Basic Information

Terpenoid ID TKC112788
Cell line 0
Protein target 6
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112788 O15439 ATP-binding cassette sub-family C member 4 ABCC4 10000 nM IC50
TKC112788 P46720 Solute carrier organic anion transporter family member 1A1 Slco1a1 6000 nM Km
TKC112788 Q9UNQ0 Broad substrate specificity ATP-binding cassette transporter ABCG2 ABCG2 30 % Activity
TKC112788 O70127 Bile salt export pump Abcb11 1200 nM IC50
TKC112788 Q63120 ATP-binding cassette sub-family C member 2 Abcc2 1500 nM Km
TKC112788 O35913 Solute carrier organic anion transporter family member 1A4 Slco1a4 14600 nM Km
TKC112788 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 47800 nM EC50
TKC112788 P33527 Multidrug resistance-associated protein 1 ABCC1 11 % Activity
TKC112788 Q96QA9 ABC-type glutathione-S-conjugate transporter MRP3 8 % Activity
TKC112788 O88563 ATP-binding cassette sub-family C member 3 Abcc3 12 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q9UNQ0 ABCG2_HUMAN Irritable bowel syndrome [ICD-11: DD91]
Q9UNQ0 ABCG2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P33527 MRP1_HUMAN Gout [ICD-11: FA25]