Basic Information

Terpenoid ID TKC035273
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 10

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC035273 MCF7 4.0 ug.mL-1 IC50 C4194
TKC035273 HT-29 HT 29; HT29 3.0 ug.mL-1 IC50 C4349
TKC035273 SN12C SN-12C 2735.0 nM GI50 C9385 Orphanet_217071
TKC035273 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 3614.0 nM GI50 C3512
TKC035273 UO-31 UO.31; UO31; U031 3304.0 nM GI50 C9385 Orphanet_217071
TKC035273 ACHN 2427.0 nM GI50 C6975 Orphanet_319298
TKC035273 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 4457.0 nM GI50 C9154 Orphanet_519
TKC035273 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 2198.0 nM GI50 C2926
TKC035273 SF-539 SF-539; SF-539 BT; SF.539; SF 539 4355.0 nM GI50 C3796 Orphanet_251576
TKC035273 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 5754.0 nM GI50 C3224
TKC035273 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 9226.0 nM GI50 C3510
TKC035273 K562 K562; K.562; K 562; KO; GM05372; GM05372E 11776.0 nM GI50 C9110 Orphanet_521
TKC035273 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 3365.0 nM GI50 C105555
TKC035273 A498 A498 11403.0 nM GI50 C9385 Orphanet_217071
TKC035273 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 7534.0 nM GI50 C9142 Orphanet_99861
TKC035273 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 2979.0 nM GI50 C3512
TKC035273 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 3199.0 nM GI50 C60781 Orphanet_94
TKC035273 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 7079.0 nM GI50 C105555
TKC035273 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 3741.0 nM GI50 C105555
TKC035273 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 3882.0 nM GI50 C60781 Orphanet_94
TKC035273 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 5105.0 nM GI50 C4917 Orphanet_70573
TKC035273 SR SR-786; SR786 4395.0 nM GI50 C37193 Orphanet_300895
TKC035273 TK-10 TK.10; TK 10; TK10 6714.0 nM GI50 C4033 Orphanet_319276
TKC035273 SW-620 SW-620; SW 620; SW.620 5333.0 nM GI50 C4349
TKC035273 M19-MEL M-19; M19 3648.0 nM GI50 C3802
TKC035273 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 2624.0 nM GI50 C3512
TKC035273 XF498 XF-498; XF498 3733.0 nM GI50 C3058 Orphanet_360
TKC035273 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 9863.0 nM GI50 C3802
TKC035273 KM12 KM-12; KM.12 5047.0 nM GI50 C4910
TKC035273 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 4315.0 nM GI50 C3242 Orphanet_29073
TKC035273 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 5321.0 nM GI50 C2923
TKC035273 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 3864.0 nM GI50 C105555
TKC035273 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 4446.0 nM GI50 C3224
TKC035273 A549 3524.0 nM GI50 C3512
TKC035273 KM-20L2 KM-20L2; KM 20L2; KM 2012 6012.0 nM GI50 C4349
TKC035273 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 2655.0 nM GI50 C4349
TKC035273 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 2404.0 nM GI50 C3058 Orphanet_360
TKC035273 HCT-15 HCT-15; HCT.15; HCT15 3741.0 nM GI50 C4349
TKC035273 SF-268 SF-268; SF.268; SF 268 5715.0 nM GI50 C60781 Orphanet_94
TKC035273 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 2606.0 nM GI50 C4910
TKC035273 EKVX 4864.0 nM GI50 C3512
TKC035273 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 3963.0 nM GI50 C2926
TKC035273 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 3076.0 nM GI50 C4917 Orphanet_70573
TKC035273 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 4188.0 nM GI50 C7978
TKC035273 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 4721.0 nM GI50 C4450
TKC035273 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 11912.0 nM GI50 C3224
TKC035273 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 6081.0 nM GI50 C3224
TKC035273 SF-295 SF-295; SF.295; SF 295 4188.0 nM GI50 C3058 Orphanet_360
TKC035273 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 5470.0 nM GI50 C7979 Orphanet_454723
TKC035273 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 10914.0 nM GI50 C3224
TKC035273 SNB-78 SNB78; Surgical Neurology Branch-78 25293.0 nM GI50 C3058 Orphanet_360
TKC035273 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 5164.0 nM GI50 C7953 Orphanet_99861
TKC035273 DLD-1 DLD 1; DLD1; CoCL3 4375.0 nM GI50 C4349
TKC035273 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 2427.0 nM GI50 C45662 Orphanet_50251
TKC035273 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 6607.0 nM GI50 C3510
TKC035273 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 2523.0 nM GI50 C9385 Orphanet_217071
TKC035273 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 1888.0 nM GI50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC035273 P15121 Aldo-keto reductase family 1 member B1 AKR1B1 1500 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P15121 ALDR_HUMAN Neuropathy [ICD-11: 8C0Z]
P15121 ALDR_HUMAN Pain [ICD-11: MG30-MG3Z]
P15121 ALDR_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P15121 ALDR_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P15121 ALDR_HUMAN Thrombosis [ICD-11: DB61-GB90]
P15121 ALDR_HUMAN Cataract [ICD-11: 9B10]
P15121 ALDR_HUMAN Glaucoma [ICD-11: 9C61]
P15121 ALDR_HUMAN Schizophrenia [ICD-11: 6A20]
P15121 ALDR_HUMAN Gout [ICD-11: FA25]
P15121 ALDR_HUMAN Head and neck cancer [ICD-11: 2D42]