Basic Information

Terpenoid ID TKC046058
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC046058 HT-29 HT 29; HT29 910.0 nM IC50 C4349
TKC046058 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 5900.0 nM IC50 C5214
TKC046058 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 2.0 ug.mL-1 IC50 C21604
TKC046058 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 17.0 ug.mL-1 IC50 C27677
TKC046058 A549 17.0 ug.mL-1 IC50 C3512
TKC046058 KB KB (HeLa derivative); HeLa-KB; Strain KB 17.0 ug.mL-1 IC50 C27677
TKC046058 CCRF S-180 CCRF S 180 II; S-180 II; CCRF S-180; S-180; S180; Sarcoma-180; Sarcoma 180; CCRF-180II 50.0 % Activity C24017
TKC046058 MCF7 320.0 nM IC50 C4194
TKC046058 T47D 5200.0 nM IC50 C4194
TKC046058 NCI-H69 NCI-H-69; NCI H69; H69; H-69; NCIH69; NCI-HUT-69; H69/P; NCI-H69C; H69C; H69c 57000.0 nM IC50 C4917 Orphanet_70573

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC046058 Q96RI1 Bile acid receptor NR1H4 31600 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]