-protein kinase Chk1 |
None |
87 |
% |
Activity |
TKC011761
|
O15530 |
3-phosphoinositide-dependent protein kinase 1 |
None |
46 |
% |
Inhibition |
TKC118419
|
O15530 |
3-phosphoinositide-dependent protein kinase 1 |
None |
91 |
% |
Activity |
TKC007127
|
P00533 |
Epidermal growth factor receptor |
None |
19 |
% |
Inhibition |
TKC025462
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025466
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025475
|
P00533 |
Epidermal growth factor receptor |
None |
197 |
ug.mL-1 |
IC50 |
TKC071640
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC076041
|
P00533 |
Epidermal growth factor receptor |
None |
75 |
% |
Inhibition |
TKC077689
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC106319
|
P00533 |
Epidermal growth factor receptor |
None |
56 |
nM |
IC50 |
TKC108557
|
P00533 |
Epidermal growth factor receptor |
None |
0.82 |
nM |
Kd |
TKC151761
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC200866
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC025462
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025466
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025475
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
125 |
ug.mL-1 |
IC50 |
TKC026211
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
6 |
ug.mL-1 |
IC50 |
TKC026214
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
8 |
ug.mL-1 |
IC50 |
TKC026217
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
4 |
ug.mL-1 |
IC50 |
TKC026229
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
8 |
ug.mL-1 |
IC50 |
TKC012929
|
P05771 |
Protein kinase C beta type |
None |
2 |
nM |
Ki |
TKC055602
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC075924
|
P05771 |
Protein kinase C beta type |
None |
90 |
% |
Inhibition |
TKC090435
|
P05771 |
Protein kinase C beta type |
None |
0.2 |
nM |
Kd |
TKC103074
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC104128
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC104703
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC105956
|
P05771 |
Protein kinase C beta type |
None |
2 |
nM |
Ki |
TKC123088
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC151276
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.8 |
nM |
Ki |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC152742
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC000192
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>19000 |
nM |
IC50 |
TKC005454
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
41400 |
nM |
IC50 |
TKC031060
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
10000 |
nM |
IC50 |
TKC045915
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>30000 |
nM |
IC50 |
TKC045916
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>27000 |
nM |
IC50 |
TKC077689
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
1000 |
nM |
IC50 |
TKC096804
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
1200 |
nM |
IC50 |
TKC105683
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
9000 |
nM |
IC50 |
TKC106945
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>16000 |
nM |
IC50 |
TKC156704
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>16000 |
nM |
IC50 |
TKC191566
|
P08575 |
Receptor-type tyrosine-protein phosphatase C |
None |
>19000 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
170 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
260 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
440 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
440 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
1191 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
450 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
600 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
420 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
10100 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
4800 |
nM |
Kd |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
2110 |
nM |
IC50 |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
558 |
nM |
Ki |
TKC035272
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
320 |
nM |
Ki |
TKC134945
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
1460 |
nM |
Ki |
TKC151761
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
>10000 |
nM |
GI50 |
TKC200866
|
P10415 |
Apoptosis regulator Bcl-2 |
None |
>10000 |
nM |
GI50 |
TKC014892
|
P11387 |
DNA topoisomerase 1 |
None |
3 |
ug.mL-1 |
MIC |
TKC014893
|
P11387 |
DNA topoisomerase 1 |
None |
13 |
ug.mL-1 |
MIC |
TKC017201
|
P11387 |
DNA topoisomerase 1 |
None |
13 |
ug.mL-1 |
MIC |
TKC048122
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048308
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048324
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048330
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048341
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC049414
|
P11387 |
DNA topoisomerase 1 |
None |
25000 |
nM |
IC50 |
TKC049417
|
P11387 |
DNA topoisomerase 1 |
None |
55000 |
nM |
IC50 |
TKC056419
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056423
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056425
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056427
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056430
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058891
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC058895
|
P11387 |
DNA topoisomerase 1 |
None |
48600 |
nM |
IC50 |
TKC058897
|
P11387 |
DNA topoisomerase 1 |
None |
45100 |
nM |
IC50 |
TKC058919
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058921
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058935
|
P11387 |
DNA topoisomerase 1 |
None |
109300 |
nM |
IC50 |
TKC058949
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC058950
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058953
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC058979
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059000
|
P11387 |
DNA topoisomerase 1 |
None |
53700 |
nM |
IC50 |
TKC059030
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059045
|
P11387 |
DNA topoisomerase 1 |
None |
131700 |
nM |
IC50 |
TKC059148
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059149
