TKC206051
|
P07858 |
Cathepsin B |
None |
103500 |
nM |
IC50 |
TKC022234
|
P08246 |
Neutrophil elastase |
None |
>1 |
% |
Inhibition |
TKC022237
|
P08246 |
Neutrophil elastase |
None |
100000 |
nM |
IC50 |
TKC022245
|
P08246 |
Neutrophil elastase |
None |
18000 |
nM |
IC50 |
TKC055903
|
P08246 |
Neutrophil elastase |
None |
>10000 |
nM |
IC50 |
TKC056482
|
P08246 |
Neutrophil elastase |
None |
416 |
nM |
IC50 |
TKC093449
|
P08246 |
Neutrophil elastase |
None |
100000 |
nM |
IC50 |
TKC093451
|
P08246 |
Neutrophil elastase |
None |
>40 |
% |
Inhibition |
TKC104777
|
P08246 |
Neutrophil elastase |
None |
1560 |
nM |
IC50 |
TKC009193
|
P08253 |
72 kDa type IV collagenase |
None |
33260 |
nM |
IC50 |
TKC020117
|
P08253 |
72 kDa type IV collagenase |
None |
90 |
% |
Inhibition |
TKC023429
|
P08253 |
72 kDa type IV collagenase |
None |
0 |
ug.mL-1 |
IC50 |
TKC087988
|
P49327 |
Fatty acid synthase |
None |
>40 |
% |
Inhibition |
TKC113582
|
P50281 |
Matrix metalloproteinase-14 |
None |
19 |
ug.mL-1 |
IC50 |
TKC016794
|
P55085 |
Proteinase-activated receptor 2 |
None |
14 |
nM |
IC50 |
TKC055291
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC055602
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
3110 |
nM |
EC50 |
TKC056482
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1430 |
nM |
EC50 |
TKC064374
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077533
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077595
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077599
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077601
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077608
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
120 |
nM |
EC50 |
TKC077609
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077612
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077626
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC077689
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2250 |
nM |
EC50 |
TKC082589
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082597
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082600
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
5000 |
nM |
EC50 |
TKC082608
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082609
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082639
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082652
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC082703
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
3650 |
nM |
EC50 |
TKC082710
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
7730 |
nM |
EC50 |
TKC082711
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
7880 |
nM |
EC50 |
TKC082712
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
3170 |
nM |
EC50 |
TKC103074
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC104925
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2080 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6100 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6710 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
30000 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6710 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6700 |
nM |
EC50 |
TKC106240
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
10290 |
nM |
EC50 |
TKC106250
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2390 |
nM |
EC50 |
TKC106250
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
36400 |
nM |
EC50 |
TKC108191
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1750 |
nM |
EC50 |
TKC109617
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
4890 |
nM |
EC50 |
TKC109618
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
36700 |
nM |
EC50 |
TKC109619
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2390 |
nM |
EC50 |
TKC109619
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
36400 |
nM |
EC50 |
TKC109621
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
33900 |
nM |
EC50 |
TKC109622
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
30000 |
nM |
EC50 |
TKC109625
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1180 |
nM |
EC50 |
TKC112754
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
3330 |
nM |
EC50 |
TKC112784
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1250 |
nM |
EC50 |
TKC112785
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
540 |
nM |
EC50 |
TKC112787
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
290 |
nM |
EC50 |
TKC112788
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
47800 |
nM |
EC50 |
TKC118553
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6080 |
nM |
EC50 |
TKC123088
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1040 |
nM |
EC50 |
TKC141147
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
4710 |
nM |
EC50 |
TKC141164
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC141622
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC145848
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC145932
