Basic Information

Name [ICD-11: 1E50-1E51]
Protein Number 14
Molecule Number 107

Active subnetwork

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC007127 P00533 Epidermal growth factor receptor None 19 % Inhibition
TKC025462 P00533 Epidermal growth factor receptor None >200 ug.mL-1 IC50
TKC025466 P00533 Epidermal growth factor receptor None >200 ug.mL-1 IC50
TKC025475 P00533 Epidermal growth factor receptor None 197 ug.mL-1 IC50
TKC071640 P00533 Epidermal growth factor receptor None >20000 nM IC50
TKC076041 P00533 Epidermal growth factor receptor None 75 % Inhibition
TKC077689 P00533 Epidermal growth factor receptor None >20000 nM IC50
TKC106319 P00533 Epidermal growth factor receptor None 56 nM IC50
TKC108557 P00533 Epidermal growth factor receptor None 0.82 nM Kd
TKC151761 P00533 Epidermal growth factor receptor None >10000 nM IC50
TKC200866 P00533 Epidermal growth factor receptor None >10000 nM IC50
TKC020117 P03956 Interstitial collagenase None 95 % Inhibition
TKC008187 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30200 nM IC50
TKC023515 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 53 % Inhibition
TKC025574 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 52 % Inhibition
TKC026893 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21 % Inhibition
TKC026895 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 61 % Inhibition
TKC057019 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 22300 nM IC50
TKC100777 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 30 % Inhibition
TKC101031 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1500 nM IC50
TKC101538 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 39 % Inhibition
TKC101847 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 1000 nM IC50
TKC103703 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 40 % Inhibition
TKC137314 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 8400 nM IC50
TKC138471 P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase None 21700 nM IC50
TKC025462 P04626 Receptor tyrosine-protein kinase erbB-2 None >200 ug.mL-1 IC50
TKC025466 P04626 Receptor tyrosine-protein kinase erbB-2 None >200 ug.mL-1 IC50
TKC025475 P04626 Receptor tyrosine-protein kinase erbB-2 None 125 ug.mL-1 IC50
TKC026211 P04626 Receptor tyrosine-protein kinase erbB-2 None 6 ug.mL-1 IC50
TKC026214 P04626 Receptor tyrosine-protein kinase erbB-2 None 8 ug.mL-1 IC50
TKC026217 P04626 Receptor tyrosine-protein kinase erbB-2 None 4 ug.mL-1 IC50
TKC026229 P04626 Receptor tyrosine-protein kinase erbB-2 None 8 ug.mL-1 IC50
TKC009193 P08253 72 kDa type IV collagenase None 33260 nM IC50
TKC020117 P08253 72 kDa type IV collagenase None 90 % Inhibition
TKC023429 P08253 72 kDa type IV collagenase None 0 ug.mL-1 IC50
TKC020117 P08254 Stromelysin-1 None 98 % Inhibition
TKC042585 P08254 Stromelysin-1 None 300 nM MIC50
TKC042586 P08254 Stromelysin-1 None 300 nM MIC50
TKC042587 P08254 Stromelysin-1 None 300 nM MIC50
TKC087988 P0DMS8 Adenosine receptor A3 None 2357 nM Ki
TKC096012 P0DMS8 Adenosine receptor A3 None 2982 nM Ki
TKC205544 P0DMS8 Adenosine receptor A3 None 95 nM IC50
TKC206779 P0DMS8 Adenosine receptor A3 None 2674 nM Ki
TKC020117 P14780 Matrix metalloproteinase-9 None 99 % Inhibition
TKC023429 P14780 Matrix metalloproteinase-9 None 1 ug.mL-1 IC50
TKC037777 P14780 Matrix metalloproteinase-9 None 6 ug.mL-1 IC50
TKC039471 P14780 Matrix metalloproteinase-9 None 6 ug.mL-1 IC50
TKC007073 P25105 Platelet-activating factor receptor None 5 uM Binding affinity
TKC105026 P25105 Platelet-activating factor receptor None 575 nM IC50
TKC105028 P25105 Platelet-activating factor receptor None 575 nM IC50