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059160
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059165
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059317
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC059337
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059344
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059345
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059425
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC072969
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC072970
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC096715
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC100727
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC103324
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC105545
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC137826
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC137841
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC138033
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC138054
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143022
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143033
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143055
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC143114
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC143115
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC145932
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC146257
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC147779
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC147805
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC148618
|
P11387 |
DNA topoisomerase 1 |
None |
106000 |
nM |
IC50 |
TKC205544
|
P11387 |
DNA topoisomerase 1 |
None |
30000 |
nM |
IC50 |
TKC205878
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC207002
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
687 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
280 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
398.1 |
nM |
Ki |
TKC206544
|
P14416 |
D(2) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC006896
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
7700 |
nM |
IC50 |
TKC014575
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
4680 |
nM |
IC50 |
TKC024473
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
10000 |
nM |
IC50 |
TKC024474
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
11000 |
nM |
IC50 |
TKC104241
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
0 |
nM |
EC50 |
TKC118419
|
P24941 |
Cyclin-dependent kinase 2 |
None |
95 |
% |
Activity |
TKC206292
|
P24941 |
Cyclin-dependent kinase 2 |
None |
4800 |
nM |
Kd |
TKC011761
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
54 |
% |
Inhibition |
TKC016414
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
36 |
% |
Activity |
TKC024886
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
48400 |
nM |
IC50 |
TKC025690
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC044763
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
100 |
% |
Inhibition |
TKC115259
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115261
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115272
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC118419
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
96 |
% |
Inhibition |
TKC152148
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC152157
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC174547
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC206776
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
3 |
uM |
Activity |
TKC205544
|
P35462 |
D(3) dopamine receptor |
None |
2489 |
nM |
Ki |
TKC205544
|
P35462 |
D(3) dopamine receptor |
None |
3981.07 |
nM |
Ki |
TKC206544
|
P35462 |
D(3) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC022945
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
4645 |
nM |
Potency |
TKC032619
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
2931 |
nM |
Potency |
TKC035272
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
2612 |
nM |
Potency |
TKC035984
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
4 |
nM |
Potency |
TKC084630
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
3690 |
nM |
Potency |
TKC087988
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
4645 |
nM |
Potency |
TKC092297
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
13092 |
nM |
Potency |
TKC118419
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
40 |
nM |
IC50 |
TKC118419
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
9200 |
nM |
Kd |
TKC205544
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
14689 |
nM |
Potency |
TKC206622
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
23281 |
nM |
Potency |
TKC206688
|
P42345 |
Serine/threonine-protein kinase mTOR |
None |
16482 |
nM |
Potency |
TKC108557
|
P43405 |
Tyrosine-protein kinase SYK |
None |
0.2 |
nM |
IC50 |
TKC112367
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
300 |
nM |
IC50 |
TKC112399
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
2400 |
nM |
IC50 |
TKC117085
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
17300 |
nM |
IC50 |
TKC118351
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
400 |
nM |
IC50 |
TKC118354
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
2000 |
nM |
IC50 |
TKC118356
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
300 |
nM |
IC50 |
TKC118360
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
700 |
nM |
IC50 |
TKC206738
|
P46531 |
Neurogenic locus notch homolog protein 1 |
None |
800 |
nM |
IC50 |
TKC025058
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
1000 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
5 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
19 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
55 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
55000 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
89 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
5 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
15 |
nM |
Kd |
TKC027726
|
P52732 |
Kinesin-like protein KIF11 |
None |
3500 |
nM |
IC50 |
TKC035272
|
P52732 |
