Basic Information

Terpenoid ID TKC046480
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 19

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC046480 K562 K562; K.562; K 562; KO; GM05372; GM05372E 16000.0 nM LC50 C9110 Orphanet_521
TKC046480 K562 K562; K.562; K 562; KO; GM05372; GM05372E 16000.0 nM LC50 C9110 Orphanet_521

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC046480 Q9P8Q7 Isocitrate lyase ICL1 5000 nM IC50
TKC046480 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 9000 nM IC50
TKC046480 Q96RI1 Bile acid receptor NR1H4 24000 nM EC50
TKC046480 Q9S446 Class A sortase SrtA srtA >200000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P05023 AT1A1_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
P05023 AT1A1_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P05023 AT1A1_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P05023 AT1A1_HUMAN Heart failure [ICD-11: BD10-BD1Z]
P05023 AT1A1_HUMAN Hyperhidrosis [ICD-11: EE00]
P05023 AT1A1_HUMAN Malaria [ICD-11: 1F40-1F45]
P05023 AT1A1_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P05023 AT1A1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]