Basic Information

Terpenoid ID TKC025574
Chirality TKC101538
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 13

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC025574 HepG2 48.0 % Inhibition C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC025574 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 52 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P04035 HMDH_HUMAN Blood/blood-forming organ sympton [ICD-11: MA14]
P04035 HMDH_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P04035 HMDH_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
P04035 HMDH_HUMAN Hepatitis virus infection [ICD-11: 1E50-1E51]
P04035 HMDH_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P04035 HMDH_HUMAN Multiple myeloma [ICD-11: 2A83]
P04035 HMDH_HUMAN Multiple sclerosis [ICD-11: 8A40]
P04035 HMDH_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P04035 HMDH_HUMAN Pain [ICD-11: MG30-MG3Z]
P04035 HMDH_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P04035 HMDH_HUMAN Arterial occlusive disease [ICD-11: BD40]
P04035 HMDH_HUMAN Coronary atherosclerosis [ICD-11: BA80]
P04035 HMDH_HUMAN Thrombosis [ICD-11: DB61-GB90]