Basic Information

Terpenoid ID TKC034078
Chirality TKC151345
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC034078 SN12C SN-12C 4436.0 nM GI50 C9385 Orphanet_217071
TKC034078 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 13709.0 nM GI50 C3512
TKC034078 ACHN 13964.0 nM GI50 C6975 Orphanet_319298
TKC034078 UO-31 UO.31; UO31; U031 4977.0 nM GI50 C9385 Orphanet_217071
TKC034078 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 4256.0 nM GI50 C2926
TKC034078 SF-539 SF-539; SF-539 BT; SF.539; SF 539 1950.0 nM GI50 C3796 Orphanet_251576
TKC034078 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 7638.0 nM GI50 C3510
TKC034078 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 3524.0 nM GI50 C3224
TKC034078 A498 A498 6887.0 nM GI50 C9385 Orphanet_217071
TKC034078 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 10447.0 nM GI50 C105555
TKC034078 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 20512.0 nM GI50 C3512
TKC034078 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 10116.0 nM GI50 C60781 Orphanet_94
TKC034078 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 11749.0 nM GI50 C105555
TKC034078 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 19454.0 nM GI50 C105555
TKC034078 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 2535.0 nM GI50 C4917 Orphanet_70573
TKC034078 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 11220.0 nM GI50 C60781 Orphanet_94
TKC034078 TK-10 TK.10; TK 10; TK10 11376.0 nM GI50 C4033 Orphanet_319276
TKC034078 SR SR-786; SR786 100000.0 nM GI50 C37193 Orphanet_300895
TKC034078 M19-MEL M-19; M19 4699.0 nM GI50 C3802
TKC034078 SW-620 SW-620; SW 620; SW.620 3917.0 nM GI50 C4349
TKC034078 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 1901.0 nM GI50 C3512
TKC034078 KM12 KM-12; KM.12 2239.0 nM GI50 C4910
TKC034078 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 6339.0 nM GI50 C3802
TKC034078 XF498 XF-498; XF498 3690.0 nM GI50 C3058 Orphanet_360
TKC034078 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 15205.0 nM GI50 C2923
TKC034078 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 13366.0 nM GI50 C105555
TKC034078 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 1216.0 nM GI50 C3802
TKC034078 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 3908.0 nM GI50 C3224
TKC034078 KM-20L2 KM-20L2; KM 20L2; KM 2012 12218.0 nM GI50 C4349
TKC034078 A549 12162.0 nM GI50 C3512
TKC034078 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 7228.0 nM GI50 C3058 Orphanet_360
TKC034078 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 13552.0 nM GI50 C4349
TKC034078 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 4046.0 nM GI50 C4910
TKC034078 HCT-15 HCT-15; HCT.15; HCT15 10864.0 nM GI50 C4349
TKC034078 SF-268 SF-268; SF.268; SF 268 12942.0 nM GI50 C60781 Orphanet_94
TKC034078 EKVX 17100.0 nM GI50 C3512
TKC034078 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 3199.0 nM GI50 C2926
TKC034078 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 16181.0 nM GI50 C4917 Orphanet_70573
TKC034078 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 19454.0 nM GI50 C7978
TKC034078 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 5559.0 nM GI50 C3224
TKC034078 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 4677.0 nM GI50 C4450
TKC034078 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 6622.0 nM GI50 C3224
TKC034078 SF-295 SF-295; SF.295; SF 295 11403.0 nM GI50 C3058 Orphanet_360
TKC034078 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 19011.0 nM GI50 C7979 Orphanet_454723
TKC034078 RXF 631 RXF-631L; RXF631L; RXF 631; RXF-631; RXF631 4236.0 nM GI50 C9385 Orphanet_217071
TKC034078 SNB-78 SNB78; Surgical Neurology Branch-78 3266.0 nM GI50 C3058 Orphanet_360
TKC034078 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 10304.0 nM GI50 C3224
TKC034078 DLD-1 DLD 1; DLD1; CoCL3 3491.0 nM GI50 C4349
TKC034078 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 100000.0 nM GI50 C7953 Orphanet_99861
TKC034078 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 12912.0 nM GI50 C45662 Orphanet_50251
TKC034078 HT-29 HT 29; HT29 7145.0 nM GI50 C4349
TKC034078 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 11695.0 nM GI50 C3510
TKC034078 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 2931.0 nM GI50 C4349
TKC034078 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 2767.0 nM GI50 C9385 Orphanet_217071
TKC034078 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 17498.0 nM GI50 C4450

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC034078 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 15849 nM Potency
TKC034078 P08684 Cytochrome P450 3A4 CYP3A4 10000 nM Potency
TKC034078 P51450 Nuclear receptor ROR-gamma Rorc 35481 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]