Basic Information

Name [ICD-11: DB61-GB90]
Protein Number 14
Molecule Number 210

Active subnetwork

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC055903 P00734 Prothrombin None 4 nM IC50
TKC055903 P00734 Prothrombin None 50 nM IC50
TKC064786 P00734 Prothrombin None 130 nM IC50
TKC064787 P00734 Prothrombin None 70 nM IC50
TKC101989 P00734 Prothrombin None 4000 nM IC50
TKC106074 P00734 Prothrombin None >50000 nM IC50
TKC106074 P00734 Prothrombin None >50000 nM IC50
TKC122980 P00734 Prothrombin None 9200 nM IC50
TKC139119 P00734 Prothrombin None 90 nM IC50
TKC141433 P00734 Prothrombin None 18 nM IC50
TKC005744 P00742 Coagulation factor X None 27900 nM IC50
TKC012492 P00742 Coagulation factor X None 13385 nM Ki
TKC013400 P00742 Coagulation factor X None 2500 nM IC50
TKC013430 P00742 Coagulation factor X None 11418 nM IC50
TKC055903 P00742 Coagulation factor X None >20000 nM IC50
TKC107140 P00742 Coagulation factor X None 7991 nM Ki
TKC124270 P00742 Coagulation factor X None 27558 nM Ki
TKC128698 P00742 Coagulation factor X None 7200 nM IC50
TKC128699 P00742 Coagulation factor X None 7165 nM IC50
TKC205733 P00742 Coagulation factor X None 1023 nM IC50
TKC073833 P00749 Urokinase-type plasminogen activator None 58479 nM Potency
TKC076529 P00749 Urokinase-type plasminogen activator None 23281 nM Potency
TKC082279 P00749 Urokinase-type plasminogen activator None 52119 nM Potency
TKC008187 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30200 nM IC50
TKC023515 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 53 % Inhibition
TKC025574 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 52 % Inhibition
TKC026893 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21 % Inhibition
TKC026895 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 61 % Inhibition
TKC057019 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 22300 nM IC50
TKC100777 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30 % Inhibition
TKC101031 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1500 nM IC50
TKC101538 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 39 % Inhibition
TKC101847 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1000 nM IC50
TKC103703 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 40 % Inhibition
TKC137314 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 8400 nM IC50
TKC138471 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21700 nM IC50
TKC020117 P09917 Polyunsaturated fatty acid 5-lipoxygenase None -67 % Inhibition
TKC024485 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >50000 nM IC50
TKC024587 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 600 nM IC50
TKC024956 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 18000 nM IC50
TKC024992 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 450 nM IC50
TKC024993 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 14000 nM IC50
TKC025965 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >150000 nM IC50
TKC026303 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 4600 nM IC50
TKC026309 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 680 nM IC50
TKC027255 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >67 % Activity
TKC034201 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >200000 nM IC50
TKC040026 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 72 % Inhibition
TKC051154 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 2700 nM IC50
TKC056482 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >64 % Activity
TKC058811 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 42000 nM IC50
TKC058812 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >93 % Activity
TKC064374 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 42000 nM IC50
TKC064407 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >72 % Activity
TKC065375 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >70 % Activity
TKC071640 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >60 % Activity
TKC076350 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 100 % Activity
TKC077689 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 100 % Activity
TKC077703 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >86 % Activity
TKC078194 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 31800 nM IC50
TKC082039 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 48 % Inhibition
TKC088678 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 24800 nM IC50
TKC089448 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 35 % Inhibition
TKC094647 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 97 % Activity
TKC107943 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 2000 nM IC50
TKC123028 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 30400 nM IC50
