Basic Information

Terpenoid ID TKC170603
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC170603 A2780 A-2780; 2780; A2780S; A2780par 15700.0 nM EC50 C7979 Orphanet_454723
TKC170603 A549 8200.0 nM EC50 C3512
TKC170603 MCF7 10700.0 nM EC50 C4194
TKC170603 HT-29 HT 29; HT29 10200.0 nM EC50 C4349
TKC170603 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 11200.0 nM EC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC170603 Q96RI1 Bile acid receptor NR1H4 0 nM EC50
TKC170603 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 >0 % Efficacy

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]