Basic Information

Terpenoid ID TKC045513
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 10

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC045513 SN12C SN-12C 100000.0 nM GI50 C9385 Orphanet_217071
TKC045513 ACHN 100000.0 nM GI50 C6975 Orphanet_319298
TKC045513 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 100000.0 nM GI50 C3512
TKC045513 UO-31 UO.31; UO31; U031 100000.0 nM GI50 C9385 Orphanet_217071
TKC045513 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 10000.0 nM GI50 C2926
TKC045513 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 100000.0 nM GI50 C3510
TKC045513 SF-539 SF-539; SF-539 BT; SF.539; SF 539 100000.0 nM GI50 C3796 Orphanet_251576
TKC045513 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 100000.0 nM GI50 C3224
TKC045513 K562 K562; K.562; K 562; KO; GM05372; GM05372E 100000.0 nM GI50 C9110 Orphanet_521
TKC045513 A498 A498 100000.0 nM GI50 C9385 Orphanet_217071
TKC045513 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 100000.0 nM GI50 C105555
TKC045513 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 100000.0 nM GI50 C9142 Orphanet_99861
TKC045513 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 100000.0 nM GI50 C3512
TKC045513 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 100000.0 nM GI50 C60781 Orphanet_94
TKC045513 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 100000.0 nM GI50 C105555
TKC045513 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 100000.0 nM GI50 C105555
TKC045513 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 100000.0 nM GI50 C60781 Orphanet_94
TKC045513 TK-10 TK.10; TK 10; TK10 100000.0 nM GI50 C4033 Orphanet_319276
TKC045513 SW-620 SW-620; SW 620; SW.620 100000.0 nM GI50 C4349
TKC045513 M19-MEL M-19; M19 100000.0 nM GI50 C3802
TKC045513 KM12 KM-12; KM.12 100000.0 nM GI50 C4910
TKC045513 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 100000.0 nM GI50 C3512
TKC045513 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 100000.0 nM GI50 C3802
TKC045513 XF498 XF-498; XF498 100000.0 nM GI50 C3058 Orphanet_360
TKC045513 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 100000.0 nM GI50 C105555
TKC045513 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 100000.0 nM GI50 C3802
TKC045513 KM-20L2 KM-20L2; KM 20L2; KM 2012 100000.0 nM GI50 C4349
TKC045513 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 100000.0 nM GI50 C3224
TKC045513 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 100000.0 nM GI50 C4349
TKC045513 A549 100000.0 nM GI50 C3512
TKC045513 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 100000.0 nM GI50 C3058 Orphanet_360
TKC045513 HCT-15 HCT-15; HCT.15; HCT15 100000.0 nM GI50 C4349
TKC045513 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 100000.0 nM GI50 C4910
TKC045513 EKVX 100000.0 nM GI50 C3512
TKC045513 SF-268 SF-268; SF.268; SF 268 100000.0 nM GI50 C60781 Orphanet_94
TKC045513 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 100000.0 nM GI50 C2926
TKC045513 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 100000.0 nM GI50 C4917 Orphanet_70573
TKC045513 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 100000.0 nM GI50 C7978
TKC045513 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 100000.0 nM GI50 C4450
TKC045513 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 100000.0 nM GI50 C3224
TKC045513 SF-295 SF-295; SF.295; SF 295 100000.0 nM GI50 C3058 Orphanet_360
TKC045513 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 100000.0 nM GI50 C7979 Orphanet_454723
TKC045513 RXF 631 RXF-631L; RXF631L; RXF 631; RXF-631; RXF631 100000.0 nM GI50 C9385 Orphanet_217071
TKC045513 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 10.0 nM GI50 C9385 Orphanet_217071
TKC045513 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 100000.0 nM GI50 C3224
TKC045513 SNB-78 SNB78; Surgical Neurology Branch-78 100000.0 nM GI50 C3058 Orphanet_360
TKC045513 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 100000.0 nM GI50 C7953 Orphanet_99861
TKC045513 DLD-1 DLD 1; DLD1; CoCL3 100000.0 nM GI50 C4349
TKC045513 HT-29 HT 29; HT29 100000.0 nM GI50 C4349
TKC045513 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 100000.0 nM GI50 C45662 Orphanet_50251
TKC045513 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 100000.0 nM GI50 C3510
TKC045513 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 100000.0 nM GI50 C9385 Orphanet_217071
TKC045513 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 100000.0 nM GI50 C4349
TKC045513 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 100000.0 nM GI50 C4450

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC045513 P10636 Microtubule-associated protein tau MAPT 1413 nM Potency
TKC045513 P08684 Cytochrome P450 3A4 CYP3A4 31623 nM Potency
TKC045513 P46063 ATP-dependent DNA helicase Q1 RECQL 39811 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]