Basic Information

Terpenoid ID TKC206589
Chirality TKC150277
Cell line 0
Protein target 8
DiseaseNCIT 0
ORDO 0
ICD 16

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206589 HepG2 35481.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206589 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 50119 nM Potency
TKC206589 P53350 Serine/threonine-protein kinase PLK1 PLK1 29935 nM Potency
TKC206589 P84022 Mothers against decapentaplegic homolog 3 SMAD3 25119 nM Potency
TKC206589 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 89125 nM Potency
TKC206589 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 14575 nM Potency
TKC206589 P63096 Guanine nucleotide-binding protein G GNAI1 50119 nM Potency
TKC206589 Q8WZA2 Rap guanine nucleotide exchange factor 4 RAPGEF4 44668 nM Potency
TKC206589 P62826 GTP-binding nuclear protein Ran RAN 1032 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P53350 PLK1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P53350 PLK1_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P53350 PLK1_HUMAN Prostate cancer [ICD-11: 2C82]
P53350 PLK1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P53350 PLK1_HUMAN Pancreatic cancer [ICD-11: 2C10]
P53350 PLK1_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P53350 PLK1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]