Basic Information

Name [ICD-11: 2A83]
Protein Number 28
Molecule Number 265

Active subnetwork

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC005454 O14746 Telomerase reverse transcriptase None 75 % Inhibition
TKC014568 O14746 Telomerase reverse transcriptase None 65 % Inhibition
TKC035208 O14746 Telomerase reverse transcriptase None 65000 nM IC50
TKC066096 O14746 Telomerase reverse transcriptase None 780 nM IC50
TKC134702 O14746 Telomerase reverse transcriptase None 4000 nM IC50
TKC051021 P01375 Tumor necrosis factor None 9 nM Kd
TKC051029 P01375 Tumor necrosis factor None 9 nM Kd
TKC055869 P01375 Tumor necrosis factor None 10880 nM IC50
TKC063751 P01375 Tumor necrosis factor None 19 nM Kd
TKC064986 P01375 Tumor necrosis factor None 3 nM Kd
TKC075769 P01375 Tumor necrosis factor None 376 nM Potency
TKC101833 P01375 Tumor necrosis factor None 8 nM Kd
TKC145547 P01375 Tumor necrosis factor None 2 nM Kd
TKC148618 P01375 Tumor necrosis factor None 17 nM Kd
TKC151763 P01375 Tumor necrosis factor None 8 nM Kd
TKC151876 P01375 Tumor necrosis factor None 6 % Inhibition
TKC008187 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30200 nM IC50
TKC023515 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 53 % Inhibition
TKC025574 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 52 % Inhibition
TKC026893 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21 % Inhibition
TKC026895 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 61 % Inhibition
TKC057019 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 22300 nM IC50
TKC100777 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30 % Inhibition
TKC101031 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1500 nM IC50
TKC101538 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 39 % Inhibition
TKC101847 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1000 nM IC50
TKC103703 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 40 % Inhibition
TKC137314 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 8400 nM IC50
TKC138471 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21700 nM IC50
TKC026717 P06239 Tyrosine-protein kinase Lck None 80 ug.mL-1 IC50
TKC046110 P06239 Tyrosine-protein kinase Lck None 45 % Activity
TKC105249 P06239 Tyrosine-protein kinase Lck None 92 ug.mL-1 IC50
TKC111609 P06239 Tyrosine-protein kinase Lck None 47 % Activity
TKC111658 P06239 Tyrosine-protein kinase Lck None 42 % Activity
TKC118419 P06239 Tyrosine-protein kinase Lck None 95 % Inhibition
TKC021518 P07477 Trypsin-1 None >200000 nM IC50
TKC021519 P07477 Trypsin-1 None >200000 nM IC50
TKC055903 P07477 Trypsin-1 None 70 nM IC50
TKC105803 P07477 Trypsin-1 None >200000 nM IC50
TKC130567 P07477 Trypsin-1 None >200000 nM IC50
TKC006863 P07900 Heat shock protein HSP 90-alpha None 1000 nM Kd
TKC006886 P07900 Heat shock protein HSP 90-alpha None 28 nM Kd
TKC006887 P07900 Heat shock protein HSP 90-alpha None 1739 nM Kd
TKC022121 P07900 Heat shock protein HSP 90-alpha None 2388 nM Kd
TKC022128 P07900 Heat shock protein HSP 90-alpha None 5925 nM Kd
TKC023022 P07900 Heat shock protein HSP 90-alpha None 12 nM Kd
TKC023024 P07900 Heat shock protein HSP 90-alpha None 26 nM Kd
TKC044085 P07900 Heat shock protein HSP 90-alpha None <195 nM AC50
TKC052570 P07900 Heat shock protein HSP 90-alpha None 49 nM Kd
TKC061684 P07900 Heat shock protein HSP 90-alpha None 33 nM Kd
TKC066096 P07900 Heat shock protein HSP 90-alpha None 1408 nM AC50
TKC066096 P07900 Heat shock protein HSP 90-alpha None 12 % Inhibition
TKC096901 P07900 Heat shock protein HSP 90-alpha None 2295 nM AC50
TKC104518 P07900 Heat shock protein HSP 90-alpha None 348 nM Kd
TKC118419 P07900 Heat shock protein HSP 90-alpha None 363 nM AC50
TKC129193 P07900 Heat shock protein HSP 90-alpha None 3791 nM AC50
TKC143885 P07900 Heat shock protein HSP 90-alpha None 649 nM AC50
