Basic Information

Terpenoid ID TKC112745
Chirality TKC206754
Cell line 0
Protein target 11
DiseaseNCIT 0
ORDO 0
ICD 20

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112745 Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH2 25119 nM Potency
TKC112745 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 6513 nM Potency
TKC112745 P08684 Cytochrome P450 3A4 CYP3A4 15849 nM Potency
TKC112745 Q9UNA4 DNA polymerase iota POLI 5623 nM Potency
TKC112745 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 25119 nM Potency
TKC112745 P28482 Mitogen-activated protein kinase 1 MAPK1 31623 nM Potency
TKC112745 Q01453 Peripheral myelin protein 22 PMP22 95283 nM Potency
TKC112745 O00255 Menin MEN1 17783 nM Potency
TKC112745 P02791 Ferritin light chain FTL 44668 nM Potency
TKC112745 P02545 Prelamin-A/C LMNA 708 nM Potency
TKC112745 Q194T2 Non-structural protein 1 NS1 7080 nM Potency
TKC112745 P37058 Testosterone 17-beta-dehydrogenase 3 HSD17B3 1 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q12809 KCNH2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q12809 KCNH2_HUMAN Sleep-wake disorder [ICD-11: 7A00-7B2Z]
Q12809 KCNH2_HUMAN Malaria [ICD-11: 1F40-1F45]
Q12809 KCNH2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q12809 KCNH2_HUMAN Pain [ICD-11: MG30-MG3Z]
Q12809 KCNH2_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
Q12809 KCNH2_HUMAN Angina pectoris [ICD-11: BA40]
Q12809 KCNH2_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
Q12809 KCNH2_HUMAN Ovarian cancer [ICD-11: 2C73]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P28482 MK01_HUMAN Melanoma [ICD-11: 2C30]
P28482 MK01_HUMAN Pancreatic cancer [ICD-11: 2C10]
P28482 MK01_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P28482 MK01_HUMAN Arteries/arterioles disorder [ICD-11: BD52]
P28482 MK01_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P28482 MK01_HUMAN Transplant rejection [ICD-11: NE84]
P28482 MK01_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P28482 MK01_HUMAN Rheumatoid arthritis [ICD-11: FA20]