Basic Information

Terpenoid ID TKC118553
Chirality TKC206906
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC118553 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 2818 nM Potency
TKC118553 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 103 % Inhibition
TKC118553 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 98 % Inhibition
TKC118553 O00255 Menin MEN1 39811 nM Potency
TKC118553 Q92830 Histone acetyltransferase KAT2A KAT2A 3162 nM Potency
TKC118553 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 10000 nM Potency
TKC118553 P02545 Prelamin-A/C LMNA 19953 nM Potency
TKC118553 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 6080 nM EC50
TKC118553 Q96BI3 Gamma-secretase subunit APH-1A APH1A 5680 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]