Basic Information

Terpenoid ID TKC019374
Chirality TKC074866
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC019374 PC-3 PC3; PC.3 10.0 % Activity C4863

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC019374 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 82 % Inhibition
TKC019374 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 58 % Inhibition
TKC019374 Q96RI1 Bile acid receptor NR1H4 4 nM Potency
TKC019374 Q6RI86 Transient receptor potential cation channel subfamily A member 1 Trpa1 11700 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]