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC150706
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>7 |
% |
Efficacy |
TKC152742
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC152765
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC152829
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC166596
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC170602
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC170603
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
>0 |
% |
Efficacy |
TKC206669
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
31600 |
nM |
EC50 |
TKC206670
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
3880 |
nM |
EC50 |
TKC206671
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
1920 |
nM |
EC50 |
TKC206672
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
4390 |
nM |
EC50 |
TKC206754
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2620 |
nM |
EC50 |
TKC206758
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6220 |
nM |
EC50 |
TKC206759
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
18300 |
nM |
EC50 |
TKC206760
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
680 |
nM |
EC50 |
TKC206760
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
580 |
nM |
EC50 |
TKC206760
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
5600 |
nM |
EC50 |
TKC206760
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
5000 |
nM |
EC50 |
TKC206760
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
730 |
nM |
EC50 |
TKC206761
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
590 |
nM |
EC50 |
TKC206765
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
7010 |
nM |
EC50 |
TKC206813
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
850 |
nM |
EC50 |
TKC206814
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
290 |
nM |
EC50 |
TKC206816
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
2770 |
nM |
EC50 |
TKC206849
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
4950 |
nM |
EC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
6000 |
nM |
IC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
13600 |
nM |
EC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
13600 |
nM |
EC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
13600 |
nM |
EC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
13600 |
nM |
EC50 |
TKC206884
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
19830 |
nM |
EC50 |
TKC206885
|
Q8TDU6 |
G-protein coupled bile acid receptor 1 |
None |
160000 |
nM |
EC50 |
TKC021583
|
Q965D5 |
Enoyl-acyl-carrier protein reductase |
None |
100 |
ug.mL-1 |
IC50 |
TKC105316
|
Q965D5 |
Enoyl-acyl-carrier protein reductase |
None |
20 |
ug.mL-1 |
IC50 |
TKC116761
|
Q965D5 |
Enoyl-acyl-carrier protein reductase |
None |
18 |
ug.mL-1 |
IC50 |
TKC013753
|
Q96RI1 |
Bile acid receptor |
None |
16 |
nM |
Potency |
TKC016414
|
Q96RI1 |
Bile acid receptor |
None |
9700 |
nM |
IC50 |
TKC016817
|
Q96RI1 |
Bile acid receptor |
None |
3900 |
nM |
IC50 |
TKC017639
|
Q96RI1 |
Bile acid receptor |
None |
1 |
% |
Activity |
TKC019374
|
Q96RI1 |
Bile acid receptor |
None |
4 |
nM |
Potency |
TKC021321
|
Q96RI1 |
Bile acid receptor |
None |
39811 |
nM |
Potency |
TKC021365
|
Q96RI1 |
Bile acid receptor |
None |
28184 |
nM |
Potency |
TKC021425
|
Q96RI1 |
Bile acid receptor |
None |
28184 |
nM |
Potency |
TKC022931
|
Q96RI1 |
Bile acid receptor |
None |
50119 |
nM |
Potency |
TKC026455
|
Q96RI1 |
Bile acid receptor |
None |
17000 |
nM |
IC50 |
TKC027095
|
Q96RI1 |
Bile acid receptor |
None |
1500 |
nM |
IC50 |
TKC027096
|
Q96RI1 |
Bile acid receptor |
None |
1500 |
nM |
IC50 |
TKC027225
|
Q96RI1 |
Bile acid receptor |
None |
5900 |
nM |
IC50 |
TKC035272
|
Q96RI1 |
Bile acid receptor |
None |
22387 |
nM |
Potency |
TKC045729
|
Q96RI1 |
Bile acid receptor |
None |
>100000 |
nM |
IC50 |
TKC045739
|
Q96RI1 |
Bile acid receptor |
None |
60400 |
nM |
IC50 |
TKC045844
|
Q96RI1 |
Bile acid receptor |
None |
24800 |
nM |
IC50 |
TKC045846
|
Q96RI1 |
Bile acid receptor |
None |
81100 |
nM |
IC50 |
TKC046058
|
Q96RI1 |
Bile acid receptor |
None |
31600 |
nM |
IC50 |
TKC046480
|
Q96RI1 |
Bile acid receptor |
None |
24000 |
nM |
EC50 |
TKC048922
|
Q96RI1 |
Bile acid receptor |
None |
8800 |
nM |
EC50 |
TKC048923
|
Q96RI1 |
Bile acid receptor |
None |
3570 |
nM |
EC50 |
TKC048938
|
Q96RI1 |
Bile acid receptor |
None |
15100 |
nM |
EC50 |
TKC048939
|
Q96RI1 |
Bile acid receptor |
None |
25290 |
nM |
EC50 |
TKC048940
|
Q96RI1 |
Bile acid receptor |
None |
4740 |
nM |
EC50 |
TKC048951
|
Q96RI1 |
Bile acid receptor |
None |
3260 |
nM |
EC50 |
TKC050873
|
Q96RI1 |
Bile acid receptor |
None |
3030 |
nM |
EC50 |
TKC050874
|
Q96RI1 |
Bile acid receptor |
None |
140 |
nM |
EC50 |
TKC050875
|
Q96RI1 |
Bile acid receptor |
None |
2400 |
nM |
EC50 |
TKC052230
|
Q96RI1 |
Bile acid receptor |
None |
13300 |
nM |
EC50 |
TKC052231
|
Q96RI1 |
Bile acid receptor |
None |
5660 |
nM |
EC50 |
TKC052444
|
Q96RI1 |
Bile acid receptor |
None |
10400 |
nM |