TKC124303 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 750 nM IC50
TKC133309 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >200000 nM IC50
TKC133656 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 25100 nM IC50
TKC134278 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >200000 nM IC50
TKC139322 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >67 % Activity
TKC139366 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 3000 nM IC50
TKC141401 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 42000 nM IC50
TKC141499 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 25700 nM IC50
TKC141805 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >53 % Activity
TKC142849 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >70 % Activity
TKC142897 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 30600 nM IC50
TKC142922 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >61 % Activity
TKC143539 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 100 % Activity
TKC145848 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 42000 nM IC50
TKC145932 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >56 % Activity
TKC145968 P09917 Polyunsaturated fatty acid 5-lipoxygenase None 100 % Activity
TKC146774 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >63 % Activity
TKC149759 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >73 % Activity
TKC150706 P09917 Polyunsaturated fatty acid 5-lipoxygenase None >62 % Activity
TKC001669 P10275 Androgen receptor None 260 nM IC50
TKC006934 P10275 Androgen receptor None 50119 nM Potency
TKC013304 P10275 Androgen receptor None 70795 nM Potency
TKC019571 P10275 Androgen receptor None 19953 nM Potency
TKC021325 P10275 Androgen receptor None 31623 nM Potency
TKC021332 P10275 Androgen receptor None 31623 nM Potency
TKC023246 P10275 Androgen receptor None 449 nM IC50
TKC030239 P10275 Androgen receptor None 14 nM Potency
TKC035272 P10275 Androgen receptor None 15849 nM Potency
TKC056140 P10275 Androgen receptor None 50 % Activity
TKC066169 P10275 Androgen receptor None 3981 nM Potency
TKC074867 P10275 Androgen receptor None 28184 nM Potency
TKC075769 P10275 Androgen receptor None 355 nM Potency
TKC079001 P10275 Androgen receptor None 1 nM Potency
TKC096012 P10275 Androgen receptor None 178 nM Potency
TKC100644 P10275 Androgen receptor None 35481 nM Potency
TKC102407 P10275 Androgen receptor None 44668 nM Potency
TKC106878 P10275 Androgen receptor None 238 nM IC50
TKC107086 P10275 Androgen receptor None 17783 nM Potency
TKC107735 P10275 Androgen receptor None 3981 nM Potency
TKC111738 P10275 Androgen receptor None 17783 nM Potency
TKC112923 P10275 Androgen receptor None 212 nM IC50
TKC114095 P10275 Androgen receptor None 1790 nM IC50
TKC114511 P10275 Androgen receptor None 315 nM Ki
TKC115268 P10275 Androgen receptor None 35481 nM Potency
TKC115284 P10275 Androgen receptor None 1 nM Ki
TKC117154 P10275 Androgen receptor None 580 nM IC50
TKC120161 P10275 Androgen receptor None 44668 nM Potency
TKC122884 P10275 Androgen receptor None 39811 nM Potency
TKC122892 P10275 Androgen receptor None 10000 nM IC50
TKC134780 P10275 Androgen receptor None 2 nM Potency
TKC147240 P10275 Androgen receptor None 50 % Activity
TKC206652 P10275 Androgen receptor None 50 nM Potency
TKC206688 P10275 Androgen receptor None 224 nM Potency
TKC206690 P10275 Androgen receptor None 36 nM Potency
TKC206759 P10275 Androgen receptor None 2 nM Potency
TKC206759 P10275 Androgen receptor None 3.9 nM IC50
TKC206759 P10275 Androgen receptor None 4.7 nM IC50
TKC206759 P10275 Androgen receptor None 4.2 nM IC50
TKC206759 P10275 Androgen receptor None 29 nM Ki
TKC206759 P10275 Androgen receptor None 1.1 nM EC50
TKC206759 P10275 Androgen receptor None 2.7 nM IC50
TKC206759 P10275 Androgen receptor None 2.7 nM IC50
TKC206759 P10275 Androgen receptor None 2.7 nM IC50
TKC206759 P10275 Androgen receptor None 30 nM IC50
TKC206759 P10275 Androgen receptor None 4.57 nM IC50
TKC206770 P10275 Androgen receptor None 224 nM Potency
TKC206779 P10275 Androgen receptor None 2 nM Potency
TKC206812 P10275 Androgen receptor None 220 nM IC50
TKC206816 P10275 Androgen receptor None 9 nM Ki
TKC206816 P10275 Androgen receptor None 8.5 nM Ki
TKC206816 P10275 Androgen receptor None 8.5 nM Ki
TKC206816 P10275 Androgen receptor None 8.5 nM Ki
TKC206816 P10275 Androgen receptor None 8.5 nM Ki
TKC206816 P10275 Androgen receptor None 37 nM IC50
TKC206816 P10275 Androgen receptor None 8.5 nM Ki
TKC206816 P10275 Androgen receptor None 35 nM Ki
TKC206816 P10275 Androgen receptor None 14 nM IC50
TKC019954 P12821 Angiotensin-converting enzyme None 15 % Inhibition
TKC039868 P12821 Angiotensin-converting enzyme None 17 % Inhibition
TKC013753 P15121 Aldo-keto reductase family 1 member B1 None 1100000 nM Km
TKC035272 P15121 Aldo-keto reductase family 1 member B1 None 500 nM Ki