Kinesin-like protein KIF11 |
None |
10800 |
nM |
IC50 |
TKC035272
|
P52732 |
Kinesin-like protein KIF11 |
None |
25000 |
nM |
IC50 |
TKC108557
|
P52732 |
Kinesin-like protein KIF11 |
None |
0.3 |
nM |
IC50 |
TKC001786
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
23778 |
nM |
Potency |
TKC005454
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC011384
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
18888 |
nM |
Potency |
TKC014568
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC016277
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
29935 |
nM |
Potency |
TKC018288
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
13371 |
nM |
Potency |
TKC020967
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
2180 |
nM |
IC50 |
TKC020987
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
23778 |
nM |
Potency |
TKC024886
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
21700 |
nM |
IC50 |
TKC025690
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC037521
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
18888 |
nM |
Potency |
TKC040032
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
29935 |
nM |
Potency |
TKC055219
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
13371 |
nM |
Potency |
TKC055869
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
33588 |
nM |
Potency |
TKC066096
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
2119 |
nM |
Potency |
TKC066411
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
2994 |
nM |
Potency |
TKC077689
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC082378
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
15003 |
nM |
Potency |
TKC087988
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC088678
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
37686 |
nM |
Potency |
TKC091895
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC098704
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC101726
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC104088
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
33588 |
nM |
Potency |
TKC107557
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC112826
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
33588 |
nM |
Potency |
TKC115259
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC115261
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC115272
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
100000 |
nM |
IC50 |
TKC118419
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
6 |
nM |
IC50 |
TKC118419
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
1500 |
nM |
Ki |
TKC118419
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
24 |
nM |
IC50 |
TKC141147
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
13371 |
nM |
Potency |
TKC150277
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
23778 |
nM |
Potency |
TKC151609
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
23778 |
nM |
Potency |
TKC151885
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
6702 |
nM |
Potency |
TKC151902
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
26680 |
nM |
Potency |
TKC151910
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
18888 |
nM |
Potency |
TKC152148
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC152157
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC159332
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
21192 |
nM |
Potency |
TKC171689
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
23778 |
nM |
Potency |
TKC174547
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
>100000 |
nM |
IC50 |
TKC206362
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
13371 |
nM |
Potency |
TKC206589
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
29935 |
nM |
Potency |
TKC206760
|
P53350 |
Serine/threonine-protein kinase PLK1 |
None |
21192 |
nM |
Potency |
TKC021620
|
P60568 |
Interleukin-2 |
None |
3 |
nM |
Kd |
TKC116180
|
P60568 |
Interleukin-2 |
None |
0 |
nM |
Kd |
TKC005454
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1360 |
nM |
IC50 |
TKC005475
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7340 |
nM |
IC50 |
TKC010010
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>20000 |
nM |
IC50 |
TKC011921
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1995 |
nM |
Potency |
TKC012261
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
280 |
nM |
IC50 |
TKC012262
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3180 |
nM |
IC50 |
TKC012971
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC014568
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
8510 |
nM |
IC50 |
TKC017189
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10600 |
nM |
IC50 |
TKC017192
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1700 |
nM |
IC50 |
TKC017193
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2300 |
nM |
IC50 |
TKC020116
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
501 |
nM |
Potency |
TKC022945
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2512 |
nM |
Potency |
TKC023570
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15800 |
nM |
IC50 |
TKC030239
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
Potency |
TKC035272
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10000 |
nM |
Potency |
TKC037547
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10 |
% |
Activity |
TKC038977
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
820 |
nM |
IC50 |
TKC045710
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
500 |
nM |
IC50 |
TKC045931
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2900 |
nM |
IC50 |
TKC045946
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2900 |
nM |
IC50 |
TKC047694
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
IC50 |
TKC047695
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
68 |
nM |
IC50 |
TKC056482
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>100000 |
nM |
IC50 |
TKC056482
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>100000 |
nM |
IC50 |
TKC062172
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15000 |
nM |
IC50 |
TKC062175
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062182
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062192
