Basic Information

Terpenoid ID TKC137137
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC137137 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 2.0 ug.mL-1 IC50 C21604
TKC137137 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 15.0 ug.mL-1 IC50 C27677
TKC137137 A549 15.0 ug.mL-1 IC50 C3512
TKC137137 KB KB (HeLa derivative); HeLa-KB; Strain KB 14.0 ug.mL-1 IC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC137137 Q96RI1 Bile acid receptor NR1H4 75000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]