TKC161438 P07900 Heat shock protein HSP 90-alpha None 73 nM Kd
TKC024886 P08069 Insulin-like growth factor 1 receptor None 11800 nM IC50
TKC025690 P08069 Insulin-like growth factor 1 receptor None 3310 nM IC50
TKC115259 P08069 Insulin-like growth factor 1 receptor None 3160 nM IC50
TKC115261 P08069 Insulin-like growth factor 1 receptor None 2420 nM IC50
TKC115272 P08069 Insulin-like growth factor 1 receptor None >100000 nM IC50
TKC115273 P08069 Insulin-like growth factor 1 receptor None 2300 nM IC50
TKC152148 P08069 Insulin-like growth factor 1 receptor None 2770 nM IC50
TKC152157 P08069 Insulin-like growth factor 1 receptor None 2460 nM IC50
TKC174547 P08069 Insulin-like growth factor 1 receptor None >100000 nM IC50
TKC035272 P10415 Apoptosis regulator Bcl-2 None 170 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 260 nM IC50
TKC035272 P10415 Apoptosis regulator Bcl-2 None 320 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 440 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 440 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 1191 nM IC50
TKC035272 P10415 Apoptosis regulator Bcl-2 None 450 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 320 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 600 nM IC50
TKC035272 P10415 Apoptosis regulator Bcl-2 None 420 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 10100 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 4800 nM Kd
TKC035272 P10415 Apoptosis regulator Bcl-2 None 2110 nM IC50
TKC035272 P10415 Apoptosis regulator Bcl-2 None 558 nM Ki
TKC035272 P10415 Apoptosis regulator Bcl-2 None 320 nM Ki
TKC134945 P10415 Apoptosis regulator Bcl-2 None 1460 nM Ki
TKC151761 P10415 Apoptosis regulator Bcl-2 None >10000 nM GI50
TKC200866 P10415 Apoptosis regulator Bcl-2 None >10000 nM GI50
TKC151761 P11362 Fibroblast growth factor receptor 1 None >10000 nM IC50
TKC200866 P11362 Fibroblast growth factor receptor 1 None >10000 nM IC50
TKC011761 P12931 Proto-oncogene tyrosine-protein kinase Src None 61 % Inhibition
TKC024886 P12931 Proto-oncogene tyrosine-protein kinase Src None 8620 nM IC50
TKC025690 P12931 Proto-oncogene tyrosine-protein kinase Src None 19700 nM IC50
TKC115259 P12931 Proto-oncogene tyrosine-protein kinase Src None 2400 nM IC50
TKC115261 P12931 Proto-oncogene tyrosine-protein kinase Src None 2240 nM IC50
TKC115272 P12931 Proto-oncogene tyrosine-protein kinase Src None >100000 nM IC50
TKC115273 P12931 Proto-oncogene tyrosine-protein kinase Src None 1480 nM IC50
TKC135974 P12931 Proto-oncogene tyrosine-protein kinase Src None 35800 nM IC50
TKC151761 P12931 Proto-oncogene tyrosine-protein kinase Src None >10000 nM IC50
TKC152148 P12931 Proto-oncogene tyrosine-protein kinase Src None 1910 nM IC50
TKC152157 P12931 Proto-oncogene tyrosine-protein kinase Src None 2170 nM IC50
TKC174547 P12931 Proto-oncogene tyrosine-protein kinase Src None >100000 nM IC50
TKC200866 P12931 Proto-oncogene tyrosine-protein kinase Src None >10000 nM IC50
TKC205544 P14416 D(2) dopamine receptor None 687 nM Ki
TKC205544 P14416 D(2) dopamine receptor None 280 nM Ki
TKC205544 P14416 D(2) dopamine receptor None 398.1 nM Ki
TKC206544 P14416 D(2) dopamine receptor None >10000 nM Ki
TKC075756 P17948 Vascular endothelial growth factor receptor 1 None 1001 nM Ki
TKC034640 P21397 Amine oxidase [flavin-containing] A None >1000000 nM Ki
TKC146423 P21397 Amine oxidase [flavin-containing] A None 170000 nM IC50
TKC034640 P27338 Amine oxidase [flavin-containing] B None 800 nM Ki
TKC146423 P27338 Amine oxidase [flavin-containing] B None 128000 nM IC50
TKC024886 P30530 Tyrosine-protein kinase receptor UFO None 13100 nM IC50
TKC025690 P30530 Tyrosine-protein kinase receptor UFO None 14700 nM IC50
TKC115259 P30530 Tyrosine-protein kinase receptor UFO None 21900 nM IC50
TKC115261 P30530 Tyrosine-protein kinase receptor UFO None 14700 nM IC50
