Basic Information

Terpenoid ID TKC206814
Chirality TKC114568
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206814 HEp-2 Hep-2; HEP-2; Hep2 (HeLa derivative); HEp-2/HeLa; Hep 2; Hep2; HEp2; HEP2; H.Ep.-2; H.Ep. #2; H.Ep. No. 2; Hep II; Human Epidermoid carcinoma #2; Human Epithelioma-2 1.0 ug ml-1 LD50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206814 P0DTD1 Replicase polyprotein 1ab rep 12 % Inhibition
TKC206814 O35627 Nuclear receptor subfamily 1 group I member 3 Nr1i3 73 % Remaining activity
TKC206814 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 290 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]