Basic Information

Terpenoid ID TKC206622
Chirality TKC012929
Cell line 0
Protein target 16
DiseaseNCIT 0
ORDO 0
ICD 49

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206622 HEK293 6510.0 nM Potency
TKC206622 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 5300.0 nM CC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206622 Q99700 Ataxin-2 ATXN2 2239 nM Potency
TKC206622 Q9UBT6 DNA polymerase kappa POLK 26680 nM Potency
TKC206622 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 5973 nM Potency
TKC206622 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 35481 nM Potency
TKC206622 O42275 Acetylcholinesterase ache 13 % Inhibition
TKC206622 P21728 D(1A) dopamine receptor DRD1 231 nM Potency
TKC206622 P81908 Cholinesterase BCHE -1 % Inhibition
TKC206622 P83916 Chromobox protein homolog 1 CBX1 1192 nM Potency
TKC206622 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 7943 nM Potency
TKC206622 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 4 nM Potency
TKC206622 P49798 Regulator of G-protein signaling 4 RGS4 15003 nM Potency
TKC206622 P11021 Endoplasmic reticulum chaperone BiP HSPA5 36898 nM Potency
TKC206622 O15118 NPC intracellular cholesterol transporter 1 NPC1 58048 nM Potency
TKC206622 P51151 Ras-related protein Rab-9A RAB9A 63096 nM Potency
TKC206622 P42345 Serine/threonine-protein kinase mTOR MTOR 23281 nM Potency
TKC206622 O15648 ATP-dependent 6-phosphofructokinase pfk 757 nM Potency
TKC206622 O00167 Eyes absent homolog 2 EYA2 100000 nM Potency
TKC206622 P06869 Urokinase-type plasminogen activator Plau 93 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P21728 DRD1_HUMAN Abortion [ICD-11: JA00]
P21728 DRD1_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P21728 DRD1_HUMAN Hypertension [ICD-11: BA00-BA04]
P21728 DRD1_HUMAN Parkinsonism [ICD-11: 8A00]
P21728 DRD1_HUMAN Cocaine use disorder [ICD-11: 6C45]
P21728 DRD1_HUMAN Schizophrenia [ICD-11: 6A20]
P21728 DRD1_HUMAN Tic disorder [ICD-11: 8A05]
P21728 DRD1_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P21728 DRD1_HUMAN Psychotic disorder [ICD-11: 6A20-6A25]
P21728 DRD1_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P21728 DRD1_HUMAN Pain [ICD-11: MG30-MG3Z]
P21728 DRD1_HUMAN Glaucoma [ICD-11: 9C61]
P21728 DRD1_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
P21728 DRD1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P21728 DRD1_HUMAN Unspecific substance use disorder [ICD-11: 6C4Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11021 BIP_HUMAN Melanoma [ICD-11: 2C30]
P11021 BIP_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]
P42345 MTOR_HUMAN Arteries/arterioles disorder [ICD-11: BD52]
P42345 MTOR_HUMAN Chronic myelomonocytic leukaemia [ICD-11: 2A40]
P42345 MTOR_HUMAN Hydrocephalus [ICD-11: 8D64]
P42345 MTOR_HUMAN Multiple myeloma [ICD-11: 2A83]
P42345 MTOR_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P42345 MTOR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P42345 MTOR_HUMAN Transplant rejection [ICD-11: NE84]
P42345 MTOR_HUMAN Sarcoma [ICD-11: 2A60-2C35]
P42345 MTOR_HUMAN Bladder cancer [ICD-11: 2C94]
P42345 MTOR_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P42345 MTOR_HUMAN Endometrial cancer [ICD-11: 2C76]
P42345 MTOR_HUMAN Head and neck cancer [ICD-11: 2D42]
P42345 MTOR_HUMAN Liver cancer [ICD-11: 2C12]
P42345 MTOR_HUMAN Lung cancer [ICD-11: 2C25]
P42345 MTOR_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P42345 MTOR_HUMAN Malignant mesenchymal neoplasm [ICD-11: 2B5D-2B5Y]
P42345 MTOR_HUMAN Metastatic lymph node neoplasm [ICD-11: 2D60]
P42345 MTOR_HUMAN Pain [ICD-11: MG30-MG3Z]
P42345 MTOR_HUMAN Pancreatic cancer [ICD-11: 2C10]
P42345 MTOR_HUMAN Prostate cancer [ICD-11: 2C82]
P42345 MTOR_HUMAN Pulmonary hypertension [ICD-11: BB01]
P42345 MTOR_HUMAN Lymphangioleiomyomatosis [ICD-11: CB07]
P42345 MTOR_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P42345 MTOR_HUMAN Pleural mesothelioma [ICD-11: 2C26]
P42345 MTOR_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P42345 MTOR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P42345 MTOR_HUMAN Ulcerative colitis [ICD-11: DD71]