EC50 |
TKC053303
|
Q96RI1 |
Bile acid receptor |
None |
40740 |
nM |
EC50 |
TKC054499
|
Q96RI1 |
Bile acid receptor |
None |
20240 |
nM |
EC50 |
TKC055291
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC055602
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC056482
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC061474
|
Q96RI1 |
Bile acid receptor |
None |
4 |
nM |
Potency |
TKC062736
|
Q96RI1 |
Bile acid receptor |
None |
5640 |
nM |
EC50 |
TKC063162
|
Q96RI1 |
Bile acid receptor |
None |
29680 |
nM |
EC50 |
TKC063163
|
Q96RI1 |
Bile acid receptor |
None |
10160 |
nM |
EC50 |
TKC063164
|
Q96RI1 |
Bile acid receptor |
None |
15310 |
nM |
EC50 |
TKC063165
|
Q96RI1 |
Bile acid receptor |
None |
64890 |
nM |
EC50 |
TKC063168
|
Q96RI1 |
Bile acid receptor |
None |
940 |
nM |
EC50 |
TKC063169
|
Q96RI1 |
Bile acid receptor |
None |
8900 |
nM |
EC50 |
TKC064374
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC064856
|
Q96RI1 |
Bile acid receptor |
None |
6000 |
nM |
EC50 |
TKC064857
|
Q96RI1 |
Bile acid receptor |
None |
12140 |
nM |
EC50 |
TKC064858
|
Q96RI1 |
Bile acid receptor |
None |
15470 |
nM |
EC50 |
TKC064860
|
Q96RI1 |
Bile acid receptor |
None |
24090 |
nM |
EC50 |
TKC066169
|
Q96RI1 |
Bile acid receptor |
None |
35481 |
nM |
Potency |
TKC074296
|
Q96RI1 |
Bile acid receptor |
None |
20150 |
nM |
EC50 |
TKC074867
|
Q96RI1 |
Bile acid receptor |
None |
1 |
nM |
Potency |
TKC075769
|
Q96RI1 |
Bile acid receptor |
None |
18 |
nM |
Potency |
TKC077533
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077595
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077599
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077601
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077608
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077609
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077612
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077626
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC077689
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082589
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082597
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082600
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082608
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082609
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082639
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082652
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082703
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082710
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082711
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC082712
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC086929
|
Q96RI1 |
Bile acid receptor |
None |
2 |
nM |
Potency |
TKC087988
|
Q96RI1 |
Bile acid receptor |
None |
7080 |
nM |
Potency |
TKC087991
|
Q96RI1 |
Bile acid receptor |
None |
70795 |
nM |
Potency |
TKC092297
|
Q96RI1 |
Bile acid receptor |
None |
39811 |
nM |
Potency |
TKC092348
|
Q96RI1 |
Bile acid receptor |
None |
25119 |
nM |
Potency |
TKC093375
|
Q96RI1 |
Bile acid receptor |
None |
9000 |
nM |
IC50 |
TKC096012
|
Q96RI1 |
Bile acid receptor |
None |
17783 |
nM |
Potency |
TKC100644
|
Q96RI1 |
Bile acid receptor |
None |
39811 |
nM |
Potency |
TKC102407
|
Q96RI1 |
Bile acid receptor |
None |
22387 |
nM |
Potency |
TKC103074
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC104925
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC105149
|
Q96RI1 |
Bile acid receptor |
None |
1 |
% |
Activity |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
3400 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
13000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
27000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8300 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
>01000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
>10000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
>10000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
>10000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
18000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
18000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
18000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
13000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
21000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
10000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8660 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
9000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8660 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8660 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
3500 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
11700 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8660 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
13000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
6310 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
13000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