TKC035273 P15121 Aldo-keto reductase family 1 member B1 None 1500 nM Ki
TKC048308 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC048325 P15121 Aldo-keto reductase family 1 member B1 None 147300 nM IC50
TKC048341 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC049175 P15121 Aldo-keto reductase family 1 member B1 None 25 ug.mL-1 IC50
TKC051021 P15121 Aldo-keto reductase family 1 member B1 None >193500 nM IC50
TKC051028 P15121 Aldo-keto reductase family 1 member B1 None 22800 nM IC50
TKC051029 P15121 Aldo-keto reductase family 1 member B1 None >193500 nM IC50
TKC051032 P15121 Aldo-keto reductase family 1 member B1 None >189400 nM IC50
TKC055115 P15121 Aldo-keto reductase family 1 member B1 None 12000 ug.mL-1 IC50
TKC056482 P15121 Aldo-keto reductase family 1 member B1 None 41000 nM IC50
TKC057931 P15121 Aldo-keto reductase family 1 member B1 None 6 /min Kcat
TKC060859 P15121 Aldo-keto reductase family 1 member B1 None 25 ug.mL-1 IC50
TKC063401 P15121 Aldo-keto reductase family 1 member B1 None 25 ug.mL-1 IC50
TKC063402 P15121 Aldo-keto reductase family 1 member B1 None 25 ug.mL-1 IC50
TKC063751 P15121 Aldo-keto reductase family 1 member B1 None >195300 nM IC50
TKC077689 P15121 Aldo-keto reductase family 1 member B1 None 124000 nM IC50
TKC081137 P15121 Aldo-keto reductase family 1 member B1 None >193500 nM IC50
TKC088678 P15121 Aldo-keto reductase family 1 member B1 None 280000 nM IC50
TKC092322 P15121 Aldo-keto reductase family 1 member B1 None 400000 nM Km
TKC101833 P15121 Aldo-keto reductase family 1 member B1 None >193500 nM IC50
TKC123088 P15121 Aldo-keto reductase family 1 member B1 None 11000 nM IC50
TKC137747 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC137786 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC137982 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC138004 P15121 Aldo-keto reductase family 1 member B1 None >200000 nM IC50
TKC141585 P15121 Aldo-keto reductase family 1 member B1 None >194400 nM IC50
TKC142922 P15121 Aldo-keto reductase family 1 member B1 None 84000 nM IC50
TKC145170 P15121 Aldo-keto reductase family 1 member B1 None >199200 nM IC50
TKC145534 P15121 Aldo-keto reductase family 1 member B1 None >187900 nM IC50
TKC145540 P15121 Aldo-keto reductase family 1 member B1 None >174200 nM IC50
TKC145547 P15121 Aldo-keto reductase family 1 member B1 None >174700 nM IC50
TKC146774 P15121 Aldo-keto reductase family 1 member B1 None 72000 nM IC50
TKC150706 P15121 Aldo-keto reductase family 1 member B1 None 34000 nM IC50
TKC151691 P15121 Aldo-keto reductase family 1 member B1 None 119200 nM IC50
TKC151763 P15121 Aldo-keto reductase family 1 member B1 None 43800 nM IC50
TKC151921 P15121 Aldo-keto reductase family 1 member B1 None >194400 nM IC50
TKC156642 P15121 Aldo-keto reductase family 1 member B1 None >189400 nM IC50
TKC206760 P15121 Aldo-keto reductase family 1 member B1 None 6900 nM IC50
TKC207025 P15121 Aldo-keto reductase family 1 member B1 None >183900 nM IC50
TKC031476 P17787 Neuronal acetylcholine receptor subunit beta-2 None 62500 nM IC50
TKC031535 P17787 Neuronal acetylcholine receptor subunit beta-2 None 970 nM IC50
TKC031538 P17787 Neuronal acetylcholine receptor subunit beta-2 None 1570 nM IC50
TKC007073 P25105 Platelet-activating factor receptor None 5 uM Binding affinity
TKC105026 P25105 Platelet-activating factor receptor None 575 nM IC50
TKC105028 P25105 Platelet-activating factor receptor None 575 nM IC50
TKC106540 P25105 Platelet-activating factor receptor None 964 nM Ki
TKC147486 P25105 Platelet-activating factor receptor None 4 uM Binding affinity
TKC147612 P25105 Platelet-activating factor receptor None 5 uM Binding affinity
TKC151784 P25105 Platelet-activating factor receptor None 128 nM IC50
TKC205457 P25105 Platelet-activating factor receptor None 1259 nM IC50
TKC082111 P25116 Proteinase-activated receptor 1 None 20000 nM IC50
TKC031476 P36544 Neuronal acetylcholine receptor subunit alpha-7 None 100000 nM IC50
TKC031535 P36544 Neuronal acetylcholine receptor subunit alpha-7 None 13800 nM IC50
TKC031538 P36544 Neuronal acetylcholine receptor subunit alpha-7 None 4640 nM IC50
TKC036511 P36544 Neuronal acetylcholine receptor subunit alpha-7 None 100000 nM IC50
TKC135961 P36544 Neuronal acetylcholine receptor subunit alpha-7 None 3100 nM IC50
TKC118419 P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform None 8 nM Kd
TKC118419 P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform None 7.6 nM Kd
TKC118419 P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform None 10 nM IC50
TKC118419 P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform None 15 nM IC50
TKC118419 P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform None 14 nM IC50
TKC108557 P43405 Tyrosine-protein kinase SYK None 0.2 nM IC50