Basic Information

Terpenoid ID TKC206386
Chirality TKC115268
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206386 P00352 Retinal dehydrogenase 1 ALDH1A1 39811 nM Potency
TKC206386 P10636 Microtubule-associated protein tau MAPT 31623 nM Potency
TKC206386 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 23715 nM Potency
TKC206386 P08684 Cytochrome P450 3A4 CYP3A4 31623 nM Potency
TKC206386 Q9UBT6 DNA polymerase kappa POLK 11220 nM Potency
TKC206386 O00255 Menin MEN1 39811 nM Potency
TKC206386 P25779 Cruzipain 15849 nM Potency
TKC206386 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 15849 nM Potency
TKC206386 P51450 Nuclear receptor ROR-gamma Rorc 7080 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]