Basic Information

Terpenoid ID TKC206765
Cell line 0
Protein target 13
DiseaseNCIT 0
ORDO 0
ICD 18

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206765 MCF7 5.0 nM EC50 C4194
TKC206765 HepG2 28184.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206765 P04062 Lysosomal acid glucosylceramidase GBA1 4467 nM Potency
TKC206765 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 5805 nM Potency
TKC206765 P43220 Glucagon-like peptide 1 receptor GLP1R 15849 nM Potency
TKC206765 O75164 Lysine-specific demethylase 4A KDM4A 89125 nM Potency
TKC206765 Q9UNA4 DNA polymerase iota POLI 89125 nM Potency
TKC206765 O75496 Geminin GMNN 29093 nM Potency
TKC206765 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 7080 nM Potency
TKC206765 P39748 Flap endonuclease 1 FEN1 112202 nM Potency
TKC206765 Q92731 Estrogen receptor beta ESR2 18000000 M-1 Ka
TKC206765 P02545 Prelamin-A/C LMNA 25119 nM Potency
TKC206765 P0DTE4 UDP-glucuronosyltransferase 2A1 UGT2A1 105 pm/min/mg Activity
TKC206765 P22309 UDP-glucuronosyltransferase 1A1 UGT1A1 0 pm/min/mg Activity
TKC206765 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 32 pm/min/mg Activity
TKC206765 P54855 UDP-glucuronosyltransferase 2B15 UGT2B15 2 pm/min/mg Activity
TKC206765 Q9HAW9 UDP-glucuronosyltransferase 1A8 UGT1A8 33 pm/min/mg Activity
TKC206765 P16662 UDP-glucuronosyltransferase 2B7 UGT2B7 5 total picomoles Activity
TKC206765 P04278 Sex hormone-binding globulin SHBG 1 nM Kd
TKC206765 P08185 Corticosteroid-binding globulin SERPINA6 10000 nM Ki
TKC206765 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 HSD17B7 5 % Inhibition
TKC206765 O09028 Gamma-aminobutyric acid receptor subunit pi Gabrp 1867 nM IC50
TKC206765 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 7010 nM EC50
TKC206765 P06133 UDP-glucuronosyltransferase 2B4 UGT2B4 12 total picomoles Activity
TKC206765 O75795 UDP-glucuronosyltransferase 2B17 UGT2B17 0 pm/min/mg Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q92731 ESR2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q92731 ESR2_HUMAN Cushing syndrome [ICD-11: 5A70]
Q92731 ESR2_HUMAN Menopausal disorder [ICD-11: GA30]
Q92731 ESR2_HUMAN Vasomotor/allergic rhinitis [ICD-11: CA08]
Q92731 ESR2_HUMAN Hepatitis virus infection [ICD-11: 1E50-1E51]
Q92731 ESR2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q92731 ESR2_HUMAN Prostate cancer [ICD-11: 2C82]
Q92731 ESR2_HUMAN Alzheimer disease [ICD-11: 8A20]
Q92731 ESR2_HUMAN Indeterminate colitis [ICD-11: DD72]
Q92731 ESR2_HUMAN Prostate hyperplasia [ICD-11: GA90]
Q92731 ESR2_HUMAN Sepsis [ICD-11: 1G40-1G41]
Q92731 ESR2_HUMAN Irregularities [ICD-11: N.A.]
Q92731 ESR2_HUMAN Trematode disease [ICD-11: 1F8Y]
Q92731 ESR2_HUMAN Low bone mass disorder [ICD-11: FB83]
Q92731 ESR2_HUMAN Thrombocytopenia [ICD-11: 3B64]
Q92731 ESR2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q92731 ESR2_HUMAN Herpes simplex infection [ICD-11: 1F00]
Q92731 ESR2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P22309 UD11_HUMAN Inborn porphyrin/heme metabolism error [ICD-11: 5C58]
P08185 CBG_HUMAN Asthma [ICD-11: CA23]
P08185 CBG_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P08185 CBG_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P08185 CBG_HUMAN Retinopathy [ICD-11: 9B71]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]