Basic Information

Terpenoid ID TKC206783
Chirality TKC113161
Cell line 0
Protein target 13
DiseaseNCIT 0
ORDO 0
ICD 41

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206783 P08684 Cytochrome P450 3A4 CYP3A4 12589 nM AC50
TKC206783 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 39811 nM Potency
TKC206783 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 44668 nM Potency
TKC206783 P84022 Mothers against decapentaplegic homolog 3 SMAD3 35481 nM Potency
TKC206783 O75496 Geminin GMNN 316 nM Potency
TKC206783 P37840 Alpha-synuclein SNCA 35481 nM Potency
TKC206783 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 25119 nM Potency
TKC206783 P08482 Muscarinic acetylcholine receptor M1 Chrm1 17783 nM Potency
TKC206783 Q9Y6A2 Cholesterol 24-hydroxylase CYP46A1 2500 nM Ki
TKC206783 O15399 Glutamate receptor ionotropic, NMDA 2D GRIN2D 78000 nM EC50
TKC206783 Q12879 Glutamate receptor ionotropic, NMDA 2A GRIN2A 21000 nM EC50
TKC206783 Q13224 Glutamate receptor ionotropic, NMDA 2B GRIN2B 33000 nM EC50
TKC206783 Q14957 Glutamate receptor ionotropic, NMDA 2C GRIN2C 83000 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q9Y6A2 CP46A_HUMAN Acidosis [ICD-11: 5C73]
Q9Y6A2 CP46A_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
Q9Y6A2 CP46A_HUMAN Epileptic encephalopathy [ICD-11: 8A62]
Q9Y6A2 CP46A_HUMAN Phakomatoses/hamartoneoplastic syndrome [ICD-11: LD2D]
Q9Y6A2 CP46A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O15399 NMDE4_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q12879 NMDE1_HUMAN Nutritional deficiency [ICD-11: 5B50-5B71]
Q12879 NMDE1_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
Q12879 NMDE1_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
Q12879 NMDE1_HUMAN Alzheimer disease [ICD-11: 8A20]
Q12879 NMDE1_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
Q12879 NMDE1_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q13224 NMDE2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q13224 NMDE2_HUMAN Chronic pain [ICD-11: MG30]
Q13224 NMDE2_HUMAN Cerebral ischaemic stroke [ICD-11: 8B11]
Q13224 NMDE2_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13224 NMDE2_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
Q13224 NMDE2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q13224 NMDE2_HUMAN Neuropathy [ICD-11: 8C0Z]
Q13224 NMDE2_HUMAN Parkinsonism [ICD-11: 8A00]
Q13224 NMDE2_HUMAN Cardiac arrest [ICD-11: MC82]
Q13224 NMDE2_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
Q13224 NMDE2_HUMAN General pain disorder [ICD-11: 8E43]
Q13224 NMDE2_HUMAN Alzheimer disease [ICD-11: 8A20]
Q13224 NMDE2_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
Q13224 NMDE2_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q13224 NMDE2_HUMAN Intracranial injury [ICD-11: NA07]
Q14957 NMDE3_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]