TKC115272 P30530 Tyrosine-protein kinase receptor UFO None >100000 nM IC50
TKC115273 P30530 Tyrosine-protein kinase receptor UFO None 20200 nM IC50
TKC152148 P30530 Tyrosine-protein kinase receptor UFO None 16900 nM IC50
TKC152157 P30530 Tyrosine-protein kinase receptor UFO None 32600 nM IC50
TKC174547 P30530 Tyrosine-protein kinase receptor UFO None >100000 nM IC50
TKC011761 P31749 RAC-alpha serine/threonine-protein kinase None 54 % Inhibition
TKC016414 P31749 RAC-alpha serine/threonine-protein kinase None 36 % Activity
TKC024886 P31749 RAC-alpha serine/threonine-protein kinase None 48400 nM IC50
TKC025690 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC044763 P31749 RAC-alpha serine/threonine-protein kinase None 100 % Inhibition
TKC115259 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC115261 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC115272 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC115273 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC118419 P31749 RAC-alpha serine/threonine-protein kinase None 96 % Inhibition
TKC152148 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC152157 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC174547 P31749 RAC-alpha serine/threonine-protein kinase None >100000 nM IC50
TKC206776 P31749 RAC-alpha serine/threonine-protein kinase None 3 uM Activity
TKC205544 P35462 D(3) dopamine receptor None 2489 nM Ki
TKC205544 P35462 D(3) dopamine receptor None 3981.07 nM Ki
TKC206544 P35462 D(3) dopamine receptor None >10000 nM Ki
TKC206549 P35869 Aryl hydrocarbon receptor None 17783 nM Potency
TKC024886 P35968 Vascular endothelial growth factor receptor 2 None 4810 nM IC50
TKC025690 P35968 Vascular endothelial growth factor receptor 2 None 3660 nM IC50
TKC051154 P35968 Vascular endothelial growth factor receptor 2 None 40 % Inhibition
TKC051155 P35968 Vascular endothelial growth factor receptor 2 None 46 % Inhibition
TKC065375 P35968 Vascular endothelial growth factor receptor 2 None 0 % Inhibition
TKC102689 P35968 Vascular endothelial growth factor receptor 2 None 0 % Inhibition
TKC108267 P35968 Vascular endothelial growth factor receptor 2 None 0 % Inhibition
TKC115259 P35968 Vascular endothelial growth factor receptor 2 None 4950 nM IC50
TKC115261 P35968 Vascular endothelial growth factor receptor 2 None 4600 nM IC50
TKC115272 P35968 Vascular endothelial growth factor receptor 2 None >100000 nM IC50
TKC115273 P35968 Vascular endothelial growth factor receptor 2 None 4850 nM IC50
TKC146202 P35968 Vascular endothelial growth factor receptor 2 None 61 % Inhibition
TKC152148 P35968 Vascular endothelial growth factor receptor 2 None 4350 nM IC50
TKC152157 P35968 Vascular endothelial growth factor receptor 2 None 6010 nM IC50
TKC174547 P35968 Vascular endothelial growth factor receptor 2 None >100000 nM IC50
TKC207124 P35968 Vascular endothelial growth factor receptor 2 None 40400 nM IC50
TKC003060 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC005454 P40763 Signal transducer and activator of transcription 3 None 4600 nM IC50
TKC016414 P40763 Signal transducer and activator of transcription 3 None >10000 nM EC50
TKC020636 P40763 Signal transducer and activator of transcription 3 None 6900 nM IC50
TKC020796 P40763 Signal transducer and activator of transcription 3 None 22900 nM IC50
TKC020867 P40763 Signal transducer and activator of transcription 3 None 26 % Inhibition
TKC020868 P40763 Signal transducer and activator of transcription 3 None 31 % Inhibition
TKC020869 P40763 Signal transducer and activator of transcription 3 None 49 % Inhibition
TKC022393 P40763 Signal transducer and activator of transcription 3 None 89500 nM IC50
TKC022771 P40763 Signal transducer and activator of transcription 3 None >100000 nM IC50
TKC028367 P40763 Signal transducer and activator of transcription 3 None 4100 nM IC50
