Uniport ID | P08684 |
Organism | Homo sapiens |
Protein | Cytochrome P450 3A4 |
Gene | CYP3A4 |
Molecule Number | 197 |
ID | Uniport | Pref Name | Value | Unit | Type |
---|---|---|---|---|---|
TKC000602 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC003636 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC003637 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC004452 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC004454 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC004758 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC025230 | P08684 | Cytochrome P450 3A4 | >10000 | nM | IC50 |
TKC025231 | P08684 | Cytochrome P450 3A4 | >10000 | nM | IC50 |
TKC030239 | P08684 | Cytochrome P450 3A4 | >19953 | nM | Potency |
TKC030239 | P08684 | Cytochrome P450 3A4 | >50000 | nM | IC50 |
TKC075769 | P08684 | Cytochrome P450 3A4 | >50000 | nM | IC50 |
TKC112653 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC112655 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC122980 | P08684 | Cytochrome P450 3A4 | >100000 | nM | IC50 |
TKC146761 | P08684 | Cytochrome P450 3A4 | 125000.0 | nM | IC50 |
TKC032983 | P08684 | Cytochrome P450 3A4 | 98200.0 | nM | IC50 |
TKC077034 | P08684 | Cytochrome P450 3A4 | 62500.0 | nM | IC50 |
TKC097717 | P08684 | Cytochrome P450 3A4 | 48400.0 | nM | IC50 |
TKC037686 | P08684 | Cytochrome P450 3A4 | 42600.0 | nM | IC50 |
TKC008359 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC013304 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC096012 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC098345 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC101920 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC102204 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC102439 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC104404 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC104602 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC105168 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC106240 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC132834 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC135961 | P08684 | Cytochrome P450 3A4 | 39811.0 | nM | Potency |
TKC134571 | P08684 | Cytochrome P450 3A4 | 35500.0 | nM | IC50 |
TKC035272 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | AC50 |
TKC045513 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC057133 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC078496 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC087991 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC090094 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC103257 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC104767 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC105530 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC105784 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC106198 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC106301 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC107201 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC115268 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC117710 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC151675 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC151875 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC206114 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC206386 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC206760 | P08684 | Cytochrome P450 3A4 | 31623.0 | nM | Potency |
TKC012971 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | AC50 |
TKC031954 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC032619 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC040026 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC079001 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC092348 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC101020 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC103736 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC105034 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC107818 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC108109 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC108732 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC111349 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC138780 | P08684 | Cytochrome P450 3A4 | 25119.0 | nM | Potency |
TKC151523 | P08684 | Cytochrome P450 3A4 | 23200.0 | nM | Ki |
TKC077038 | P08684 | Cytochrome P450 3A4 | 21800.0 | nM | IC50 |
TKC034979 | P08684 | Cytochrome P450 3A4 | 20000.0 | nM | Ki |
TKC103023 | P08684 | Cytochrome P450 3A4 | 19953.0 | nM | Potency |
TKC103041 | P08684 | Cytochrome P450 3A4 | 19953.0 | nM | Potency |
TKC207209 | P08684 | Cytochrome P450 3A4 | 19953.0 | nM | Potency |
TKC005454 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC016418 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC068076 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC074866 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC087664 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC088678 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC092297 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC101907 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC107332 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC107830 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC108295 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC112745 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC112754 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC118004 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC148601 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC150706 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC206453 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC206754 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC206777 | P08684 | Cytochrome P450 3A4 | 15849.0 | nM | Potency |
