Basic Information

Terpenoid ID TKC113125
Chirality TKC206777
Cell line 0
Protein target 10
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC113125 P08684 Cytochrome P450 3A4 CYP3A4 2512 nM Potency
TKC113125 P15207 Androgen receptor Ar 20 nM Ki
TKC113125 P28482 Mitogen-activated protein kinase 1 MAPK1 22387 nM Potency
TKC113125 O09028 Gamma-aminobutyric acid receptor subunit pi Gabrp 80 nM Kd
TKC113125 Q9Z0U4 Gamma-aminobutyric acid type B receptor subunit 1 Gabbr1 13 nM IC50
TKC113125 P34897 Serine hydroxymethyltransferase, mitochondrial SHMT2 66 % Inhibition
TKC113125 P19969 Gamma-aminobutyric acid receptor subunit alpha-5 Gabra5 21 nM Ki
TKC113125 P23576 Gamma-aminobutyric acid receptor subunit alpha-2 Gabra2 41 nM Ki
TKC113125 P28471 Gamma-aminobutyric acid receptor subunit alpha-4 Gabra4 1900 nM Ki
TKC113125 P30191 Gamma-aminobutyric acid receptor subunit alpha-6 Gabra6 51 nM Ki
TKC113125 P62813 Gamma-aminobutyric acid receptor subunit alpha-1 Gabra1 17.5 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P28482 MK01_HUMAN Melanoma [ICD-11: 2C30]
P28482 MK01_HUMAN Pancreatic cancer [ICD-11: 2C10]
P28482 MK01_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P28482 MK01_HUMAN Arteries/arterioles disorder [ICD-11: BD52]
P28482 MK01_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P28482 MK01_HUMAN Transplant rejection [ICD-11: NE84]
P28482 MK01_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P28482 MK01_HUMAN Rheumatoid arthritis [ICD-11: FA20]