TKC030728 P40763 Signal transducer and activator of transcription 3 None 2 % Inhibition
TKC033506 P40763 Signal transducer and activator of transcription 3 None 2400 nM IC50
TKC033507 P40763 Signal transducer and activator of transcription 3 None 2300 nM IC50
TKC036334 P40763 Signal transducer and activator of transcription 3 None 4 % Inhibition
TKC038766 P40763 Signal transducer and activator of transcription 3 None 1 % Inhibition
TKC039282 P40763 Signal transducer and activator of transcription 3 None 2 % Inhibition
TKC042554 P40763 Signal transducer and activator of transcription 3 None 6300 nM IC50
TKC042556 P40763 Signal transducer and activator of transcription 3 None 110000 nM IC50
TKC044507 P40763 Signal transducer and activator of transcription 3 None 4 % Inhibition
TKC044595 P40763 Signal transducer and activator of transcription 3 None 4 % Inhibition
TKC044621 P40763 Signal transducer and activator of transcription 3 None 3 % Inhibition
TKC044669 P40763 Signal transducer and activator of transcription 3 None 4 % Inhibition
TKC047957 P40763 Signal transducer and activator of transcription 3 None 17100 nM IC50
TKC047959 P40763 Signal transducer and activator of transcription 3 None >30000 nM IC50
TKC047961 P40763 Signal transducer and activator of transcription 3 None >30000 nM IC50
TKC048029 P40763 Signal transducer and activator of transcription 3 None 270 nM IC50
TKC048030 P40763 Signal transducer and activator of transcription 3 None 19200 nM IC50
TKC048031 P40763 Signal transducer and activator of transcription 3 None 590 nM IC50
TKC051029 P40763 Signal transducer and activator of transcription 3 None 60000 nM MIC
TKC060882 P40763 Signal transducer and activator of transcription 3 None >25000 nM IC50
TKC075769 P40763 Signal transducer and activator of transcription 3 None 1862 nM IC50
TKC077689 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC078334 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC087623 P40763 Signal transducer and activator of transcription 3 None >100000 nM IC50
TKC087625 P40763 Signal transducer and activator of transcription 3 None 7000 nM IC50
TKC093311 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC100739 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC101161 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC103159 P40763 Signal transducer and activator of transcription 3 None 3000 nM IC50
TKC103189 P40763 Signal transducer and activator of transcription 3 None 32500 nM IC50
TKC103191 P40763 Signal transducer and activator of transcription 3 None 24800 nM IC50
TKC105152 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC107659 P40763 Signal transducer and activator of transcription 3 None 4 % Inhibition
TKC108773 P40763 Signal transducer and activator of transcription 3 None >50000 nM IC50
TKC112576 P40763 Signal transducer and activator of transcription 3 None 1154 nM IC50
TKC134761 P40763 Signal transducer and activator of transcription 3 None 48 % Inhibition
TKC135961 P40763 Signal transducer and activator of transcription 3 None 73000 nM IC50
TKC135978 P40763 Signal transducer and activator of transcription 3 None 14210 nM IC50
TKC136653 P40763 Signal transducer and activator of transcription 3 None 2 % Inhibition
TKC148207 P40763 Signal transducer and activator of transcription 3 None 15840 nM IC50
TKC149924 P40763 Signal transducer and activator of transcription 3 None 74 % Inhibition
TKC151284 P40763 Signal transducer and activator of transcription 3 None 14000 nM IC50
TKC156528 P40763 Signal transducer and activator of transcription 3 None >30000 nM IC50
TKC206318 P40763 Signal transducer and activator of transcription 3 None 12200 nM IC50
TKC206468 P40763 Signal transducer and activator of transcription 3 None 46 % Inhibition
TKC206627 P40763 Signal transducer and activator of transcription 3 None >100000 nM IC50