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062193
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC065782
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC081893
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
400 |
nM |
IC50 |
TKC092297
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
39811 |
nM |
Potency |
TKC094057
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC094058
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>20000 |
nM |
IC50 |
TKC095493
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3162 |
nM |
Potency |
TKC096011
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1 |
nM |
Potency |
TKC096012
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
251 |
nM |
Potency |
TKC100416
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC100643
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC100990
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
159 |
nM |
Potency |
TKC101618
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15849 |
nM |
Potency |
TKC102145
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1259 |
nM |
Potency |
TKC102589
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
8000 |
nM |
EC50 |
TKC103149
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
31623 |
nM |
Potency |
TKC103159
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
270 |
nM |
IC50 |
TKC103433
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC103494
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79 |
nM |
Potency |
TKC103496
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20 |
nM |
Potency |
TKC104070
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
40 |
nM |
Potency |
TKC104071
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
100 |
nM |
Potency |
TKC104114
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
126 |
nM |
Potency |
TKC104664
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
794 |
nM |
Potency |
TKC105037
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
794 |
nM |
Potency |
TKC105510
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
6000 |
nM |
EC50 |
TKC105710
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC106426
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC106576
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
13000 |
nM |
EC50 |
TKC107086
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
19953 |
nM |
Potency |
TKC109561
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
251 |
nM |
Potency |
TKC110002
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
Potency |
TKC110007
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7943 |
nM |
Potency |
TKC111738
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
16 |
nM |
Potency |
TKC112789
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC112906
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
5012 |
nM |
Potency |
TKC114819
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC117993
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2000 |
nM |
EC50 |
TKC117997
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
40 |
nM |
EC50 |
TKC118004
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2512 |
nM |
Potency |
TKC118012
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
600 |
nM |
EC50 |
TKC118131
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
126 |
nM |
Potency |
TKC134897
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3400 |
nM |
IC50 |
TKC137120
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
IC50 |
TKC137126
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2400 |
nM |
IC50 |
TKC137243
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
IC50 |
TKC144475
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25000 |
nM |
IC50 |
TKC151571
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7943 |
nM |
Potency |
TKC205806
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
5012 |
nM |
Potency |
TKC206042
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
6310 |
nM |
Potency |
TKC206395
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC206453
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC206617
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12700 |
nM |
IC50 |
TKC206688
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
Potency |
TKC206726
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79 |
nM |
Potency |
TKC206760
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
50119 |
nM |
Potency |
TKC206780
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3981 |
nM |
Potency |
TKC206812
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79433 |
nM |
Potency |
TKC206816
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC206872
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC206889
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
501 |
nM |
Potency |
TKC206890
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20 |
nM |
EC50 |
TKC206901
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
159 |
nM |
Potency |
TKC076129
|
Q16790 |
Carbonic anhydrase 9 |
None |
980 |
nM |
Ki |
TKC020117
|
Q92769 |
Histone deacetylase 2 |
None |
15 |
nM |
Ki |
TKC118419
|
Q9BUB5 |
MAP kinase-interacting serine/threonine-protein kinase 1 |
None |
81 |
% |
Activity |
TKC118419
|
Q9HBH9 |
MAP kinase-interacting serine/threonine-protein kinase 2 |
None |
97 |
% |
Activity |
TKC011761
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
18 |
% |
Inhibition |
TKC024886
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
2190 |
nM |
IC50 |
TKC025690
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
3380 |
nM |
IC50 |
TKC115259
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
9330 |
nM |
IC50 |
TKC115261
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
4160 |
nM |
IC50 |
TKC115272
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
>100000 |
nM |
IC50 |
TKC115273
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
4360 |
nM |
IC50 |
TKC152148
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
7550 |
nM |
IC50 |
TKC152157
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
4730 |
nM |
IC50 |
TKC174547
|
Q9UM73 |
ALK tyrosine kinase receptor |
None |
>100000 |
nM |
IC50 |