Basic Information

Terpenoid ID TKC110481
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC110481 HepG2 1706.0 nM IC50 C3728 Orphanet_449
TKC110481 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 760.0 nM IC50 C27677
TKC110481 BGC-823 BGC823 8500.0 nM IC50 C27677
TKC110481 Bel-7402 Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 100.0 nM IC50 C27677
TKC110481 A549 6500.0 nM IC50 C3512

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC110481 P08684 Cytochrome P450 3A4 CYP3A4 1 uL/mg/min Vmax/Km
TKC110481 O42275 Acetylcholinesterase ache 11 % Inhibition
TKC110481 P81908 Cholinesterase BCHE 4 % Inhibition
TKC110481 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 45 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]