TKC206646 P40763 Signal transducer and activator of transcription 3 None 67000 nM IC50
TKC206652 P40763 Signal transducer and activator of transcription 3 None 700 nM IC50
TKC022945 P42345 Serine/threonine-protein kinase mTOR None 4645 nM Potency
TKC032619 P42345 Serine/threonine-protein kinase mTOR None 2931 nM Potency
TKC035272 P42345 Serine/threonine-protein kinase mTOR None 2612 nM Potency
TKC035984 P42345 Serine/threonine-protein kinase mTOR None 4 nM Potency
TKC084630 P42345 Serine/threonine-protein kinase mTOR None 3690 nM Potency
TKC087988 P42345 Serine/threonine-protein kinase mTOR None 4645 nM Potency
TKC092297 P42345 Serine/threonine-protein kinase mTOR None 13092 nM Potency
TKC118419 P42345 Serine/threonine-protein kinase mTOR None 40 nM IC50
TKC118419 P42345 Serine/threonine-protein kinase mTOR None 9200 nM Kd
TKC205544 P42345 Serine/threonine-protein kinase mTOR None 14689 nM Potency
TKC206622 P42345 Serine/threonine-protein kinase mTOR None 23281 nM Potency
TKC206688 P42345 Serine/threonine-protein kinase mTOR None 16482 nM Potency
TKC009486 P52333 Tyrosine-protein kinase JAK3 None >100 nM IC50
TKC009499 P52333 Tyrosine-protein kinase JAK3 None >100 nM IC50
TKC011761 P52333 Tyrosine-protein kinase JAK3 None 100 nM IC50
TKC031094 P52333 Tyrosine-protein kinase JAK3 None >25 % Inhibition
TKC107626 P52333 Tyrosine-protein kinase JAK3 None 25 % Inhibition
TKC120591 P52333 Tyrosine-protein kinase JAK3 None >100 nM IC50
TKC120592 P52333 Tyrosine-protein kinase JAK3 None >100 nM IC50
TKC120593 P52333 Tyrosine-protein kinase JAK3 None >100 nM IC50
TKC134702 P52333 Tyrosine-protein kinase JAK3 None 25 % Inhibition
TKC151713 P52333 Tyrosine-protein kinase JAK3 None 25 % Inhibition
TKC027726 P52732 Kinesin-like protein KIF11 None 3500 nM IC50
TKC035272 P52732 Kinesin-like protein KIF11 None 10800 nM IC50
TKC035272 P52732 Kinesin-like protein KIF11 None 25000 nM IC50
TKC108557 P52732 Kinesin-like protein KIF11 None 0.3 nM IC50
TKC007963 P55072 Transitional endoplasmic reticulum ATPase None >100000 nM IC50
TKC035272 P55072 Transitional endoplasmic reticulum ATPase None 5386 nM IC50
TKC038988 P55072 Transitional endoplasmic reticulum ATPase None >100000 nM IC50
TKC113058 P55072 Transitional endoplasmic reticulum ATPase None 22000 nM IC50
TKC205544 P61073 C-X-C chemokine receptor type 4 None 21 % Inhibition
TKC028446 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 11400 nM IC50
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 1356 nM IC50
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 162 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 180 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 280 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 310 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 640 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 180 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 180 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 200 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 6543 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 2324 nM Kd
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 190 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 2650 nM Kd
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 190 nM Ki
TKC035272 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 180 nM Ki
TKC039229 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 12900 nM Ki
TKC105178 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 14400 nM Ki
TKC105179 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 4200 nM Ki
TKC134945 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 None 8600 nM Ki
TKC118419 Q9P1W9 Serine/threonine-protein kinase pim-2 None 83 % Activity
TKC014593 Q9UBN7 Histone deacetylase 6 None 80000 nM IC50
TKC020117 Q9UBN7 Histone deacetylase 6 None >2500 nM Ki