Basic Information

Terpenoid ID TKC112909
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 28

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112909 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 16360 nM Potency
TKC112909 P08684 Cytochrome P450 3A4 CYP3A4 12589 nM Potency
TKC112909 P06276 Cholinesterase BCHE 102660 nM IC50
TKC112909 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 104 % Inhibition
TKC112909 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 128 % Inhibition
TKC112909 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 125893 nM Potency
TKC112909 P43220 Glucagon-like peptide 1 receptor GLP1R 10000 nM Potency
TKC112909 P11511 Aromatase CYP19A1 43 nM Ki
TKC112909 P11511 Aromatase CYP19A1 120 nM Ki
TKC112909 P11511 Aromatase CYP19A1 320 nM Ki
TKC112909 P83916 Chromobox protein homolog 1 CBX1 56234 nM Potency
TKC112909 O35627 Nuclear receptor subfamily 1 group I member 3 Nr1i3 89 % Remaining activity
TKC112909 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 HSD17B7 21 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P06276 CHLE_HUMAN Pain [ICD-11: MG30-MG3Z]
P06276 CHLE_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P06276 CHLE_HUMAN Alzheimer disease [ICD-11: 8A20]
P06276 CHLE_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P06276 CHLE_HUMAN Eexposure to noxious substances harmful effect [ICD-11: NE61]
P06276 CHLE_HUMAN Toxicity [ICD-11: N.A.]
P06276 CHLE_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P11511 CP19A_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11511 CP19A_HUMAN Cushing syndrome [ICD-11: 5A70]
P11511 CP19A_HUMAN Oesophagitis [ICD-11: DA24]
P11511 CP19A_HUMAN Endometriosis [ICD-11: GA10]
P11511 CP19A_HUMAN Neuropathy [ICD-11: 8C0Z]
P11511 CP19A_HUMAN Bladder cancer [ICD-11: 2C94]
P11511 CP19A_HUMAN Prostate disease [ICD-11: GA91]
P11511 CP19A_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11511 CP19A_HUMAN Cushing syndrome [ICD-11: 5A70]
P11511 CP19A_HUMAN Oesophagitis [ICD-11: DA24]
P11511 CP19A_HUMAN Endometriosis [ICD-11: GA10]
P11511 CP19A_HUMAN Neuropathy [ICD-11: 8C0Z]
P11511 CP19A_HUMAN Bladder cancer [ICD-11: 2C94]
P11511 CP19A_HUMAN Prostate disease [ICD-11: GA91]
P11511 CP19A_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11511 CP19A_HUMAN Cushing syndrome [ICD-11: 5A70]
P11511 CP19A_HUMAN Oesophagitis [ICD-11: DA24]
P11511 CP19A_HUMAN Endometriosis [ICD-11: GA10]
P11511 CP19A_HUMAN Neuropathy [ICD-11: 8C0Z]
P11511 CP19A_HUMAN Bladder cancer [ICD-11: 2C94]
P11511 CP19A_HUMAN Prostate disease [ICD-11: GA91]