27000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
13000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
15000 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
8660 |
nM |
EC50 |
TKC106240
|
Q96RI1 |
Bile acid receptor |
None |
>10000 |
nM |
EC50 |
TKC106250
|
Q96RI1 |
Bile acid receptor |
None |
50000 |
nM |
EC50 |
TKC107086
|
Q96RI1 |
Bile acid receptor |
None |
28184 |
nM |
Potency |
TKC107735
|
Q96RI1 |
Bile acid receptor |
None |
15849 |
nM |
Potency |
TKC108191
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC108536
|
Q96RI1 |
Bile acid receptor |
None |
4 |
nM |
Potency |
TKC109619
|
Q96RI1 |
Bile acid receptor |
None |
50000 |
nM |
EC50 |
TKC109622
|
Q96RI1 |
Bile acid receptor |
None |
2 |
% |
Activity |
TKC111390
|
Q96RI1 |
Bile acid receptor |
None |
80 |
% |
Inhibition |
TKC112787
|
Q96RI1 |
Bile acid receptor |
None |
5 |
% |
Activity |
TKC113499
|
Q96RI1 |
Bile acid receptor |
None |
30 |
% |
Activity |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
12000 |
nM |
EC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
100000 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
10000 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
12000 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
89360 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
4100 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
41000 |
nM |
IC50 |
TKC114511
|
Q96RI1 |
Bile acid receptor |
None |
44000 |
nM |
IC50 |
TKC115268
|
Q96RI1 |
Bile acid receptor |
None |
44668 |
nM |
Potency |
TKC117705
|
Q96RI1 |
Bile acid receptor |
None |
>9 |
% |
Efficacy |
TKC117716
|
Q96RI1 |
Bile acid receptor |
None |
33180 |
nM |
EC50 |
TKC117717
|
Q96RI1 |
Bile acid receptor |
None |
10230 |
nM |
EC50 |
TKC123088
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC131507
|
Q96RI1 |
Bile acid receptor |
None |
2500 |
nM |
IC50 |
TKC134780
|
Q96RI1 |
Bile acid receptor |
None |
35481 |
nM |
Potency |
TKC137135
|
Q96RI1 |
Bile acid receptor |
None |
2400 |
nM |
IC50 |
TKC137137
|
Q96RI1 |
Bile acid receptor |
None |
75000 |
nM |
IC50 |
TKC137142
|
Q96RI1 |
Bile acid receptor |
None |
24000 |
nM |
IC50 |
TKC137199
|
Q96RI1 |
Bile acid receptor |
None |
64500 |
nM |
IC50 |
TKC137200
|
Q96RI1 |
Bile acid receptor |
None |
25300 |
nM |
IC50 |
TKC141147
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC141164
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC141622
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC144889
|
Q96RI1 |
Bile acid receptor |
None |
189050 |
nM |
EC50 |
TKC145498
|
Q96RI1 |
Bile acid receptor |
None |
3360 |
nM |
EC50 |
TKC145848
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC145932
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC147336
|
Q96RI1 |
Bile acid receptor |
None |
34190 |
nM |
EC50 |
TKC150706
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC151412
|
Q96RI1 |
Bile acid receptor |
None |
110 |
nM |
EC50 |
TKC151556
|
Q96RI1 |
Bile acid receptor |
None |
2100 |
nM |
EC50 |
TKC152742
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC152765
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC152829
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC166596
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC167188
|
Q96RI1 |
Bile acid receptor |
None |
8100 |
nM |
IC50 |
TKC170602
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC170603
|
Q96RI1 |
Bile acid receptor |
None |
0 |
nM |
EC50 |
TKC203882
|
Q96RI1 |
Bile acid receptor |
None |
7320 |
nM |
EC50 |
TKC206249
|
Q96RI1 |
Bile acid receptor |
None |
12430 |
nM |
EC50 |
TKC206344
|
Q96RI1 |
Bile acid receptor |
None |
90 |
nM |
EC50 |
TKC206652
|
Q96RI1 |
Bile acid receptor |
None |
447 |
nM |
Potency |
TKC206670
|
Q96RI1 |
Bile acid receptor |
None |
3000 |
nM |
EC50 |
TKC206671
|
Q96RI1 |
Bile acid receptor |
None |
3000 |
nM |
EC50 |
TKC206672
|
Q96RI1 |
Bile acid receptor |
None |
45000 |
nM |
EC50 |
TKC206688
|
Q96RI1 |
Bile acid receptor |
None |
28184 |
nM |
Potency |
TKC206759
|
Q96RI1 |
Bile acid receptor |
None |
22387 |
nM |
Potency |
TKC206760
|
Q96RI1 |
Bile acid receptor |
None |
100000 |
nM |
EC50 |
TKC206760
|
Q96RI1 |
Bile acid receptor |
None |
18 |
nM |
IC50 |
TKC206760
|
Q96RI1 |
Bile acid receptor |
None |
20000 |
nM |
EC50 |
TKC206760
|
Q96RI1 |
Bile acid receptor |
None |
6700 |
nM |
EC50 |
TKC206812
|
Q96RI1 |
Bile acid receptor |
None |
130 |
nM |
EC50 |
TKC206812
|
Q96RI1 |
Bile acid receptor |
None |
5000 |
nM |
Ki |
TKC206816
|
Q96RI1 |
Bile acid receptor |
None |
12589 |
nM |
Potency |
TKC206884
|
Q96RI1 |
Bile acid receptor |
None |
25119 |
nM |
Potency |
TKC206884
|
Q96RI1 |
Bile acid receptor |
None |
2 |
% |
Efficacy |
TKC206884
|
Q96RI1 |
Bile acid receptor |
None |
>100000 |
nM |
EC50 |
TKC206884
|
Q96RI1 |
Bile acid receptor |
None |
>100000 |
nM |
EC50 |
TKC206885
|
Q96RI1 |
Bile acid receptor |
None |
100000 |
nM |
EC50 |
TKC206927
|
Q96RI1 |
Bile acid receptor |
None |
520 |
nM |
EC50 |