TKC106540 P25105 Platelet-activating factor receptor None 964 nM Ki
TKC147486 P25105 Platelet-activating factor receptor None 4 uM Binding affinity
TKC147612 P25105 Platelet-activating factor receptor None 5 uM Binding affinity
TKC151784 P25105 Platelet-activating factor receptor None 128 nM IC50
TKC205457 P25105 Platelet-activating factor receptor None 1259 nM IC50
TKC038192 Q02127 Dihydroorotate dehydrogenase None 3 % Inhibition
TKC039868 Q02127 Dihydroorotate dehydrogenase None 0 % Inhibition
TKC043742 Q02127 Dihydroorotate dehydrogenase None 0 % Inhibition
TKC079733 Q02127 Dihydroorotate dehydrogenase None 28 % Inhibition
TKC136181 Q02127 Dihydroorotate dehydrogenase None 12 % Inhibition
TKC106240 Q14973 Sodium/bile acid cotransporter None 13 % Activity
TKC106250 Q14973 Sodium/bile acid cotransporter None 3600 nM IC50
TKC109619 Q14973 Sodium/bile acid cotransporter None 3600 nM IC50
TKC109622 Q14973 Sodium/bile acid cotransporter None 8 % Activity
TKC112785 Q14973 Sodium/bile acid cotransporter None 24 % Activity
TKC112787 Q14973 Sodium/bile acid cotransporter None 33 % Activity
TKC206670 Q14973 Sodium/bile acid cotransporter None 14 % Activity
TKC206671 Q14973 Sodium/bile acid cotransporter None 19 % Activity
TKC206760 Q14973 Sodium/bile acid cotransporter None 63 % Activity
TKC206849 Q14973 Sodium/bile acid cotransporter None 5300 nM IC50
TKC023246 Q92731 Estrogen receptor beta None >10000 nM IC50
TKC028029 Q92731 Estrogen receptor beta None <1 % Activity
TKC028037 Q92731 Estrogen receptor beta None 10 % Activity
TKC035272 Q92731 Estrogen receptor beta None >50000 nM IC50
TKC100932 Q92731 Estrogen receptor beta None 25300 nM EC50
TKC101365 Q92731 Estrogen receptor beta None 17690 nM EC50
TKC102448 Q92731 Estrogen receptor beta None 4680 nM EC50
TKC106878 Q92731 Estrogen receptor beta None >10000 nM IC50
TKC110673 Q92731 Estrogen receptor beta None 2.78E+11 M-1 Ka
TKC111721 Q92731 Estrogen receptor beta None 1520000000 M-1 Ka
TKC111727 Q92731 Estrogen receptor beta None 614000000 M-1 Ka
TKC111727 Q92731 Estrogen receptor beta None 0 nM EC50
TKC111738 Q92731 Estrogen receptor beta None 2 nM EC50
TKC111738 Q92731 Estrogen receptor beta None 4 % RSA
TKC111738 Q92731 Estrogen receptor beta None 26 nM IC50
TKC111738 Q92731 Estrogen receptor beta None 540 nM IC50
TKC111738 Q92731 Estrogen receptor beta None 8 nM EC50
TKC112923 Q92731 Estrogen receptor beta None 6 nM EC50
TKC206608 Q92731 Estrogen receptor beta None 4280 nM EC50
TKC206725 Q92731 Estrogen receptor beta None 24 nM Ki
TKC206726 Q92731 Estrogen receptor beta None 11 nM EC50
TKC206759 Q92731 Estrogen receptor beta None >10000 nM IC50
TKC206759 Q92731 Estrogen receptor beta None >10000 nM IC50
TKC206764 Q92731 Estrogen receptor beta None 1 % RBA
TKC206765 Q92731 Estrogen receptor beta None 18000000 M-1 Ka
TKC206769 Q92731 Estrogen receptor beta None 27000000 M-1 Ka
TKC206812 Q92731 Estrogen receptor beta None >5000 nM IC50
TKC206816 Q92731 Estrogen receptor beta None 1000000 nM IC50
TKC055869 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 None 8077 nM IC50
TKC108557 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 None 5012 nM IC50
TKC151761 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 None 7943 nM IC50
TKC200866 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 None 7943 nM IC50
TKC066096 Q9NR96 Toll-like receptor 9 None 3015 nM IC50
TKC076529 Q9NR96 Toll-like receptor 9 None >49739 nM IC50
TKC076529 Q9NR96 Toll-like receptor 9 None >49739 nM IC50
TKC082378 Q9NR96 Toll-like receptor 9 None 7929 nM IC50
TKC082378 Q9NR96 Toll-like receptor 9 None 7929 nM IC50