TKC013753 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC034640 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC034641 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC039869 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC040829 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC102032 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC102120 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC103799 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC104293 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC104656 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC105033 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC105037 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC105346 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC106426 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC106840 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC112909 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC147290 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC151571 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC206452 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC206783 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | AC50 |
TKC206884 | P08684 | Cytochrome P450 3A4 | 12589.0 | nM | Potency |
TKC011526 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC034078 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC062321 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC101092 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC104091 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC105378 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC107593 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC112906 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC112914 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC113146 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC135244 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC205806 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC206690 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | Potency |
TKC206759 | P08684 | Cytochrome P450 3A4 | 10000.0 | nM | IC50 |
TKC040094 | P08684 | Cytochrome P450 3A4 | 8800.0 | nM | IC50 |
TKC013736 | P08684 | Cytochrome P450 3A4 | 8700.0 | nM | Km |
TKC034083 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | Potency |
TKC066013 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | Potency |
TKC101617 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | AC50 |
TKC104977 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | Potency |
TKC206688 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | Potency |
TKC206901 | P08684 | Cytochrome P450 3A4 | 7943.0 | nM | AC50 |
TKC207071 | P08684 | Cytochrome P450 3A4 | 7500.0 | nM | Km |
TKC062333 | P08684 | Cytochrome P450 3A4 | 6310.0 | nM | Potency |
TKC023263 | P08684 | Cytochrome P450 3A4 | 5070.0 | nM | IC50 |
TKC102407 | P08684 | Cytochrome P450 3A4 | 5012.0 | nM | Potency |
TKC106184 | P08684 | Cytochrome P450 3A4 | 5012.0 | nM | Potency |
TKC107067 | P08684 | Cytochrome P450 3A4 | 5012.0 | nM | Potency |
TKC141032 | P08684 | Cytochrome P450 3A4 | 5012.0 | nM | Potency |
TKC207099 | P08684 | Cytochrome P450 3A4 | 5012.0 | nM | Potency |
TKC011412 | P08684 | Cytochrome P450 3A4 | 4300.0 | nM | Ki |
TKC053825 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC100649 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC102540 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC103149 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | AC50 |
TKC106358 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC114819 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC151522 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC206816 | P08684 | Cytochrome P450 3A4 | 3981.0 | nM | Potency |
TKC107021 | P08684 | Cytochrome P450 3A4 | 3162.0 | nM | Potency |
TKC109561 | P08684 | Cytochrome P450 3A4 | 3162.0 | nM | AC50 |
TKC113150 | P08684 | Cytochrome P450 3A4 | 3162.0 | nM | Potency |
TKC114511 | P08684 | Cytochrome P450 3A4 | 3162.0 | nM | Potency |
TKC207282 | P08684 | Cytochrome P450 3A4 | 3162.0 | nM | AC50 |
TKC011075 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC055066 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC055209 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC101111 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC104435 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC105295 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC105424 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC106212 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | AC50 |
TKC107104 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC107525 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC107944 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC113125 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC138777 | P08684 | Cytochrome P450 3A4 | 2512.0 | nM | Potency |
TKC038725 | P08684 | Cytochrome P450 3A4 | 1995.0 | nM | Potency |
TKC100701 | P08684 | Cytochrome P450 3A4 | 1995.0 | nM | Potency |
TKC106232 | P08684 | Cytochrome P450 3A4 | 1995.0 | nM | AC50 |
TKC111738 | P08684 | Cytochrome P450 3A4 | 1995.0 | nM | Potency |
TKC062327 | P08684 | Cytochrome P450 3A4 | 1585.0 | nM | Potency |
TKC062332 | P08684 | Cytochrome P450 3A4 | 1585.0 | nM | Potency |
TKC095493 | P08684 | Cytochrome P450 3A4 | 1585.0 | nM | AC50 |
TKC113149 | P08684 | Cytochrome P450 3A4 | 1585.0 | nM | Potency |
TKC148482 | P08684 | Cytochrome P450 3A4 | 1585.0 | nM | Potency |
TKC066332 | P08684 | Cytochrome P450 3A4 | 1259.0 | nM | Potency |
TKC104979 | P08684 | Cytochrome P450 3A4 | 1259.0 | nM | Potency |
TKC102743 | P08684 | Cytochrome P450 3A4 | 1000.0 | nM | Potency |
TKC206365 | P08684 | Cytochrome P450 3A4 | 1000.0 | nM | Potency |
TKC206687 | P08684 | Cytochrome P450 3A4 | 1000.0 | nM | Potency |
TKC206812 | P08684 | Cytochrome P450 3A4 | 1000.0 | nM | Potency |
TKC020117 | P08684 | Cytochrome P450 3A4 | 631.0 | nM | Potency |
TKC105153 | P08684 | Cytochrome P450 3A4 | 501.0 | nM | Potency |
TKC100636 | P08684 | Cytochrome P450 3A4 | 398.0 | nM | Potency |
TKC104664 | P08684 | Cytochrome P450 3A4 | 398.0 | nM | Potency |
TKC151758 | P08684 | Cytochrome P450 3A4 | 316.0 | nM | Potency |
TKC205809 | P08684 | Cytochrome P450 3A4 | 66.0 | % | Activity |
TKC110956 | P08684 | Cytochrome P450 3A4 | 26.0 | pmol/min | Drug metabolism |
TKC206689 | P08684 | Cytochrome P450 3A4 | 25.0 | nM | Potency |
TKC039868 | P08684 | Cytochrome P450 3A4 | 10.0 | % | Drug metabolism |
TKC122904 | P08684 | Cytochrome P450 3A4 | 9.0 | pmol/min | Vmax |
TKC101618 | P08684 | Cytochrome P450 3A4 | 6.0 | nM | Potency |
TKC110481 | P08684 | Cytochrome P450 3A4 | 1.0 | uL/mg/min | Vmax/Km |